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New set of molecules could carry medicines into cells

Just as a scientist dressed in a lab coat and goggles might get stuck behind the velvet rope at a trendy bar, many otherwise good drugs can't get inside cells if they don't look the part. In a report published this week in ACS Central Science, researchers report a new set of molecules that could ferry medicines into cells by taking on the right charge and shape, easily sliding past lipid membranes.

16 Apr 2015

OSU study finds that injury prevention programs are not being used in high schools

Injury prevention programs can help reduce ankle, knee and other lower extremity injuries in sports, but the programs are not being widely used in high schools, a new study from Oregon State University has found.

16 Apr 2015

SGK1 enzyme protects brain cells in animal models of Parkinson's disease

Scientists from the Florida campus of The Scripps Research Institute have found how a widely known but little-studied enzyme protects brain cells in models of Parkinson's disease.

16 Apr 2015

Scientists identify way to potentially predict progression in patients with early form of breast cancer

Scientists in Manchester have identified a way to potentially predict which patients with an early form of breast cancer will experience disease progression.

16 Apr 2015

New metabolic blood profile method could help predict breast cancer

According to the World Health Organization, breast cancer is the most common cancer in women both in the developed and less developed world, and in the long term the scientists hope that the new method will lead to better prevention and early treatment of the disease.

16 Apr 2015

NIST researchers develop new 2D NMR fingerprinting method to measure monoclonal antibodies

National Institute of Standards and Technology researchers at the Institute for Bioscience and Biotechnology Research have demonstrated the most precise method yet to measure the structural configuration of monoclonal antibodies (mAbs), an important factor in determining the safety and efficacy of these biomolecules as medicines.

16 Apr 2015

Oxycodone-related deaths drop 25% after implementation of Prescription Drug Monitoring Program

Oxycodone-related deaths dropped 25 percent after Florida implemented its Prescription Drug Monitoring Program in late 2011 as part of its response to the state's prescription drug abuse epidemic, according to a team of UF Health researchers. The drop in fatalities could stem from the number of health care providers who used the program's database to monitor controlled substance prescriptions.

16 Apr 2015

Study: Sleep disturbances can hamper memory processes in children

Sleep disordered breathing can hamper memory processes in children, according to a new study. The research, which will be presented today at the Sleep and Breathing Conference (16 April 2015), found that disrupted sleep had an impact on different memory processes and how children learn.

15 Apr 2015

New Forsyth Institute study sheds light on connection between the mouth and heart

A new study from the Forsyth Institute is helping to shed more light on the important connection between the mouth and heart. According to research recently published online by the American Heart Association, scientists at Forsyth and Boston University have demonstrated that using an oral topical remedy to reduce inflammation associated with periodontitis, more commonly known as gum disease, also results in the prevention of vascular inflammation and can lower the risk of heart attack.

15 Apr 2015

Changes in JAK/STAT3 cell signaling pathway drive ALK-negative ALCL

The first-ever systematic study of the genomes of patients with ALK-negative anaplastic large cell lymphoma (ALCL), a particularly aggressive form of non-Hodgkin's lymphoma, shows that many cases of the disease are driven by alterations in the JAK/STAT3 cell signaling pathway.

15 Apr 2015

Ancient natural compound can protect the heart from hypertrophy

A natural compound derived from the bark of the magnolia tree, can protect the heart from hypertrophy, a thickening of cardiac muscle often caused by chronic high blood pressure that can lead to heart failure, researchers report in the April 14 issue of the online journal Nature Communications.

15 Apr 2015

Scientists find link between higher muscle mass and healthier bone development in children

Scientists at the University of Southampton have shown that higher muscle mass is strongly linked with healthier bone development in children.

15 Apr 2015

Optibrium to integrate ChemAxon's Plexus with StarDrop software platform

Optibrium and ChemAxon, developers of software and cheminformatics solutions for drug discovery, today announced the results of a collaboration to integrate ChemAxon's Plexus with Optibrium's StarDrop software suite. The integration of these platforms further enables researchers to develop strategies for efficient, high quality compound library design.

15 Apr 2015

WHO issues public statement calling for transparency in medical research

WHO today issued a public statement calling for the disclosure of results from clinical trials for medical products, whatever the result.The move aims to ensure that decisions related to the safety and efficacy of vaccines, drugs and medical devices for use by populations are supported by the best available evidence.

15 Apr 2015

New Clinical Conductor CTMS functionality helps healthcare organizations better manage clinical research

The team behind Clinical Conductor CTMS recently debuted new functionality that allows healthcare organizations to better manage adaptive and dynamic clinical research that is becoming more relevant in the industry every year. Included in this quarter’s release is functionality that lets users create snapshots of past budgets to be used for better negotiations and invoicing, the ability for organizations to create multiple charge masters, and functionality that provides better handling of protocol amendments.

15 Apr 2015

Study: Children with type 1 diabetes five times more likely to be admitted to hospital

Children living with type 1 diabetes are nearly five times more likely to be admitted to hospital than non-diabetic children, a new study (attached) has found.

15 Apr 2015

Johns Hopkins researchers create the largest library of brain cells from ALS patients

Researchers at Johns Hopkins Medicine have transformed skin cells from patients with Lou Gehrig’s disease, or amyotrophic lateral sclerosis (ALS), into brain cells affected by the progressive, fatal disease and deposited those human-made cells into the first public ALS cell library, enabling scientists to better study the disease.

15 Apr 2015

Experts to make roadmap for future research, clinical trials for SCLC patients at IASLC workshop

Small cell lung cancer (SCLC) will be the concentrated focus when 100 global experts in the field meet for a workshop hosted by the International Association for the Study of Lung Cancer on April 22-24, 2015 at Memorial Sloan Kettering Cancer Center in New York City.

15 Apr 2015

New research could transform treatments for patients with Barrett's Oesophagus

New research from the University of Warwick and University Hospitals Coventry and Warwickshire NHS Trust could transform treatments and diagnosis for a common digestive condition which affects thousands of patients.

15 Apr 2015

Genetically modified Salmonella can help kill cancer cells

A new study has demonstrated that genetically modified Salmonella can be used to kill cancer cells. The study is published in this week's issue of mBio, an American Society for Microbiology online-only, open access journal.

15 Apr 2015

Medical Research News

New set of molecules could carry medicines into cells

OSU study finds that injury prevention programs are not being used in high schools

SGK1 enzyme protects brain cells in animal models of Parkinson's disease

Scientists identify way to potentially predict progression in patients with early form of breast cancer

New metabolic blood profile method could help predict breast cancer

NIST researchers develop new 2D NMR fingerprinting method to measure monoclonal antibodies

Oxycodone-related deaths drop 25% after implementation of Prescription Drug Monitoring Program

Study: Sleep disturbances can hamper memory processes in children

New Forsyth Institute study sheds light on connection between the mouth and heart

Changes in JAK/STAT3 cell signaling pathway drive ALK-negative ALCL

Ancient natural compound can protect the heart from hypertrophy

Scientists find link between higher muscle mass and healthier bone development in children

Optibrium to integrate ChemAxon's Plexus with StarDrop software platform

WHO issues public statement calling for transparency in medical research

New Clinical Conductor CTMS functionality helps healthcare organizations better manage clinical research

Study: Children with type 1 diabetes five times more likely to be admitted to hospital

Johns Hopkins researchers create the largest library of brain cells from ALS patients

Experts to make roadmap for future research, clinical trials for SCLC patients at IASLC workshop

New research could transform treatments for patients with Barrett's Oesophagus

Genetically modified Salmonella can help kill cancer cells

The evolution of OCT for retinal imaging and disease intervention

Supercharging Next-Gen Antibody Discovery with AI and High-Throughput Experimentation

Prof. Dr. Kristina Kusche-Vihrog

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