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ORT incidence increases in nAMD despite anti-VEGF treatment

Swiss researchers report that patients with neovascular age-related macular degeneration (nAMD) experience increased incidence of outer retinal tubulation over time, despite treatment with a vascular endothelial growth factor blocker.

30 Jun 2015

Poor sleep linked to negative mood in women with bipolar disorder

Poor sleep is associated with negative mood in women with bipolar disorder, according to researchers at Penn State College of Medicine and University of Michigan Medical School.

30 Jun 2015

Tree nut consumption associated with lower body weight and lower risk of obesity

In a study published this week in Nutrition Journal*, researchers compared risk factors for heart disease and metabolic syndrome of tree nut consumers versus those who did not consume tree nuts. Tree nut (almonds, Brazil nuts, cashews, hazelnuts, macadamias, pecans, pine nuts, pistachios and walnuts) consumption was associated with lower body mass index (p=0.004), systolic blood pressure (p=0.001), insulin resistance (p=0.043) and higher levels of high-density lipoprotein-cholesterol (good cholesterol) (p=0.022).

30 Jun 2015

UC San Diego epidemiologist receives $1.5 million grant for research on HIV, substance abuse

Dan Werb, PhD, an internationally noted epidemiologist at University of California, San Diego School of Medicine, has been named one of four inaugural recipients of the Avenir Award, a prestigious $1.5 million research grant from the U.S. National Institute on Drug Abuse, part of the National Institutes of Health (NIH).

30 Jun 2015

Study supports need for diagnostic analysis of germline and tumor biomarker information

A core tenet of precision medicine is that predictive biomarkers can enhance therapeutic decision-making. In a new pilot study, scientists at Molecular Health analyzed a randomly selected set of 250 patients with solid tumors and detected predictive biomarkers in more than 85% of tumors.

30 Jun 2015

Kalorama Information: NGS diagnostics can detect any number of genetic variants

Next generation sequencing may be able to bypass some of the downside of molecular testing and in doing so earn its place in clinical testing, according to Kalorama Information.

30 Jun 2015

TSRI scientists find five different miRNAs involved in memory formation

Scientists from the Florida campus of The Scripps Research Institute (TSRI) have found that a type of genetic material called “microRNA” plays surprisingly different roles in the formation of memory in animal models. In some cases, these RNAs increase memory, while others decrease it.

30 Jun 2015

Hepatic ALT flares linked to HBsAg clearance

Hepatic alanine aminotransferase flares are associated with rapid decline and greater annual reductions of hepatitis B surface antigen in patients with chronic hepatitis B virus infection who achieve HBsAg seroclearance, say Japanese researchers.

30 Jun 2015

dlDNA marks progression of HBV-related liver disease

The level of serum duplex-linear DNA increases markedly with liver disease progression and development of hepatocellular carcinoma in patients with chronic hepatitis B virus (HBV) infection, suggests research published in Gut.

30 Jun 2015

Researchers explore why some mutations can cause severe disease in humans, but benign in animals

Researchers at Duke University School of Medicine and Brigham and Women's Hospital, Harvard Medical School have identified a mechanism that explains why some mutations can be disease-causing in one genome but benign in another.

30 Jun 2015

Imperial College London researchers discover new inherited form of obesity, type 2 diabetes

Scientists have discovered a new inherited form of obesity and type 2 diabetes in humans. A large number of genes are involved in regulating body weight, and there are now over 30 genes known in which people with harmful changes in DNA sequence become extremely overweight. Similarly, there are a number of genes that can, when altered, cause type 2 diabetes. These conditions are inherited through families in exactly the same way as disorders such as cystic fibrosis or Huntington's disease.

30 Jun 2015

Three National Laureates selected for 2015 Blavatnik National Awards for Young Scientists

A chemist who has made important discoveries in both the human brain and sustainable energy, a neurosurgeon who has done pioneering work mapping the "blueprint" of how humans speak and hear, and a computer scientist who has changed our understanding of the capacity of wireless networks are the three winners of the 2015 Blavatnik National Awards for Young Scientists.

30 Jun 2015

Majority of men who use violence against female partner struggle with serious mental health issues

The majority of men who use violence towards their partner struggle with serious mental health issues. We need to look at more than just the power relations between the sexes in order to understand and prevent domestic violence, says researcher.

30 Jun 2015

Bournemouth University researchers examine effect of lower-limb prosthetics on competitive running

Researchers at Bournemouth University have been looking at the impact of lower-limb prosthetics on competitive running, specifically looking at whether athletes with prosthesis are at an unfair advantage when running against athletes without prosthetics.

30 Jun 2015

Researchers compare relationship between marital status and body mass index in nine European countries

It is generally assumed that marriage has a positive influence on health and life expectancy. But does this "marriage bonus" also apply to the health indicator of body weight? Researchers at the University of Basel and the Max Planck Institute for Human Development have investigated this question in cooperation with the market research institute GfK. Specifically, they compared the body mass index of married couples with that of singles in nine European countries.

30 Jun 2015

Egalet reports top-line results from Category 3 HAL study of Egalet-002

Egalet Corporation, a fully integrated specialty pharmaceutical company focused on developing, manufacturing and marketing innovative pain treatments, today announced top-line results from a Category 3 human abuse liability (HAL) study of Egalet-002, an abuse-deterrent, extended-release, oral oxycodone product candidate in late-stage clinical development for the management of pain severe enough to require daily, around-the-clock opioid treatment and for which alternative treatments are inadequate.

30 Jun 2015

Bacterial ‘fight club’ approach effective for finding new drugs from natural sources

Creating bacterial "fight clubs" is an effective way to find new drugs from natural sources. That is the conclusion of a team of Vanderbilt chemists who have been exploring ways to get bacteria to produce biologically active chemicals that they normally hold in reserve. These compounds are called secondary metabolites.

30 Jun 2015

New study examines how reasons for illicit marijuana use relate to use of other drugs

Marijuana is the most prevalent drug in the U.S. Approximately 70% of the 2.8 million individuals who initiated use of illicit drugs in 2013 reported that marijuana was their first drug.

30 Jun 2015

Improved medicine packaging designs increase caregivers' willingness to provide ORS to children

The usage of key medicines in developing countries could be significantly increased through improved packaging appearance, a new study by the Clinton Health Access Initiative, Inc. (CHAI) and the University of Warwick finds.

30 Jun 2015

New study sheds light on the effects of marijuana on weight gain in young adults

While cannabis alters the functions of neurobiological circuits controlling appetite, its effect on weight gain is complex since several factors appear to be involved, says Didier Jutras-Aswad, University of Montreal professor and researcher at the CHUM Research Centre. "It is known - and often reported by users - that cannabis causes temporary increase in appetite.

30 Jun 2015

Medical Research News

ORT incidence increases in nAMD despite anti-VEGF treatment

Poor sleep linked to negative mood in women with bipolar disorder

Tree nut consumption associated with lower body weight and lower risk of obesity

UC San Diego epidemiologist receives $1.5 million grant for research on HIV, substance abuse

Study supports need for diagnostic analysis of germline and tumor biomarker information

Kalorama Information: NGS diagnostics can detect any number of genetic variants

TSRI scientists find five different miRNAs involved in memory formation

Hepatic ALT flares linked to HBsAg clearance

dlDNA marks progression of HBV-related liver disease

Researchers explore why some mutations can cause severe disease in humans, but benign in animals

Imperial College London researchers discover new inherited form of obesity, type 2 diabetes

Three National Laureates selected for 2015 Blavatnik National Awards for Young Scientists

Majority of men who use violence against female partner struggle with serious mental health issues

Bournemouth University researchers examine effect of lower-limb prosthetics on competitive running

Researchers compare relationship between marital status and body mass index in nine European countries

Egalet reports top-line results from Category 3 HAL study of Egalet-002

Bacterial ‘fight club’ approach effective for finding new drugs from natural sources

New study examines how reasons for illicit marijuana use relate to use of other drugs

Improved medicine packaging designs increase caregivers' willingness to provide ORS to children

New study sheds light on the effects of marijuana on weight gain in young adults

Transforming Cardiovascular Care: Insights from Mina Makar at AstraZeneca

Clue's CEO Rhiannon White on the Future of Femtech and PCOS

Freezing Point Osmometry in Life Science Applications

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