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Molecular signaling pathways in the gut influence NAFLD

Nonalcoholic fatty liver disease (NAFLD) is the most common liver disorder and affects approximately 1 billion people worldwide. It is not clear how this disease develops, but recent studies suggest that the bacterial population in the gut influences NAFLD.

15 Dec 2014

Heroin use impacts HIV disease progression

Researchers at Yale and Boston University and their Russian collaborators have found that occasional heroin use by HIV-positive patients may be particularly harmful to the immune system and worsens HIV disease, compared to persistent or no heroin use.

15 Dec 2014

Tendyne Feasibility Study: Tendyne successfully implants TMVI system in first patient

Tendyne Holdings, Inc., a privately held clinical stage medical device company, announced today that in November 2014 the Tendyne Transcatheter Mitral Valve Implantation system (TMVI) was successfully implanted in the first patient of the Tendyne Feasibility Study. This was the first patient enrolled in a three continent, multicenter trial, which aims to generate insight into the safety and performance of the Tendyne device in inoperable patients suffering from mitral regurgitation.

15 Dec 2014

Higher levels of selenium linked to decreased risk of colorectal cancer

Higher levels of selenium are associated with a decreased risk of colorectal cancer, according to new research published in the International Journal of Cancer (December).

15 Dec 2014

Postoperative recurrent disease affects NSCLC survival after gefitinib

Patients with postoperative recurrent non-small-cell lung cancer harbouring epidermal growth factor receptor mutations have longer progression-free and overall survival with gefitinib treatment, than those with stage IV disease, Japanese researchers report.

15 Dec 2014

Umbilical cord clamping influences resistance to oxidative stress in newborns

A study conducted by University of Granada scientists (from the Physiology, Obstetrics and Gynaecology Departments) and from the San Cecilio Clinical Hospital (Granada) has demonstrated that delaying the cutting of the umbilical cord in newborns by two minutes leads to a better development of the baby during the first days of life.

15 Dec 2014

Children who skip meals more likely to have excess body fat, increased cardiometabolic risk

Children who skip main meals are more likely to have excess body fat and an increased cardiometabolic risk already at the age of 6 to 8 years, according to a Finnish study. A higher consumption of sugary drinks, red meat and low-fat margarine and a lower consumption of vegetable oil are also related to a higher cardiometabolic risk.

15 Dec 2014

UT Southwestern researchers identify possible therapy to treat neurofibromatosis type 1

UT Southwestern Medical Center researchers have identified a possible therapy to treat neurofibromatosis type 1 or NF1, a childhood neurological disease characterized by learning deficits and autism that is caused by inherited mutations in the gene encoding a protein called neurofibromin.

15 Dec 2014

Photoacoustic imaging has potential to be used as noninvasive method to detect cervical cancer

Cervical cancer is, in many ways, a shining example of how successful the war on cancer can be. Thanks largely to the advent of Pap smear screening, U.S. cervical cancer deaths decreased dramatically, by more than 60 percent, between 1955 and 1992. In the last two decades, better treatment outcomes and more powerful imaging techniques have steadily pushed 5-year survival rates ever higher.

15 Dec 2014

Added benefit of aflibercept not proven in patients with diabetic macular oedema

Since August 2014, aflibercept (trade name Eylea) has been available also for patients with visual impairment due to diabetic macular oedema (DMO). The German Institute for Quality and Efficiency in Health Care examined in a dossier assessment whether this drug offers an added benefit over the appropriate comparator therapy.

15 Dec 2014

ADIPOQ gene variations linked to colorectal cancer risk, new study reveals

Adiponectin, a collagen-like protein secreted by fat cells, derives from the ADIPOQ gene. Variations in this gene may increase risk for type 2 diabetes, cardiovascular disease, and various cancers. A new study that links specific variations in the ADIPOQ gene to either higher or lower colorectal cancer risk is published in Genetic Testing and Molecular Biomarkers, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers.

15 Dec 2014

EMAHSN seeks innovative projects focusing on cancer diagnosis and treatment

A ‘call to action’ has been issued to seek innovative solutions to one of the East Midlands’ biggest healthcare challenges - cancer - which every year affects 23,000 people across the region.

14 Dec 2014

Maf1 protein that makes other proteins also controls fat levels in the body

Like a smart sensor that adjusts the lighting in each room and a home's overall temperature, a protein that governs the making of other proteins in the cell also appears capable of controlling fat levels in the body.

14 Dec 2014

New study compares usefulness of two biomarkers released into the blood after TBI

In cases of traumatic brain injury (TBI), predicting the likelihood of a cranial lesion and determining the need for head computed tomography (CT) can be aided by measuring markers of bone injury in the blood.

14 Dec 2014

Environmental factors influence how genetic variants affect the brain, behaviour

Both positive and negative experiences influence how genetic variants affect the brain and thereby behaviour, according to a new study. "Evidence is accumulating to show that the effects of variants of many genes that are common in the population depend on environmental factors.

14 Dec 2014

ETH Zurich, University of Zurich jointly open new translational research centre

ETH Zurich and the University of Zurich are taking their long-standing partnership to a new level with a new translational research centre. The two universities are founding the Wyss Translational Center Zurich (WTZ) with funds donated by Hansjörg Wyss to the ETH Zurich Foundation.

14 Dec 2014

NTU scientists discover how malaria parasite develops resistance towards front-line drugs

Scientists from Nanyang Technological University have discovered exactly how the malaria parasite is developing resistance towards the most important front-line drugs used to treat the disease.

14 Dec 2014

New study eliminates hepatitis C virus as causative factor of mental impairment in HIV patients

Advances in treatment for human immunodeficiency virus (HIV) have made it possible for people with HIV to survive much longer. As they age, however, many experience impaired thinking, memory loss, mood swings and other evidence of impaired mental function.

14 Dec 2014

Experts expose fundamental role of chaos and complexity in biological information processing

The interdisciplinary approach to problems that till recently were addressed in the hermetic framework of distinct disciplines such as physics, informatics, biology or sociology constitutes today one of the most active and innovative areas of science, where fundamental issues meet problems of everyday concern.

14 Dec 2014

Researchers uncover mechanism that helps white fat cells to become browner

White adipose tissue stores excess calories as fat that can be released for use in other organs during fasting. Mammals also have small amounts of brown adipose tissue, which primarily acts as an effective fat burner for the production of heat. Now researchers from the University of Southern Denmark have uncovered the mechanism by which white fat cells from humans gets reprogrammed to become browner.

14 Dec 2014

Medical Research News

Molecular signaling pathways in the gut influence NAFLD

Heroin use impacts HIV disease progression

Tendyne Feasibility Study: Tendyne successfully implants TMVI system in first patient

Higher levels of selenium linked to decreased risk of colorectal cancer

Postoperative recurrent disease affects NSCLC survival after gefitinib

Umbilical cord clamping influences resistance to oxidative stress in newborns

Children who skip meals more likely to have excess body fat, increased cardiometabolic risk

UT Southwestern researchers identify possible therapy to treat neurofibromatosis type 1

Photoacoustic imaging has potential to be used as noninvasive method to detect cervical cancer

Added benefit of aflibercept not proven in patients with diabetic macular oedema

ADIPOQ gene variations linked to colorectal cancer risk, new study reveals

EMAHSN seeks innovative projects focusing on cancer diagnosis and treatment

Maf1 protein that makes other proteins also controls fat levels in the body

New study compares usefulness of two biomarkers released into the blood after TBI

Environmental factors influence how genetic variants affect the brain, behaviour

ETH Zurich, University of Zurich jointly open new translational research centre

NTU scientists discover how malaria parasite develops resistance towards front-line drugs

New study eliminates hepatitis C virus as causative factor of mental impairment in HIV patients

Experts expose fundamental role of chaos and complexity in biological information processing

Researchers uncover mechanism that helps white fat cells to become browner

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