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Energy drink consumption linked with serious cardiovascular events

Anna Svatikova, M.D., Ph.D., of the Mayo Clinic, Rochester, Minn., and colleagues randomly assigned 25 healthy volunteers (age 18 years or older) to consume a can (480 mL; 16 fl. oz.) of a commercially available energy drink (Rockstar; Rockstar Inc) and placebo drink within 5 minutes, in random order on 2 separate days, maximum 2 weeks apart.

9 Nov 2015

Novartis’ Cosentyx® show no progression in spinal damage in 80% of ankylosing spondylitis patients

Novartis announced today late-breaking two year results for Cosentyx® (secukinumab) showing up to 80% of patients with ankylosing spondylitis (AS) had no radiographic progression in the spine on x-ray assessment. This is the first time that data on structural spinal progression in AS have been presented for an interleukin-17A (IL-17A) inhibitor.

9 Nov 2015

Major US healthcare database has missing pieces

A major source of American health information data contains a handful of glaring flaws related to health risks, say Johns Hopkins researchers in a study published online Wednesday in the journal PLOS ONE.

9 Nov 2015

St. Michael's Hospital study finds that cholesterol-reducing diet also lowers blood pressure

A diet developed for reducing cholesterol also lowers blood pressure, a St. Michael's Hospital study has found.

9 Nov 2015

NTU Singapore scientists harness dead bacteria to destroy colon tumours cells effectively

Scientists from Nanyang Technological University have successfully used dead bacteria to kill colorectal cancer cells. Harvesting the Clostridium sporogenes bacteria found commonly in soil, the NTU team was able to harness the bacteria in its dead form, and its secretions, to destroy colon tumours cells effectively.

9 Nov 2015

Combatting viral and bacterial lung infections with volatile anesthetics: an interview with Dr Chakravarthy

Inhaled anesthetics are fairly common all over the world for minor and extensive surgical procedures in patients of all age groups. In the olden days when anesthesia was first developed, ether was the first inhaled anesthetic. That has been replaced, with the more recent discoveries of sevoflurane, isoflurane, and desflurane.

9 Nov 2015

$Ixazomib’s phase 3 study in relapsed/refractory multiple myeloma presented$

Ixazomib’s phase 3 study in relapsed/refractory multiple myeloma presented

Takeda Pharmaceutical Company Limited today announced that it will present Phase 3 data from the TOURMALINE-MM1 ixazomib clinical trial at the 57th American Society of Hematology (ASH) Annual Meeting to be held in Orlando, Florida from December 5 to 8, 2015.

6 Nov 2015

Novel genetic therapy treats ‘incurable’ leukaemia

A new treatment that involves editing DNA has been used for the first time at Great Ormond Street Hospital to successfully treat drug-resistant leukaemia.

6 Nov 2015

Mucus plays important role in defending invaders

By licking a wound it heals faster - this is not simply popular belief, but scientifically proven. Our saliva consists of water and mucus, among other things, and the mucus plays an important role. It stimulates white blood cells to build a good defence against invaders, according to a group of researchers at Lund University in Sweden together with colleagues from Copenhagen and Odense in Denmark.

6 Nov 2015

Seven researchers win 2015 Early Career Researcher UK Awards

The UK is a world-leader in breakthrough scientific discoveries, and seven of the early career researchers leading this field have been recognised for their contributions to areas including malaria elimination, securing water supplies for future generations and empowering patients in the management of their own health care.

6 Nov 2015

City of Hope awarded NIH grant to study potential link between environmental factors and breast cancer

The National Institutes of Health has awarded City of Hope a five-year, $4.8 million grant to study the possible role of chemicals in the environment in the development of breast cancer during the menopausal transition in women.

6 Nov 2015

Weight-loss surgery may be safe for managing type 2 diabetes in patients with mild obesity

Weight-loss surgery, long considered a treatment largely reserved for people with severe obesity, may also be a good and safe option for the treatment of uncontrolled type 2 diabetes in those who are overweight or have mild to moderate obesity, according to researchers from Cleveland Clinic in Ohio.

6 Nov 2015

Stem-cell scientists discover new view of how human blood is made

Stem-cell scientists led by Dr. John Dick have discovered a completely new view of how human blood is made, upending conventional dogma from the 1960s.

6 Nov 2015

Two genetic variants interact to alter the brain responses to high-calorie foods

For the first time, researchers have identified two genetic variants that interact to alter the brain responses to high-calorie foods, a tie that could aid in the development of targeted treatments for obesity and overweight. Researchers at Imperial College London led by Tony Goldstone, MD, PhD, of Consultant Endocrinologist, found that two gene variants - FTO and DRD2 - influenced activity in the brain reward system when looking at pictures of high-calorie foods.

6 Nov 2015

Utah chemists devise new way to detect DNA damage

University of Utah chemists devised a new way to detect chemical damage to DNA that sometimes leads to genetic mutations responsible for many diseases, including various cancers and neurological disorders.

6 Nov 2015

Researchers identify seven genetic risk loci involved in atopic march

There's a typical "career" for some allergic people, and it starts very early on the skin: babies develop atopic dermatitis, food allergies may follow, then comes asthma and later on hay fever. A group of scientists led by Ingo Marenholz and Young-Ae Lee at the Max Delbrück Center for Molecular Medicine in the Helmholtz Association, working with colleagues from several institutions, has now identified seven genetic risk loci for this course of disease.

6 Nov 2015

Scientists discover small molecule that can block growth of BRCA-deficient cancer cells

Cancer cells with mutations in BRCA1 or BRCA2 genes, which serve a vital role in preserving the integrity of the genetic code, are key targets for cancer therapeutics. Yet, few agents can selectively eliminate cells deficient in BRCA, and none can do so without the risk of inducing drug resistance.

6 Nov 2015

Study raises concerns about patient access to specialists within insurance plans under ACA

While 12 million Americans are enrolled in health care networks through the Affordable Care Act's (ACA) insurance marketplace, a recent study in the Journal of the American Medical Association raises concerns about patient access to specialists within these insurance plans.

6 Nov 2015

Sleep loss reduces insulin sensitivity, increases diabetes risk

A new study by the University of Colorado shows that the longer people are awake during the time their biological clock is telling them to sleep the worse their sensitivity to insulin, which is a precursor to diabetes.

6 Nov 2015

New tool could help identify patients most likely to benefit from chemoprevention

A team of scientists, led by researchers at University of California, San Diego Moores Cancer Center and The University of Texas MD Anderson Cancer Center, report that a genetic biomarker called loss of heterozygosity or LOH is able to predict which patients with premalignant mouth lesions are at highest risk of developing oral cancer.

6 Nov 2015

Medical Research News

Energy drink consumption linked with serious cardiovascular events

Novartis’ Cosentyx® show no progression in spinal damage in 80% of ankylosing spondylitis patients

Major US healthcare database has missing pieces

St. Michael's Hospital study finds that cholesterol-reducing diet also lowers blood pressure

NTU Singapore scientists harness dead bacteria to destroy colon tumours cells effectively

Combatting viral and bacterial lung infections with volatile anesthetics: an interview with Dr Chakravarthy

Ixazomib’s phase 3 study in relapsed/refractory multiple myeloma presented

Novel genetic therapy treats ‘incurable’ leukaemia

Mucus plays important role in defending invaders

Seven researchers win 2015 Early Career Researcher UK Awards

City of Hope awarded NIH grant to study potential link between environmental factors and breast cancer

Weight-loss surgery may be safe for managing type 2 diabetes in patients with mild obesity

Stem-cell scientists discover new view of how human blood is made

Two genetic variants interact to alter the brain responses to high-calorie foods

Utah chemists devise new way to detect DNA damage

Researchers identify seven genetic risk loci involved in atopic march

Scientists discover small molecule that can block growth of BRCA-deficient cancer cells

Study raises concerns about patient access to specialists within insurance plans under ACA

Sleep loss reduces insulin sensitivity, increases diabetes risk

New tool could help identify patients most likely to benefit from chemoprevention

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