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Mucosal lymphoid cells key to S. pneumoniae defence

Type 3 innate lymphoid cells in the lung mucosa are activated early in the course of infection with Streptococcus pneumoniae and are a major source of interleukin-22 production, research reveals.

11 Aug 2014

First-line sunitinib superior to everolimus for metastatic RCC

Results for the RECORD-3 trial support the current strategy of first-line sunitinib followed by second-line everolimus for the treatment of patients with metastatic renal cell carcinoma.

11 Aug 2014

Midlife hypertension link to later-life cognitive decline strengthened

Analysis of the Atherosclerosis Risk in Communities study cohort supports an association between elevated blood pressure in midlife and increased cognitive decline in older age.

11 Aug 2014

Baseline characteristics influence Parkinson’s disease course

Motor progression in Parkinson’s disease is non-linear and occurs in three distinct phases, all of which are affected by baseline variables such as gender, age at diagnosis, disease subtype, cognitive status and motor score, study findings indicate.

11 Aug 2014

Researchers discover how immunosensory system attacks viruses on a molecular level

Our immunosensory system detects virus such as influenza via specific characteristics of viral ribonucleic acid. Previously, it was unclear how the immune system prevents viruses from simply donning molecular camouflage in order to escape detection.

11 Aug 2014

CRI researchers identify gene linked to several childhood cancers

Researchers at the Children-s Medical Center Research Institute at UT Southwestern have identified a gene that contributes to the development of several childhood cancers, in a study conducted with mice designed to model the cancers.

11 Aug 2014

GW researcher awarded grant to develop a model system to study PN infection

According to a recent World Health Organization report of the leading causes of death worldwide, one-third of all deaths are due to infectious and parasitic diseases. There are currently no vaccines for parasitic nematode (PN), or worm infections in humans, and development of new drugs and vaccines will stall until researchers have a better understanding of PN biology.

11 Aug 2014

Antimalarial agent chloroquine normalizes abnormal tumor blood vessels

A recent study by investigators at VIB and KU Leuven has demonstrated that chloroquine also normalizes the abnormal blood vessels in tumors. This blood vessel normalization results in an increased barrier function on the one hand -- thereby blocking cancer cell dissemination and metastasis -- and in enhanced tumor perfusion on the other hand, which increases the response of the tumor to chemotherapy.

11 Aug 2014

ALS Association awards 21 new research grants to find cure for amyotrophic lateral sclerosis

The ALS Association announced today that it has awarded 21 new research grants totaling nearly $3.5 million to find treatments and a cure for amyotrophic lateral sclerosis (ALS). The grants were awarded to scientists from laboratories located in nine different states in the United States as well as from the United Kingdom, France, Canada, Switzerland, Israel and Australia.

11 Aug 2014

New method could make cashews safer for people with allergies

For the millions of adults and children in the U.S. who have to shun nuts to avoid an allergic reaction, help could be on the way. Scientists are now developing a method to process cashews - and potentially other nuts - that could make them safer to eat for people who are allergic to them.

11 Aug 2014

Scientists identify mechanism by which inherited neurological disease causes muscle weakness in men

Researchers at University of California, San Diego School of Medicine have identified the mechanism by which a rare, inherited neurodegenerative disease causes often crippling muscle weakness in men, in addition to reduced fertility.

11 Aug 2014

US lung cancer rates uncover trends related to cancer subtype, sex, race/ethnicity and age

A new analysis confirms that US lung cancer rates are declining overall, but it also uncovers previously unrecognized trends related to cancer subtype, sex, race/ethnicity, and age.

11 Aug 2014

Patient with mechanical heart pump receives new gene therapy for heart failure

For the first time in the world, a patient with a mechanical heart pump has received a new gene therapy for heart failure at Harefield Hospital, London.

11 Aug 2014

Demand of materials used to produce smartphones need to be addressed, say researchers

Many of today's technological innovations from the iPhone to electric motors for hybrid cars require the use of materials - elements - that are scarce or difficult to obtain. As demand for these devices grows, the problem of dwindling critical element supplies must be addressed.

11 Aug 2014

Black and Hispanic SLE patients are more likely to be readmitted than white patients

A new study reveals that one in six patients with systemic lupus erythematosus (SLE) is readmitted to the hospital within 30 days of being discharged.

11 Aug 2014

European Commission approves EYLEA Injection for treatment of visual impairment due to DME

Regeneron Pharmaceuticals, Inc. today announced that EYLEA® (aflibercept) Injection has been approved by the European Commission for the treatment of visual impairment due to Diabetic Macular Edema.

11 Aug 2014

Regular physical activity decreases risk for invasive breast cancer among postmenopausal women

Postmenopausal women who in the past four years had undertaken regular physical activity equivalent to at least four hours of walking per week had a lower risk for invasive breast cancer compared with women who exercised less during those four years, according to data published in Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association for Cancer Research.

11 Aug 2014

Breech births increase fetal mortality rate compared to elective vaginal delivery

While a rise in cesarean section (C-section) delivery rates due to breech presentation has improved neonatal outcome, 40% of term breech deliveries in the Netherlands are planned vaginal deliveries.

11 Aug 2014

Frequent marijuana use can have negative effect on brains of teenagers

Frequent marijuana use can have a significant negative effect on the brains of teenagers and young adults, including cognitive decline, poor attention and memory, and decreased IQ, according to psychologists discussing public health implications of marijuana legalization at the American Psychological Association's 122nd Annual Convention.

11 Aug 2014

Nearly 40% of women who earn engineering degrees quit profession or never enter the field

Nearly 40 percent of women who earn engineering degrees quit the profession or never enter the field, and for those who leave, poor workplace climates and mistreatment by managers and co-workers are common reasons, according to research presented at the American Psychological Association's 122nd Annual Convention.

11 Aug 2014

Medical Research News

Mucosal lymphoid cells key to S. pneumoniae defence

First-line sunitinib superior to everolimus for metastatic RCC

Midlife hypertension link to later-life cognitive decline strengthened

Baseline characteristics influence Parkinson’s disease course

Researchers discover how immunosensory system attacks viruses on a molecular level

CRI researchers identify gene linked to several childhood cancers

GW researcher awarded grant to develop a model system to study PN infection

Antimalarial agent chloroquine normalizes abnormal tumor blood vessels

ALS Association awards 21 new research grants to find cure for amyotrophic lateral sclerosis

New method could make cashews safer for people with allergies

Scientists identify mechanism by which inherited neurological disease causes muscle weakness in men

US lung cancer rates uncover trends related to cancer subtype, sex, race/ethnicity and age

Patient with mechanical heart pump receives new gene therapy for heart failure

Demand of materials used to produce smartphones need to be addressed, say researchers

Black and Hispanic SLE patients are more likely to be readmitted than white patients

European Commission approves EYLEA Injection for treatment of visual impairment due to DME

Regular physical activity decreases risk for invasive breast cancer among postmenopausal women

Breech births increase fetal mortality rate compared to elective vaginal delivery

Frequent marijuana use can have negative effect on brains of teenagers

Nearly 40% of women who earn engineering degrees quit profession or never enter the field

Precision in every drop: Inside Hamilton’s syringe technology

Exploring the Future of Neuroscience Drug Discovery

Genomic conservation in Thailand's mangroves

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