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CHLA researchers develop new protein-based therapy against drug-resistant leukemia cells

Resistance of leukemia cells to contemporary chemotherapy is one of the most formidable obstacles to treating acute lymphoblastic leukemia (ALL), the most common form of childhood cancer. Now researchers at Children's Hospital Los Angeles have designed and developed a new protein-based therapy they believe will prove highly effective against drug-resistant leukemia cells.

27 Jan 2015

Study shows differences in play behavior, brain activation patterns and stress levels in autistic children

Brain scans confirm significant differences in play behavior, brain activation patterns and stress levels in children with autism spectrum disorder (ASD) as compared with typically developing children.

27 Jan 2015

Study: Poor psychosocial work environment linked to cardiovascular problems

A psychosocially poor work environment means that employees experience highly demanding requirements but have little ability to control their work or not feel sufficiently appreciated for the contributions they make.

27 Jan 2015

Deprived, ethnic minority areas in England worst affected by air pollution

A new study has found big differences in air pollution across communities in England, with deprived and ethnic minority areas the worst affected.

27 Jan 2015

Majority of Canada's homeless adults with mental illness show evidence of cognitive deficits

Nearly three-quarters of homeless adults with mental illness in Canada show evidence of cognitive deficits, such as difficulties with problem solving, learning and memory, new research has found.

27 Jan 2015

Pitt researchers receive NIH grant to improve health of sedentary, overweight people

University of Pittsburgh Graduate School of Public Health researchers are flipping conventional thought on its head regarding how to improve the health of sedentary people at risk for diabetes and heart disease in a new study designed to combat a condition popularly called "sitting disease."

27 Jan 2015

Increased levels of stress hormones in mother can affect foetal development

Increased levels of stress hormones can lead pregnant mice to overeat, but affect growth of the foetus and, potentially, the long term health of her offspring, according to a study published today.

27 Jan 2015

Researchers decode how cancer uses cell-cell interaction mechanism to promote metastasis

Cancer uses a little-understood element of cell signaling to hijack the communication process and spread, according to Rice University researchers.

27 Jan 2015

Upregulating heme-oxygenase with hemin helps improve pericardial adipocyte morphology, function

Scientists at the University of Saskatchewan College of Medicine, Department of Physiology, Saskatoon, Canada, led by Dr. Joseph Fomusi Ndisang have determined that upregulating heme-oxygenase with hemin improves pericardial adipocyte morphology and function.

27 Jan 2015

Imperial College professor honored with Helmholtz International Fellow Award

The British cell biologist Professor Amanda Gay Fisher of Imperial College London has been honored with the Helmholtz International Fellow Award for her excellent research. Fisher is one of seven outstanding researchers from abroad who received the award, each of which is endowed with 20,000 euros. According to the Helmholtz Association, Germany's largest scientific organization, the award also includes an invitation to visit one or several Helmholtz research centers.

27 Jan 2015

Researchers find methods to manipulate natural proteins that self-assemble into amyloid fibrils

Nature has many examples of self-assembly, and bioengineers are interested in copying or manipulating these systems to create useful new materials or devices. Amyloid proteins, for example, can self-assemble into the tangled plaques associated with Alzheimer's disease -- but similar proteins can also form very useful materials, such as spider silk, or biofilms around living cells.

27 Jan 2015

Study explores economic outcomes of hospital-based violence intervention

At more than 25 hospitals across the U.S., health care professionals have embraced a public health approach to their work--taking action to prevent violent injuries, not just treat them. In programs known as hospital-based violence intervention programs (HVIPs), teams of medical professionals, social workers and researchers step in at a critical moment in a patient's life--the period following a violent injury such as a gunshot or stab wound--with case management, counseling and other services that help these victims break free from the cycle of violence.

27 Jan 2015

Household rules, regular sleep-wake routines improve sleep in children

Children obtain better and more age-appropriate sleep in the presence of household rules and regular sleep-wake routines, according to sleep researchers.

27 Jan 2015

Morphine after tonsillectomy may be life threatening for children

Treating post-operative pain with morphine can cause life-threatening respiratory problems in some children who have had their tonsils and/or adenoids removed, new research has found.

27 Jan 2015

Progenitor cells responsible for generation and maintenance of Merkel cells

Researchers have identified a population of "progenitor" cells in the skin that are solely responsible for the generation and maintenance of touch-sensing Merkel cells. The study appears in The Journal of Cell Biology.

27 Jan 2015

Alcohol drinking pattern influences risk of cirrhosis

Approximately 170,000 people die from alcoholic cirrhosis of the liver in Europe every year. Although alcohol is the most important risk factor, less is known about the significance of different patterns of drinking. Currently scientists believe that cirrhosis is a function of the volume of alcohol consumed irrespective of patterns of drinking. Investigators have now established that alcohol drinking pattern has a significant influence on the risk of cirrhosis and that daily drinking increases that risk compared with drinking less frequently.

27 Jan 2015

Many breast cancer patients lack knowledge about their tumors

A new analysis has found that many women with breast cancer lack knowledge about their illness, with minority patients less likely than white patients to know and report accurate information about their tumors' characteristics.

27 Jan 2015

Flexible work hours may help curb sleep deficiency

Giving employees more control over their work schedules may help curb sleep deficiency, according to health researchers.

27 Jan 2015

NMR in cancer research: an interview with Andy Byrd

My research these days is generally classified as structural biology, although as I trained in chemistry. I specialize in nuclear magnetic resonance (NMR) applied to biological problems. Our lab is very interested in studying mammalian proteins, particularly systems involved in cancer, in order to try to understand mechanisms to provide that information for our collaborators, and for the general knowledge of the community as well.

From Bruker BioSpin - NMR, EPR and Imaging 26 Jan 2015

Large numbers of boys suffer from cognitive disabilities linked to lead than girls

A study recently published in the Journal of Environmental Health provides evidence the female hormones estrogen and estradiol may help ward off the effects of lead exposure for young girls, explaining why boys, in greater numbers than girls, are shown to suffer from the cognitive disabilities linked to lead.

24 Jan 2015

Medical Research News

CHLA researchers develop new protein-based therapy against drug-resistant leukemia cells

Study shows differences in play behavior, brain activation patterns and stress levels in autistic children

Study: Poor psychosocial work environment linked to cardiovascular problems

Deprived, ethnic minority areas in England worst affected by air pollution

Majority of Canada's homeless adults with mental illness show evidence of cognitive deficits

Pitt researchers receive NIH grant to improve health of sedentary, overweight people

Increased levels of stress hormones in mother can affect foetal development

Researchers decode how cancer uses cell-cell interaction mechanism to promote metastasis

Upregulating heme-oxygenase with hemin helps improve pericardial adipocyte morphology, function

Imperial College professor honored with Helmholtz International Fellow Award

Researchers find methods to manipulate natural proteins that self-assemble into amyloid fibrils

Study explores economic outcomes of hospital-based violence intervention

Household rules, regular sleep-wake routines improve sleep in children

Morphine after tonsillectomy may be life threatening for children

Progenitor cells responsible for generation and maintenance of Merkel cells

Alcohol drinking pattern influences risk of cirrhosis

Many breast cancer patients lack knowledge about their tumors

Flexible work hours may help curb sleep deficiency

NMR in cancer research: an interview with Andy Byrd

Large numbers of boys suffer from cognitive disabilities linked to lead than girls

Decoding Cannabis: Differentiating Hemp and Marijuana

Deciphering the Microbiome with The Microsetta Initiative

Leveraging the power of automation to boost research

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