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Children with congenital heart disease and ADHD can benefit from stimulant medications

A new study finds that children with congenital heart disease and ADHD can take stimulant medications without fear of significant cardiovascular side effects.

5 Oct 2015

Calcitonin-gene related peptide antibody inhibition shows migraine prevention promise

TEV-48125, a monoclonal anti-calcitonin-gene related peptide antibody, is well tolerated and effective in the prevention of high-frequency episodic migraine and chronic migraine, findings from two phase IIb studies show.

2 Oct 2015

Anteroinferior encephalocele a rare but important epilepsy cause

Clinicians should actively search for anteroinferior encephaloceles in patients with treatment-refractory epilepsy, say researchers.

2 Oct 2015

Preoperative MRI use increasing in breast cancer

A Canadian research team reports a substantial increase in the use of preoperative magnetic resonance imaging over a 10-year period in women with newly diagnosed breast cancer.

2 Oct 2015

6-minute walk ‘not an accurate surrogate’ in systemic sclerosis-associated PAH

The 6-minute walk distance of patients with systemic sclerosis-associated pulmonary arterial hypertension is not a suitable marker for tracking treatment-related haemodynamic changes, say researchers.

2 Oct 2015

Height may be linked to cancer risk

Taller individuals are more likely to develop cancer than shorter people, according to the results of a study presented at the 54th Annual European Society for Pediatric Endocrinology Meeting in Barcelona.

2 Oct 2015

New test capable of detecting all viruses that affect people and animals

A new, super-sensitive test has been developed that can detect virtually any virus that causes illness in humans and animals, according to researchers at Washington University School of Medicine in St. Louis.

1 Oct 2015

No lasting metabolic health costs from combined GH and GnRH analogue therapy

Gonadotropin-releasing hormone analogue given alongside growth hormone during puberty in order to increase adult height does not have long-term metabolic health consequences in children born small for gestational age, research shows.

1 Oct 2015

Quitting smoking may delay secondary progressive MS onset

Patients who are smokers when diagnosed with relapsing–remitting multiple sclerosis may be able to delay the time to onset of progressive disease by quitting smoking, a study suggests.

1 Oct 2015

Neuroendocrine sequelae common after paediatric optic gliomas

Neuroendocrine sequelae are common following paediatric low-grade gliomas affecting the optic pathway, hypothalamus and suprasellar areas and are influenced by tumour location and treatment choice, a study shows.

1 Oct 2015

HLA-DPB1 regulatory region genotype predicts acute GVHD

Analysis of a HLA-DPB1 regulatory region variant has shed light on the risk of acute graft-versus-host disease in patients undergoing haematopoietic cell transplantation from an unrelated donor.

1 Oct 2015

Chromosome 3q26.2 rearrangements linked to poor CML prognosis

Rearrangements of chromosome 3q26.2 have a significant negative impact on patients with chronic myeloid leukaemia, suggests research published in Blood.

1 Oct 2015

Self-reported fatigue predicts myelodysplastic syndromes survival

Patient-reported fatigue severity is an independent prognostic marker for survival in patients with newly diagnosed intermediate-2- or high-risk myelodysplastic syndromes, according to research published in The Lancet Oncology.

1 Oct 2015

Beta-catenin shows treatment target potential for TKI-resistant CML

Nuclear β-catenin could be a treatment target for patients whose chronic myeloid leukaemia is resistant to tyrosine kinase inhibitors independent of additional BCR–BL1 mutations, US researchers suggest.

1 Oct 2015

Early genetic diagnosis in neonatal diabetes a ‘new framework for clinical care’

Early genetic testing of babies with suspected neonatal diabetes identifies the underlying cause in more than 80% of cases, say researchers.

1 Oct 2015

Short bursts of high intensity exercise may improve cardiovascular health in teens

Adolescents who perform just eight to ten minutes of high-intensity interval exercise three times a week could be significantly reducing their risk of developing heart conditions, new research has concluded.

1 Oct 2015

Minor infections, inadequate vaccinations increase stroke risk in children

Children who have suffered recent infections or have not received most or all of their vaccinations are at a higher risk for stroke, according to research published in the Sept. 30 issue of Neurology, the medical journal of the American Academy of Neurology.

1 Oct 2015

Experimental drug shows promise in mice with multiple sclerosis

An experimental drug originally identified in a National Cancer Institute library of chemical compounds as a potential therapy for brain and basal cell cancers improves the symptoms of mice with a form of the debilitating neurological disorder multiple sclerosis (MS), according to new research from NYU Langone Medical Center.

1 Oct 2015

Weight training can make a big difference for breast cancer survivors

Weight training can be a big boost to breast cancer survivors who are trying to regain muscle and bone strength lost due to cancer treatment and physical inactivity, says a Florida State University researcher.

1 Oct 2015

Vanderbilt study reveals benefits of theatre-based program in children with autism

Children with autism who participated in a 10-week, 40-hour, theatre-based program showed significant differences in social ability compared to a group of children with autism who did not participate, according to a Vanderbilt study published in the Journal of Autism and Developmental Disorders.

1 Oct 2015