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Effecting changes to FosB gene could help control addiction, depression

Regulation of a single, specific gene in a brain region related to drug addiction and depression is sufficient to reduce drug and stress responses, according to a study conducted at the Icahn School of Medicine at Mount Sinai and published October 27 online in the journal Nature Neuroscience.

12 Nov 2014

Pretreatment ILD is a risk factor for developing radiation pneumonitis in stage I NSCLC patients

Pretreatment interstitial lung disease (ILD) is a significant risk factor for developing symptomatic and severe radiation pneumonitis in stage I non-small cell lung cancer (NSCLC) patients treated with stereotactic body radiation therapy (SBRT) alone.

12 Nov 2014

Research opens new potential target against enterics

In research published in Nature Chemical Biology, scientists from RIKEN in Japan have discovered a surprisingly simple mechanism through which enterics can adjust to the very different oxygen environments inside the human gut and outside.

12 Nov 2014

Scientists identify new therapeutic targets, screening test to uncover compounds for memory disorders

In a pair of related studies, scientists from the Florida campus of The Scripps Research Institute have identified a number of new therapeutic targets for memory disorders and have developed a new screening test to uncover compounds that may one day work against those disorders.

12 Nov 2014

RPCI researchers identify two novel candidate prognostic markers for ovarian cancer

Cancer researchers at Roswell Park Cancer Institute have identified two independent classes of novel candidate prognostic markers for ovarian cancer, advancing efforts to develop targeted therapies for the disease. The findings resulted from two separate studies published in the peer-reviewed journal PLoS ONE and based on data from The Cancer Genome Atlas (TCGA), the world's largest public database on gene expression in different tumor types.

12 Nov 2014

Enterome, AbbVie to develop novel diagnostic products, therapies for microbiome-related diseases

ENTEROME Bioscience SA, a pioneer in the development of therapeutic solutions (drugs and diagnostics) based on a thorough understanding of the gut microbiome, announces that it has entered into a collaborative development agreement with AbbVie.

12 Nov 2014

Tdap vaccination during pregnancy not associated with increased risk of preterm delivery

Among approximately 26,000 women, receipt of the tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis (Tdap) vaccine during pregnancy was not associated with increased risk of preterm delivery or small-for-gestational-age birth or with hypertensive disorders of pregnancy, although a small increased risk of being diagnosed with chorioamnionitis (an inflammation of the membranes that surround the fetus) was observed, according to a study in the November 12 issue of JAMA.

12 Nov 2014

Mayo Clinic study finds that chromosomal rearrangements can help trace lineage of lung cancer

A diagnostic test based on chromosomal rearrangements can trace the lineage of lung cancer to determine whether two separate lung cancers in the same patient are independent tumors or a tumor that has spread to another region of the lung, a Mayo Clinic study has found. For patients with multiple tumors, that distinction could mean the difference between early stage cancer that may be cured by surgery and incurable late-stage disease.

12 Nov 2014

Study examines overall survival of patients with chronic HCV infection, cirrhosis

Patients with chronic hepatitis C virus infection and advanced fibrosis or cirrhosis who attained sustained virological response (SVR) had survival comparable with that of the general population, whereas patients who did not attain SVR had reduced survival, according to a study in the November 12 issue of JAMA.

12 Nov 2014

Study: Heart attack, stroke survivors' physical limitations rapidly increase over decade

A record number of people are surviving heart attacks and stroke but those who do may experience a sharp decline in physical abilities that steadily accelerates over time, according to a new nationally-representative study led by the University of Michigan.

12 Nov 2014

Researchers identify key protein that can reduce severity of disease equivalent to MS in mice

In multiple sclerosis, the immune system goes rogue, improperly attacking the body's own central nervous system. Mobility problems and cognitive impairments may arise as the nerve cells become damaged.

12 Nov 2014

Researchers create microtube platform to analyze neuron growth

Tiny, thin microtubes could provide a scaffold for neuron cultures to grow so that researchers can study neural networks, their growth and repair, yielding insights into treatment for degenerative neurological conditions or restoring nerve connections after injury.

12 Nov 2014

Study reveals significant reduction in smoking following olfactory conditioning during sleep

New Weizmann Institute research may bring the idea of sleep learning one step closer to reality. The research, which appeared today in The Journal of Neuroscience, suggests that certain kinds of conditioning applied during sleep could induce us to change our behavior. The researchers exposed smokers to pairs of smells - cigarettes together with that of rotten eggs or fish - as the subjects slept, and then asked them to record how many cigarettes they smoked in the following week.

12 Nov 2014

Funding makes next-generation scientific equipment available to CBC research community

The Chicago Biomedical Consortium is announcing a $3 million Infrastructure Initiative to promote investment in high-impact, next-generation scientific equipment at its member universities. The Initiative aims to make modern and powerful tools available to the CBC research community at a time when federal grants for scientific infrastructure are scarce.

12 Nov 2014

UM researchers develop novel, family-focused, culturally-informed treatment for schizophrenia

Researchers at the University of Miami have developed a family-focused, culturally-informed treatment for schizophrenia (CIT-S). The program is one of the first to incorporate elements of the patient's cultural background as part of therapy.

11 Nov 2014

Research finding could lead to new therapies for preventing growth of plexiform neurofibromas

UT Southwestern Medical Center researchers have determined the specific type of cell that gives rise to large, disfiguring tumors called plexiform neurofibromas, a finding that could lead to new therapies for preventing growth of these tumors.

11 Nov 2014

Salivary mucins protect teeth from cariogenic bacterium

Salivary mucins, key components of mucus, actively protect the teeth from the cariogenic bacterium, Streptococcus mutans, according to research published ahead of print in Applied and Environmental Microbiology. The research suggests that bolstering native defenses might be a better way to fight dental caries than relying on exogenous materials, such as sealants and fluoride treatment, says first author Erica Shapiro Frenkel, of Harvard University, Cambridge, MA.

11 Nov 2014

Research reveals that majority of people unable to correctly identify obesity

The majority of people - including healthcare professionals - are unable to visually identify whether a person is a healthy weight, overweight or obese according to research by psychologists at the University of Liverpool.

11 Nov 2014

Experts review advances in understanding, treatment of bipolar disorder

Several lines of research have opened exciting new frontiers in scientific understanding and clinical management of bipolar disorder. Recent advances in bipolar disease research are described in this month's special issue of Harvard Review of Psychiatry.

11 Nov 2014

New findings could help develop therapeutic options for glycogen storage disease

Glycogen storage disorders, which affect the body's ability to process sugar and store energy, are rare metabolic conditions that frequently manifest in the first years of life. Often accompanied by liver and muscle disease, this inability to process and store glucose can have many different causes, and can be difficult to diagnose.

11 Nov 2014

Medical Research News

Effecting changes to FosB gene could help control addiction, depression

Pretreatment ILD is a risk factor for developing radiation pneumonitis in stage I NSCLC patients

Research opens new potential target against enterics

Scientists identify new therapeutic targets, screening test to uncover compounds for memory disorders

RPCI researchers identify two novel candidate prognostic markers for ovarian cancer

Enterome, AbbVie to develop novel diagnostic products, therapies for microbiome-related diseases

Tdap vaccination during pregnancy not associated with increased risk of preterm delivery

Mayo Clinic study finds that chromosomal rearrangements can help trace lineage of lung cancer

Study examines overall survival of patients with chronic HCV infection, cirrhosis

Study: Heart attack, stroke survivors' physical limitations rapidly increase over decade

Researchers identify key protein that can reduce severity of disease equivalent to MS in mice

Researchers create microtube platform to analyze neuron growth

Study reveals significant reduction in smoking following olfactory conditioning during sleep

Funding makes next-generation scientific equipment available to CBC research community

UM researchers develop novel, family-focused, culturally-informed treatment for schizophrenia

Research finding could lead to new therapies for preventing growth of plexiform neurofibromas

Salivary mucins protect teeth from cariogenic bacterium

Research reveals that majority of people unable to correctly identify obesity

Experts review advances in understanding, treatment of bipolar disorder

New findings could help develop therapeutic options for glycogen storage disease

Deciphering the Microbiome with The Microsetta Initiative

Leveraging the power of automation to boost research

Automating research - solutions and best practices

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