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Magnetic nanoparticles may hold key to bringing immunotherapy into successful clinical use

In recent years, researchers have hotly pursued immunotherapy, a promising form of treatment that relies on harnessing and training the body's own immune system to better fight cancer and infection. Now, results of a study led by Johns Hopkins investigators suggests that a device composed of a magnetic column paired with custom-made magnetic nanoparticles may hold a key to bringing immunotherapy into widespread and successful clinical use.

16 Jul 2015

University of Bristol-led study could provide new target for treating neurological disorders

Findings, published today [15 Jul] in Nature Communications, reveal the extent a mutation associated with autism and epilepsy plays in impairing a biochemical process in the brain. The study, led by University of Bristol researchers, could provide a new target for treating neurological disorders.

16 Jul 2015

Researchers identify gene that underlies thinking skills

An international team of researchers, including investigators from the University of Mississippi Medical Center, has identified a gene that underlies healthy information processing -- a first step on a complicated road to understand cognitive aging and age-related diseases, such as Alzheimer's disease.

16 Jul 2015

Older adults can boost brain function by raising their fitness level

New research conducted at the University of Kansas Medical Center indicates that older adults can improve brain function by raising their fitness level.

16 Jul 2015

U of T researchers discover new details about key gene involved in ALS

A University of Toronto research team has discovered new details about a key gene involved in ALS, perhaps humanity's most puzzling, intractable disease.

16 Jul 2015

Salk researchers move one step closer to making cures for genetic diseases a reality

Healthy brain, muscle, eye and heart cells would improve the lives of tens of thousands of people around the world with debilitating mitochondrial diseases. Now, researchers at the Salk Institute have gotten one step closer to making such cures a reality: they've turned cells from patients into healthy, mutation-free stem cells that can then become any cell type.

16 Jul 2015

Increased risk of death during delivery for women with epilepsy

Pregnant women with epilepsy have a more than 10-fold increased risk of death during hospitalisation for delivery, show study findings that suggest the need for increased clinical attention for these pregnancies.

15 Jul 2015

Oral PAH treatments stave off clinical decline

Oral treatments for pulmonary arterial hypertension reduce patients’ risk of clinical worsening but have little effect on survival, say the authors of a meta-analysis.

15 Jul 2015

Stress Doppler echocardiography ‘reliable’ for early PAH detection in systemic sclerosis

Researchers recommend performing echocardiography at rest and during exercise to screen for pulmonary arterial hypertension in patients with systemic sclerosis.

15 Jul 2015

Severe dyskinesias rare in community Parkinson’s cohort

Motor fluctuations and dyskinesias affect about a third of community-based patients with Parkinson’s disease, but dyskinesias are rarely severe enough to warrant a change of treatment, report researchers.

15 Jul 2015

Doxorubicin omission feasible for select Wilms’ tumour patients

Stratifying patients by histological response to preoperative chemotherapy may allow some children with Wilms’ tumour to avoid doxorubicin and its associated cardiotoxicity, suggest study findings published in The Lancet.

15 Jul 2015

Researchers identify DPP9 enzyme that can regulate growth, movement of liver cancer cells

Researchers at the Centenary Institute in Sydney have uncovered new information about an enzyme called DPP9 that they believe to be a potential therapeutic target for limiting tumour growth and its ability to spread to and in the liver.

15 Jul 2015

UK investment lacking for pneumonia research

UK investment in pneumonia research is lacking when compared to spending on influenza and tuberculosis, according to a new study by the University of Southampton and University College London.

15 Jul 2015

Scientists discover new variant of streptococcal bacteria that contributes to severe infections

Scientists have discovered a new variant of streptococcal bacteria that has contributed to a rise in disease cases in the UK over the last 17 years.

15 Jul 2015

Pioneering Southampton research investigates health impacts of spaceflight

Pioneering research from the University of Southampton into the health impacts of spaceflight has been identified as a possible experiment to be conducted by British astronaut Tim Peake on his maiden voyage to the International Space Station later this year.

15 Jul 2015

New study shows high-fat diet can cause impairments in functioning of mesolimbic dopamine system

High-fat feeding can cause impairments in the functioning of the mesolimbic dopamine system, says Stephanie Fulton of the University of Montreal and the CHUM Research Centre. This system is a critical brain pathway controlling motivation. Fulton's findings, published today in Neuropsychopharmacology, may have great health implications.

15 Jul 2015

Cassiopea selects DATATRAK platform for significant global study

DATATRAK International, Inc., the leader in developing cloud-based, unified dClinical technologies and delivering related services for the clinical trials industry, today announced that Cassiopea S.p.A., the newly IPO'd former subsidiary of longtime partner Cosmo Pharmaceuticals SA has selected DATATRAK for a significant global study.

15 Jul 2015

Study: Breast cancer survivors experience post-treatment weight gain compared with cancer-free peers

Among women with a family history of breast cancer, those diagnosed with breast cancer gained weight at a greater rate compared with cancer-free women of the same age and menopausal status.

15 Jul 2015

Gene therapy provides life-long protection to photoreceptor cells in animal model of retinitis pigmentosa

A collaboration between scientists in the UK and the USA has shown that gene therapy can give life-long protection to the light-sensitive photoreceptor cells responsible for colour vision in a mouse model of the most common inherited eye disorder.

15 Jul 2015

UAB researchers find therapeutic target for treatment of acute spinal cord injuries

UAB researchers have identified a therapeutic target for the treatment of acute spinal cord injuries. According to this research, conducted on mice, the administration of a drug that prevents loss of myelin - the insulating sheath around nerve fibres that allows signals to be transmitted - increases the mobility of the mice after an injury.

15 Jul 2015

Medical Research News

Magnetic nanoparticles may hold key to bringing immunotherapy into successful clinical use

University of Bristol-led study could provide new target for treating neurological disorders

Researchers identify gene that underlies thinking skills

Older adults can boost brain function by raising their fitness level

U of T researchers discover new details about key gene involved in ALS

Salk researchers move one step closer to making cures for genetic diseases a reality

Increased risk of death during delivery for women with epilepsy

Oral PAH treatments stave off clinical decline

Stress Doppler echocardiography ‘reliable’ for early PAH detection in systemic sclerosis

Severe dyskinesias rare in community Parkinson’s cohort

Doxorubicin omission feasible for select Wilms’ tumour patients

Researchers identify DPP9 enzyme that can regulate growth, movement of liver cancer cells

UK investment lacking for pneumonia research

Scientists discover new variant of streptococcal bacteria that contributes to severe infections

Pioneering Southampton research investigates health impacts of spaceflight

New study shows high-fat diet can cause impairments in functioning of mesolimbic dopamine system

Cassiopea selects DATATRAK platform for significant global study

Study: Breast cancer survivors experience post-treatment weight gain compared with cancer-free peers

Gene therapy provides life-long protection to photoreceptor cells in animal model of retinitis pigmentosa

UAB researchers find therapeutic target for treatment of acute spinal cord injuries

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