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UVA scientists find blueprint for combating human disease using DNA clad in near-indestructible armor

By unlocking the secrets of a bizarre virus that survives in nearly boiling acid, scientists at the University of Virginia School of Medicine have found a blueprint for battling human disease using DNA clad in near-indestructible armor.

27 May 2015

Study reveals molecular basis for endocrine therapy-resistant breast cancer

Mitsuyoshi Nakao, Director of the Institute of Molecular Embryology and Genetics in Kumamoto University and Associate Professor Noriko Saitoh revealed that a cluster of defined, non-coding RNAs are mechanistically involved in endocrine therapy resistance in human breast cancer cells. Furthermore, resveratrol, a kind of polyphenol, was found to repress these RNAs and inhibit the proliferative activity of breast cancer cells which had acquired resistance.

27 May 2015

Study: Drugs that block NPC1 protein could be used to treat Ebola virus disease

A new study has demonstrated that a protein called Niemann-Pick C1 (NPC1) is critical for the Ebola virus to infect a host. The study, published in the May/June issue of mBio, the online open-access journal of the American Society for Microbiology, suggests that drugs that block NPC1 could be used to treat this deadly disease.

27 May 2015

IU research finds that air pollution regulations have uncertain health effects

Air pollution regulations issued by the U.S. Environmental Protection Agency are estimated to save thousands of lives annually. A new study by researchers at Indiana University says these estimates are more uncertain than commonly believed.

27 May 2015

Researchers make important breakthrough in identifying major drivers of excessive coughing

Cough treatments could change dramatically after the herpes virus helped researchers discover that the respiratory tract links to two different parts of the nervous system.

27 May 2015

Risk for obesity-associated diseases significantly higher for males than females

Obesity may be tougher on male immune systems than females, a new study in mice at the University of Michigan Medical School suggests.

27 May 2015

Mediterranean-style diet can reduce womb cancer risk by half

Women who eat a Mediterranean diet could cut their risk of womb cancer by more than half (57 per cent), according to a study published today (Wednesday) in the British Journal of Cancer.

27 May 2015

Alternative generic strategy for breast cancer treatment

Maxing out the inherently stressed nature of treatment-resistant breast cancer cells thwarts their adaptive ability to evolve genetic workarounds to treatment, a new study suggests.

27 May 2015

Versatile paediatric standing frame to be launched at Kidz South

Standing involves many different positions and a child might want to stand prone (tilted forward), upright or supine (supported from behind) and although each position offers specific benefits, they all offer greater weight bearing through a child’s legs which helps to strengthen bones...

26 May 2015

Breastfeeding duration and intelligence: an interview with Dr Bernardo Lessa Horta

Our research shows a benefit of breastfeeding on performance in IQ tests that was similar to the benefit reported in previous tests among children and adolescents, suggesting that the benefits of breastfeeding are still observed in adulthood...

26 May 2015

Alizé Pharma presents clinical results from the AZP-531 program at the ADA 75th Scientific Sessions

Detailed data will be presented from the two Phase I trials conducted in 76 healthy volunteers and overweight or obese subjects...

26 May 2015

Commuting stress factors can lead to burnout

Commuting length, distance, and means are stress factors that can lead to burnout, says Annie Barreck of the University of Montreal's School of Industrial Relations. "A correlation exists between commuting stress factors and the likelihood of suffering from burnout.

26 May 2015

Study indicates that arthritis patients may not be taking medication as regularly as prescribed

Researchers from the Arthritis Research UK Centre for Epidemiology at The University of Manchester found that 40% of patients scored low on an adherence questionnaire at least once during their time in a recent study, indicating that they might not be taking their expensive biological therapies as regularly as prescribed.

26 May 2015

AXT to distribute OpenSpecimen Biobanking software solution

Based on an open source platform designed by Krishagni Solutions, OpenSpecimen (formerly known as caTissue Plus) is currently used by a host of highly-respected research institutions across 12 countries where it manages biospecimens from collection to utilisation...

From AXT Pty Ltd 26 May 2015

UC Davis researchers show feasibility of using statins to treat asthma

Statins continue to show that their benefits extend beyond their original focus of lowering high cholesterol. With the increasing prevalence of asthma, scientists are studying the effects of statins in the lungs.

26 May 2015

Researchers find way to prevent, reduce or delay cannabis use amongst at-risk youth

Responding to rapidly shifting legal and cultural environments, researchers at the University of Montreal and CHU Sainte-Justine Children's Hospital have found a way to prevent, reduce or delay cannabis use amongst some at-risk youth. Cannabis users are at risk of neurocognitive deficits, reduced educational and occupational attainment, motor vehicle accidents, exacerbation of psychiatric symptoms, and precipitation of psychosis.

26 May 2015

Study could offer new way to treat, prevent diabetes-associated blindness

Reporting on their study with lab-grown human cells, researchers at The Johns Hopkins University and the University of Maryland say that blocking a second blood vessel growth protein, along with one that is already well-known, could offer a new way to treat and prevent a blinding eye disease caused by diabetes.

26 May 2015

Removing accumulated mutant p53 protein regresses tumors, increases cancer survival

Removing accumulated mutant p53 protein from a cancer model showed that tumors regress significantly and survival increases. This finding, by an international team of cancer researchers led by Ute Moll, MD, Professor of Pathology at Stony Brook University School of Medicine, is reported in a paper published advanced online May 25 in Nature.

26 May 2015

Researchers identify six mRNA isoforms that could be used to diagnose early-stage ovarian cancer

Ovarian cancer is notoriously difficult to diagnose and treat, making it an especially fatal disease. Researchers at University of California, San Diego School of Medicine and Moores Cancer Center have now identified six mRNA isoforms (bits of genetic material) produced by ovarian cancer cells but not normal cells, opening up the possibility that they could be used to diagnose early-stage ovarian cancer.

26 May 2015

Study reveals how attitudes, beliefs of cancer patients drive complementary and alternative medicine use

A new study has shed light on how cancer patients' attitudes and beliefs drive the use of complementary and alternative medicine. Published early online in CANCER, a peer-reviewed journal of the American Cancer Society, the findings may help hospitals develop more effective and accessible integrative oncology services for patients.

26 May 2015

Medical Research News

UVA scientists find blueprint for combating human disease using DNA clad in near-indestructible armor

Study reveals molecular basis for endocrine therapy-resistant breast cancer

Study: Drugs that block NPC1 protein could be used to treat Ebola virus disease

IU research finds that air pollution regulations have uncertain health effects

Researchers make important breakthrough in identifying major drivers of excessive coughing

Risk for obesity-associated diseases significantly higher for males than females

Mediterranean-style diet can reduce womb cancer risk by half

Alternative generic strategy for breast cancer treatment

Versatile paediatric standing frame to be launched at Kidz South

Breastfeeding duration and intelligence: an interview with Dr Bernardo Lessa Horta

Alizé Pharma presents clinical results from the AZP-531 program at the ADA 75th Scientific Sessions

Commuting stress factors can lead to burnout

Study indicates that arthritis patients may not be taking medication as regularly as prescribed

AXT to distribute OpenSpecimen Biobanking software solution

UC Davis researchers show feasibility of using statins to treat asthma

Researchers find way to prevent, reduce or delay cannabis use amongst at-risk youth

Study could offer new way to treat, prevent diabetes-associated blindness

Removing accumulated mutant p53 protein regresses tumors, increases cancer survival

Researchers identify six mRNA isoforms that could be used to diagnose early-stage ovarian cancer

Study reveals how attitudes, beliefs of cancer patients drive complementary and alternative medicine use

Transforming Cardiovascular Care: Insights from Mina Makar at AstraZeneca

Clue's CEO Rhiannon White on the Future of Femtech and PCOS

Freezing Point Osmometry in Life Science Applications

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