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New computational method reveals links between bacterial growth rates and type II diabetes, IBD

It is increasingly clear that the thousands of different bacteria living in our intestinal tract - our microbiome - have a major impact on our health. But the details of the microbiome's effects are still fairly murky.

3 Sep 2015

Valerion announces positive results from non-clinical pilot study of VAL-1221 for treatment of Pompe disease

Valerion Therapeutics, LLC yesterday announced positive results from a non-clinical "proof of concept" pilot study for a novel humanized antibody and acid alpha glucosidase (GAA) fusion candidate for the treatment of Pompe disease.

3 Sep 2015

Appropriate pre-surgical physical therapy can help joint replacement patients recover faster

For people contemplating a hip or knee replacement, the prospect of a long post-surgical recovery can be a daunting one. The grueling rehabilitation sessions, the frustration of re-learning everyday movements, the weeks of waiting to return to "normal"— it's almost enough to make patients reconsider surgery.

3 Sep 2015

Researchers examine use of MRI after birth to identify children at risk of later academic impairment

School age children who are born prematurely are more likely to have low mathematical achievement, thought to be associated with reduced working memory and number skills, according to a new study published today in the neurology journal Brain.

3 Sep 2015

Regulatory T cells may reduce susceptibility to allergies

Susceptibility to allergies reduced by increased production of regulatory T cells. This is the main finding of a current study being conducted at the Institute of Immunology at MedUni Vienna, headed up by Winfried F. Pickl. The initial results of this study by Alina Neunkirchner, which looks at the root cause of the development of allergies, are being presented at the European Congress of Immunology, which starts in Vienna this Sunday (6 - 9 September 2015, Austria Center Vienna).

3 Sep 2015

Guilting middle-schoolers into exercising may not increase activity, new study finds

Just like attempts at influencing hairstyles or clothing can backfire, adults who try to guilt middle-schoolers into exercising won't get them to be any more active, according to a new study by University of Georgia researchers.

3 Sep 2015

Central visual field loss may delay driver's ability to detect pedestrians in timely manner

Vision researchers in Boston have published the second paper of a study designed to determine if a driver who suffers from loss of central vision is able to detect pedestrians in a timely manner when driving.

3 Sep 2015

Finding better treatment for adolescent idiopathic scoliosis

In an effort to find a better treatment for spinal curvature in children and young people, the EU's "StimulAIS" project is focused on electrostimulation of muscles. Fraunhofer scientists worked with partners from industry and research to develop a prototype implant that would do the job.

3 Sep 2015

Depressive symptoms remain high in coastal areas affected by the Great East Japan Earthquake

A second round of aggregate findings from a study by Tohoku University's Tohoku Medical Megabank Organization (ToMMo) has revealed that depressive symptoms continue to be higher in coastal areas than in inland areas affected by the Great East Japan Earthquake and the tsunami that followed.

3 Sep 2015

Cells expressing faulty CFTR channel to TNF-α can 'fix' cystic fibrosis cells

Scientific experiments examining what happens to the faulty channel protein that causes cystic fibrosis during inflammation have yielded unexpected and exciting results. The study, conducted by Sara Bitam and her colleagues at INSERM in France, has just passed peer review on open science publishing platform F1000Research.

3 Sep 2015

Preserving natural structure of dietary fibre during food production can help lower blood sugar levels

A new study led by scientists at King's College London shows that preserving the natural structure of dietary fibre during food production can help to slow the rise in blood sugar levels after a meal.

3 Sep 2015

Scientists identify new mechanism for severe early infant epilepsy

Scientists at Karolinska Institutet and Karolinska University Hospital in Sweden have discovered a new explanation for severe early infant epilepsy. Mutations in the gene encoding the protein KCC2 can cause the disease, hereby confirming an earlier theory.

3 Sep 2015

Scientists map genes responsible for early embryonic development in humans

An international team of scientists led from Sweden's Karolinska Institutet has for the first time mapped all the genes that are activated in the first few days of a fertilized human egg. The study, which is being published in the journal Nature Communications, provides an in-depth understanding of early embryonic development in human - and scientists now hope that the results will help finding for example new therapies against infertility.

3 Sep 2015

Research findings may help explain why drug treatments for addiction, depression are not always effective

New research may help explain why drug treatments for addiction and depression don't work for some patients. The conditions are linked to reward and aversion responses in the brain. Working in mice, researchers at Washington University School of Medicine in St. Louis have discovered brain pathways linked to reward and aversion behaviors are in such close proximity that they unintentionally could be activated at the same time.

3 Sep 2015

Imetelstat drug shows promise in treating patients with myelofibrosis

Imetelstat, a novel drug that targets telomerase, has demonstrated potential value in treating patients with myelofibrosis, according to the results of a study published today in the New England Journal of Medicine.

3 Sep 2015

Diabetes may be linked to buildup of brain tangles associated with Alzheimer’s disease

Diabetes may be linked to the buildup of tangles or tau in the brain, separate from Alzheimer's disease, according to a new study published in the September 2, 2015, online version of Neurology, the medical journal of the American Academy of Neurology.

3 Sep 2015

Novel approach to reduce 'bad' lipids in blood circulation

Xian-Cheng Jiang, PhD, professor of cell biology at SUNY Downstate Medical Center, has led a study identifying a new approach for lowering "bad" lipids in blood circulation, a critical means to combat devastating cardiovascular diseases such as atherosclerosis. The research was published in the online edition of Gastroenterology.

3 Sep 2015

Study reveals new epigenetic mechanism underlying progression of cancer tumors

Aggressive cancer growth and alterations in gene activity without changes in DNA sequence (epigenetics) are associated with mutant p53 proteins, according to new research from the Perelman School of Medicine at the University of Pennsylvania.

3 Sep 2015

Reducing SSB intake among children and adolescents associated with greater increase in HDL-C

In the first study to investigate blood lipid levels in association with consumption of sugar-sweetened beverages (SSBs) in a racially and ethnically diverse sample of Boston area schoolchildren, researchers found there was an inverse association between SSB intake changes and HDL-cholesterol increases (HDL-C is the "good cholesterol").

3 Sep 2015

ISU researcher examines how supplements, resistance training improve muscle strength in older adults

The loss of muscle strength and function, what's known as sarcopenia, is a natural part of aging. It's also a growing public health concern because of the risk for falls, injury and decline in quality of life. That's why an Iowa State University researcher is working to slow or reverse the progression of sarcopenia.

3 Sep 2015

Medical Research News

New computational method reveals links between bacterial growth rates and type II diabetes, IBD

Valerion announces positive results from non-clinical pilot study of VAL-1221 for treatment of Pompe disease

Appropriate pre-surgical physical therapy can help joint replacement patients recover faster

Researchers examine use of MRI after birth to identify children at risk of later academic impairment

Regulatory T cells may reduce susceptibility to allergies

Guilting middle-schoolers into exercising may not increase activity, new study finds

Central visual field loss may delay driver's ability to detect pedestrians in timely manner

Finding better treatment for adolescent idiopathic scoliosis

Depressive symptoms remain high in coastal areas affected by the Great East Japan Earthquake

Cells expressing faulty CFTR channel to TNF-α can 'fix' cystic fibrosis cells

Preserving natural structure of dietary fibre during food production can help lower blood sugar levels

Scientists identify new mechanism for severe early infant epilepsy

Scientists map genes responsible for early embryonic development in humans

Research findings may help explain why drug treatments for addiction, depression are not always effective

Imetelstat drug shows promise in treating patients with myelofibrosis

Diabetes may be linked to buildup of brain tangles associated with Alzheimer’s disease

Novel approach to reduce 'bad' lipids in blood circulation

Study reveals new epigenetic mechanism underlying progression of cancer tumors

Reducing SSB intake among children and adolescents associated with greater increase in HDL-C

ISU researcher examines how supplements, resistance training improve muscle strength in older adults

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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