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UAlberta scientists explore physical principles underlying formation of misfolded protein aggregates

Working towards the ultimate goal to develop therapeutics to treat diseases such as Alzheimer's, Parkinson's, ALS, and BSE (Mad Cow Disease), University of Alberta scientists Michael Woodside, Hao Yu, and Derek Dee are investigating the physical principles underlying the formation of misfolded protein aggregates.

26 Jun 2015

Growth of lymph node metastases takes advantage of existing blood vessels

While the use of antiangiogenesis drugs that block the growth of new blood vessels can improve the treatment of some cancers, clinical trials of their ability to prevent the development of new metastases have failed. Now a study from the Massachusetts General Hospital Cancer Center may have found at least one reason why.

26 Jun 2015

Malaria parasite protein essential for parasite invasion into red blood cells

A new study led by researchers at Harvard T.H. Chan School of Public Health finds that a malaria parasite protein called calcineurin is essential for parasite invasion into red blood cells. Human calcineurin is already a proven target for drugs treating other illnesses including adult rheumatoid arthritis and lupus, and the new findings suggest that parasite calcineurin should be a focus for the development of new antimalarial drugs.

26 Jun 2015

New study reveals key part of Ebola virus life cycle at higher resolution than ever before

A new study led by scientists at The Scripps Research Institute (TSRI) reveals a key part of the Ebola virus life cycle at a higher resolution than ever before. The research sheds light on how Ebola virus assembles—and how researchers might stop the often-fatal infection.

26 Jun 2015

IU researchers find that microRNA-29 may be potent therapeutic target against pancreatic cancer

Indiana University cancer researchers found that a particular microRNA may be a potent therapeutic agent against pancreatic cancer. The research was published June 22 in the journal Scientific Reports.

26 Jun 2015

Animal study highlights major safety concern regarding use of MRI contrast agents in patients

New results in animals highlight a major safety concern regarding a class of magnetic resonance imaging (MRI) contrast agents used in millions of patients each year, according to a paper published online by the journal Investigative Radiology.

26 Jun 2015

New chemical compound reduces pancreatic cancer tumour growth by 80% in mice

Scientists from UCL (University College London) have designed a chemical compound that has reduced the growth of pancreatic cancer tumours by 80 percent in treated mice.

26 Jun 2015

Light may just be the answer for solving sleep problems among lung cancer patients

When you're having trouble sleeping, light is the last thing you assume you need. But according to a pilot study attempting to solve insomnia among lung cancer patients led by University at Buffalo sleep researcher Grace Dean, light may just be the answer.

26 Jun 2015

Lund University research questions the doctrine on how the brain recognizes and processes information

New research from Lund University in Sweden questions the prevailing doctrine on how the brain absorbs and processes information. The idea that the brain has a mechanism to maintain activity at the lowest possible level is incorrect.

26 Jun 2015

Fructose stimulates reward system in the brain to a lesser degree than glucose

Fructose not only results in a lower level of satiety, it also stimulates the reward system in the brain to a lesser degree than glucose. This may cause excessive consumption accompanied by effects that are a risk to health, report researchers from the University of Basel in a study published in the scientific journal PLOS ONE. Various diseases have been attributed to industrial fructose in sugary drinks and ready meals.

26 Jun 2015

Experimental new treatment approach can send deadly leukemia into remission

An experimental new treatment approach for a rare, deadly leukemia can send the disease into remission even in patients for whom the standard therapy has failed, buying them more time to have the stem cell transplant that could save their lives, a small pilot study has found.

26 Jun 2015

New QUT research confirms that friends influence alcohol consumption

Friends can be a dangerous influence, with new QUT research confirming what many drinkers already know - that drinking with mates can push you to drink more.

26 Jun 2015

Pilot antibiotic program at pediatric long-term care facility decreases use of topical antibiotic

A pilot antibiotic stewardship program at a pediatric long-term care facility brought about a 59 percent decrease in use of a topical antibiotic and an 83 percent decrease in orders for antibiotics without proper documentation during a six-month period, according to a new study.

26 Jun 2015

University of Pittsburgh surgeon receives Anthony Cerami Award in Translational Medicine

The Feinstein Institute for Medical Research and Molecular Medicine announced today that the fourth Anthony Cerami Award in Translational Medicine will be conferred to Thomas E. Starzl, MD, PhD, professor of surgery at the University of Pittsburgh School of Medicine. The award is in recognition of his research in organ transplantation and alloengraftment mechanisms.

26 Jun 2015

QUT researcher reveals how compulsive snacking can be a major cause of weight gain

A QUT researcher has had an article on how compulsive snacking is a major cause of weight gain published in the international journal Eating Behaviors.

26 Jun 2015

Artificial blood technology may help fight disease-transmitting mosquitoes in resource-limited areas

A "nuisance" is probably one of the nicest things people call mosquitoes. Mosquitoes have been called the deadliest animal on the planet, because of the diseases they spread.

26 Jun 2015

Alabama scientists show how phytochemical in magnolia works against head and neck cancers

Magnolias are prized for their large, colorful, fragrant flowers. Does the attractive, showy tree also harbor a potent cancer fighter?

26 Jun 2015

E2F4 biomarker can help predict prognosis and response to BCG therapy in bladder cancer

Investigators from Dartmouth's Norris Cotton Cancer Center harnessed genomic data to discover that the previously identified E2F4 signature in breast cancer can be utilized to predict prognosis and response to therapy in bladder cancer.

25 Jun 2015

Long-acting injectable antipsychotic medication benefits people with schizophrenia

Schizophrenia, which affects 2 million to 3 million people in the U.S., causes hallucinations, delusions and disorganization. Left untreated, the disease can cause a significant loss in quality of life, including unemployment and estrangement from loved ones. But many people with schizophrenia can control the disorder and live without symptoms for several years if they consistently take prescribed antipsychotic medication, typically a daily pill.

25 Jun 2015

UIC researchers identify molecular mechanism that directs embryonic stem cells to turn into endothelial cells

Researchers at the University of Illinois at Chicago have identified a molecular mechanism that directs embryonic stem cells to mature into endothelial cells -- the specialized cells that form blood vessels. Understanding the processes initiated by this mechanism could help scientists more efficiently convert stem cells into endothelial cells for use in tissue repair, or for engineering blood vessels to bypass blockages in the heart.

25 Jun 2015

Medical Research News

UAlberta scientists explore physical principles underlying formation of misfolded protein aggregates

Growth of lymph node metastases takes advantage of existing blood vessels

Malaria parasite protein essential for parasite invasion into red blood cells

New study reveals key part of Ebola virus life cycle at higher resolution than ever before

IU researchers find that microRNA-29 may be potent therapeutic target against pancreatic cancer

Animal study highlights major safety concern regarding use of MRI contrast agents in patients

New chemical compound reduces pancreatic cancer tumour growth by 80% in mice

Light may just be the answer for solving sleep problems among lung cancer patients

Lund University research questions the doctrine on how the brain recognizes and processes information

Fructose stimulates reward system in the brain to a lesser degree than glucose

Experimental new treatment approach can send deadly leukemia into remission

New QUT research confirms that friends influence alcohol consumption

Pilot antibiotic program at pediatric long-term care facility decreases use of topical antibiotic

University of Pittsburgh surgeon receives Anthony Cerami Award in Translational Medicine

QUT researcher reveals how compulsive snacking can be a major cause of weight gain

Artificial blood technology may help fight disease-transmitting mosquitoes in resource-limited areas

Alabama scientists show how phytochemical in magnolia works against head and neck cancers

E2F4 biomarker can help predict prognosis and response to BCG therapy in bladder cancer

Long-acting injectable antipsychotic medication benefits people with schizophrenia

UIC researchers identify molecular mechanism that directs embryonic stem cells to turn into endothelial cells

Transforming Cardiovascular Care: Insights from Mina Makar at AstraZeneca

Clue's CEO Rhiannon White on the Future of Femtech and PCOS

Freezing Point Osmometry in Life Science Applications

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