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Toxicity profiles for everolimus, temsirolimus differ in advanced RCC

Non-infectious pneumonitis and stomatitis occur more frequently in patients with advanced renal cell carcinoma treated with everolimus than temsirolimus, whereas temsirolimus is associated with a higher incidence of fatigue, rash and asthenia, a retrospective study reports.

13 Nov 2014

Cytoreductive nephrectomy benefits limited by preoperative risk factors

The survival benefit of cytoreductive nephrectomy when used in conjunction with targeted therapy for metastatic renal cell carcinoma depends on the number of preoperative risk factors a patient carries, study findings indicate.

13 Nov 2014

Bipolar mixed episodes increase significantly under DSM-5

Using the most recent diagnostic criteria increases the prevalence of mixed features in patients with bipolar disorder more than threefold, study findings indicate.

13 Nov 2014

Suicidal ideation link to suicide strong in schizophrenia spectrum disorders

The association between suicidal ideation and later suicide is much stronger in patients with schizophrenia spectrum psychosis than in those with mood disorders, show results of a systematic meta-analysis.

13 Nov 2014

Bevacizumab–erlotinib combined efficacy may depend on VEGF level

Bevacizumab may enhance the antitumour activity of erlotinib by increasing the intratumoural concentration of erlotinib in some non-small-cell lung cancers expressing high levels of vascular endothelial growth factor, Japanese researchers report.

13 Nov 2014

Denmark researchers calculate the real burden of foodborne infections

Campylobacter is the foodborne bacteria that contributes most to the burden of disease in Denmark. This is the finding of a study from the National Food Institute, Technical University of Denmark, which for the first time in Denmark ranks three foodborne bacteria according to the burden of disease they impose on society as a whole.

13 Nov 2014

Study reveals the origin of world's AIDS pandemic

A study published in Science magazine reveals for the first time where, when and how the world's AIDS pandemic originated. Thanks to a statistical analysis of all the genetic data available on the human immunodeficiency virus (HIV), an international research team has just confirmed that the scourge broke out in 1920 in Kinshasa, the capital of what is now the Democratic Republic of the Congo.

13 Nov 2014

Vitamin B12, folic acid supplements may not reduce risk of memory and thinking problems

Taking vitamin B12 and folic acid supplements may not reduce the risk of memory and thinking problems after all, according to a new study published in the November 12, 2014, online issue of Neurology, the medical journal of the American Academy of Neurology. The study is one of the largest to date to test long-term use of supplements and thinking and memory skills.

13 Nov 2014

Study offers unprecedented picture of how children frequently suffer head injuries

A study in which more than 43,000 children were evaluated for head trauma offers an unprecedented picture of how children most frequently suffer head injuries, report physicians at Washington University School of Medicine in St. Louis and the University of California, Davis, School of Medicine.

13 Nov 2014

New NIH-funded study aims to find novel way to treat iron deficiency anemia in children

Penn State College of Medicine and University of Wisconsin have been awarded a five-year, $2.5 million grant from the National Institutes of Health to fund the study of a novel way to treat iron deficiency anemia in children. Iron deficiency is the most common nutritional deficiency and the leading cause of anemia in the United States.

13 Nov 2014

Searching online for diagnosis before visiting doctor can predict dengue fever outbreaks in China

Queensland University of Technology researchers have found the habit of Googling for an online diagnosis before visiting the doctor can be a powerful predictor of infectious diseases outbreaks.

13 Nov 2014

Unique immunochemotherapy approach to treating pancreatic cancer

VCU Massey Cancer Center and VCU Institute of Molecular Medicine researchers discovered a unique approach to treating pancreatic cancer that may be potentially safe and effective. The treatment method involves immunochemotherapy - a combination of chemotherapy and immunotherapy, which uses the patient's own immune system to help fight against disease.

13 Nov 2014

Scientists discover ways to detect several toxic flame retardants in people's bodies

A new peer-reviewed study found that people are contaminated with several toxic flame retardants rarely studied in the US, including one that has never before been detected in Americans called TCEP. Scientists tested urine samples of California residents for biomarkers of six chemicals, all of which were present.

13 Nov 2014

Researchers explore new ways to treat, prevent Streptococcus pneumoniae

Scientists from Massachusetts Eye and Ear/Harvard Medical School Department of Ophthalmology have used the power of new genomic technology to discover that microbes that commonly infect the eye have special, previously unknown properties. These properties are predicted to allow the bacterium -- Streptococcus pneumoniae -- to specifically stick to the surface of the eye, grow, and cause damage and inflammation.

13 Nov 2014

McGill study helps identify people at risk for oral human papillomavirus

Oral human papillomavirus (HPV) infections were more common among men who had female partners with oral and/or genital HPV infection, suggesting that the transmission of HPV occurs via oral-oral and oral-genital routes, according to a McGill University study published in Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association for Cancer Research.

13 Nov 2014

Researchers find that yellow fever mosquitoes contain odor-detecting gene

One of the world's deadliest mosquitoes sustains its taste for human blood thanks in part to a genetic tweak that makes it more sensitive to human odor, according to new research.

13 Nov 2014

Study identifies genetic alterations that contribute to growth and recurrence of Ewing sarcoma

An international collaboration has identified frequent mutations in two genes that often occur together in Ewing sarcoma (EWS) and that define a subtype of the cancer associated with reduced survival.

13 Nov 2014

Scientists receive NARSAD Distinguished Investigator Grants for mental health research

The Brain & Behavior Research Foundation today announced the award of NARSAD Distinguished Investigator Grants valued at $1.5 million to 15 scientists, who are full professors or the equivalent, conducting innovative projects in diverse areas of neurobiological and behavioral research.

13 Nov 2014

Walter and Eliza Hall Institute receives $2.5 million grant to support cancer research

Australian cancer researchers will gain access to first-in-Australia technology through new funding from Australian Cancer Research Foundation to the Walter and Eliza Hall Institute. The $2.5 million grant will allow the establishment of the ACRF Breakthrough Technologies Laboratory, providing new insights into how cancer develops, and how it can be more effectively treated. The laboratory is one of four initiatives announced by ACRF last night.

13 Nov 2014

Guidelines to limit tours of overseas duty reduce mental health problems in UK’s armed forces

Prolonged periods of deployment among the UK’s armed forces have fallen since the introduction of the “Harmony Guidelines” to limit tours of overseas duty—which might have led to a reduction in mental health problems, new research published in The Lancet Psychiatry journal suggests.

13 Nov 2014

Medical Research News

Toxicity profiles for everolimus, temsirolimus differ in advanced RCC

Cytoreductive nephrectomy benefits limited by preoperative risk factors

Bipolar mixed episodes increase significantly under DSM-5

Suicidal ideation link to suicide strong in schizophrenia spectrum disorders

Bevacizumab–erlotinib combined efficacy may depend on VEGF level

Denmark researchers calculate the real burden of foodborne infections

Study reveals the origin of world's AIDS pandemic

Vitamin B12, folic acid supplements may not reduce risk of memory and thinking problems

Study offers unprecedented picture of how children frequently suffer head injuries

New NIH-funded study aims to find novel way to treat iron deficiency anemia in children

Searching online for diagnosis before visiting doctor can predict dengue fever outbreaks in China

Unique immunochemotherapy approach to treating pancreatic cancer

Scientists discover ways to detect several toxic flame retardants in people's bodies

Researchers explore new ways to treat, prevent Streptococcus pneumoniae

McGill study helps identify people at risk for oral human papillomavirus

Researchers find that yellow fever mosquitoes contain odor-detecting gene

Study identifies genetic alterations that contribute to growth and recurrence of Ewing sarcoma

Scientists receive NARSAD Distinguished Investigator Grants for mental health research

Walter and Eliza Hall Institute receives $2.5 million grant to support cancer research

Guidelines to limit tours of overseas duty reduce mental health problems in UK’s armed forces

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