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BIDMC receives $20 million grant to evaluate, test monoclonal antibodies for HIV treatment

Beth Israel Deaconess Medical Center has received a four-year, $20 million grant from the Bill & Melinda Gates Foundation to evaluate and test broadly neutralizing monoclonal antibodies for the treatment of HIV.

3 Oct 2014

Depression contributes to abnormal pain processes in IBS patients

High rates of anxiety and depression amongst patients with irritable bowel syndrome (IBS) have led many researchers to believe there could be a causal relationship between psychological factors and IBS symptoms. Now, scientists in Germany have found clear evidence that patients with IBS process pain signals from the gut abnormally, and that disturbed brain responses to pain are particularly pronounced in patients with more depression symptoms.

3 Oct 2014

Parent coaching intervention benefits preschool-aged children with autism

A parent coaching intervention brings meaningful benefits for preschool-aged children with autism-spectrum disorders (ASD), according to a clinical trial in the October Journal of Developmental & Behavioral Pediatrics, the official journal of the Society for Developmental and Behavioral Pediatrics.

3 Oct 2014

Schizophrenia and bipolar disorder share common pathophysiological features

Schizophrenia and bipolar disorder both appear to be associated with dendritic spine loss in the brain, suggesting the two distinct disorders may share common pathophysiological features, write author Glenn T. Konopaske, M.D., and colleagues at McLean Hospital, Belmont, Mass., and Harvard Medical School, Boston.

3 Oct 2014

MD Anderson's James P. Allison to receive 2014 Louisa Gross Horwitz Prize for work on immunotherapy

Columbia University will award the 2014 Louisa Gross Horwitz Prize to James P. Allison, PhD, of the University of Texas MD Anderson Cancer Center, for his work on understanding the process of T-cell activation and for developing therapies that harness the immune system to fight cancer.

3 Oct 2014

Researchers receive $4 million NIH grant to bioengineer miniature pancreas in a dish

Although type 1 diabetes can be controlled with insulin injections and lifestyle modifications, major advances in treating the disease have not been made in more than two decades and there remain fundamental gaps in what is understood about its causes and how to halt its progression.

3 Oct 2014

Taking NSAIDs with other drugs can increase risk of upper GI bleeding, study finds

Nonsteroidal anti-inflammatory drugs (NSAIDs) - such as ibuprofen and aspirin - increase one's risk of upper gastrointestinal bleeding. When taken in combination with other drugs, this risk is significantly higher, according to new research appearing in the October issue of Gastroenterology, the official journal of the American Gastroenterological Association.

3 Oct 2014

Grand Valley researcher receives grant to study molecular biomarkers to monitor Parkinson's disease

A researcher at Grand Valley State University has received a grant to continue studying if molecular biomarkers can be used to monitor the advancement of Parkinson's disease.

3 Oct 2014

Researchers identify biomarker that can predict GS7 prostate cancer patients

Researchers at The University of Texas MD Anderson Cancer Center have identified a biomarker living next door to the KLK3 gene that can predict which GS7 prostate cancer patients will have a more aggressive form of cancer.

3 Oct 2014

Study uncovers new pathway for treating high blood pressure, heart failure

New research by scientists at the University of Maryland School of Medicine and the Ottawa Heart Institute has uncovered a new pathway by which the brain uses an unusual steroid to control blood pressure.

3 Oct 2014

Brain structure changes differ between schizophrenia symptoms

The specific areas of the brain with reduced grey matter in patients with schizophrenia differ according to whether they have predominant positive, negative or disorganised symptoms, research suggests.

2 Oct 2014

Dendritic spine density also reduced in bipolar disorder

Patients with bipolar disorder have significant dendritic spine loss in the dorsolateral prefrontal cortex, postmortem findings show.

2 Oct 2014

Clinical practice study supports ISBD recommendations

Findings in patients with bipolar disorder given short-term antidepressant treatment support the recent International Society for Bipolar Disorder’s task force recommendations.

2 Oct 2014

Weekly growth hormone on course for phase III in children

A long-lasting formulation of human growth hormone appears to be as effective as standard daily treatment in paediatric patients with growth hormone deficiency, researchers reported at the European Society of Paediatric Endocrinology annual meeting in Dublin, Ireland.

2 Oct 2014