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Growth hormone worthwhile treatment in hypochondroplasia

Researchers report that recombinant human growth hormone can improve growth in children with hypochondroplasia.

30 Oct 2014

Promising results for low-dose insulin in paediatric diabetic ketoacidosis

Results of a randomised trial suggest that low-dose insulin may be at least as good as standard-dose insulin for the treatment of children with diabetic ketoacidosis.

30 Oct 2014

Hypocalcaemic seizure surveillance highlights UK public health policy failings

The occurrence of 91 confirmed or probable hypocalcaemic seizures in children with vitamin D deficiency over a 2-year period in the UK highlights a failure to promote appropriate supplementation.

30 Oct 2014

Paternal age increases schizophrenia risk independently of IQ

Being born to an older father increases the risk of developing a schizophrenia spectrum disorder in adulthood but has no effect on premorbid IQ, say researchers from Denmark.

30 Oct 2014

Psychotherapies offer options for treating bipolar disorder

Interpersonal and social rhythm therapy and specialist supportive care appear to be equally effective in reducing the symptoms of bipolar disorder in adolescents and young adults with the condition, study findings indicate.

30 Oct 2014

Quality of life maintained during mRCC TKI therapy

Treatment with tyrosine kinase inhibitors does not appear to significantly impair health-related quality of life in Japanese patients with metastatic renal cell carcinoma, say researchers.

30 Oct 2014

Laparoscopic renal cyroablation effective for small RCCs

Study findings support the primary use of laparoscopic renal cryoablation for long-term disease control in patients with a newly diagnosed single clinical T1a small renal mass.

30 Oct 2014

Partial nephrectomy efficacious for clinical T2 renal masses

Survival outcomes and overall complication rates of partial nephrectomy for clinical T2 renal masses are comparable to those of radical nephrectomy when the pathological staging, histology and grading of the tumours are similar, researchers report.

30 Oct 2014

Insufficient Th1 polarisation blocks RCC vaccine efficacy

A lack of a clinical response to an allogenic gene-modified renal cell cancer vaccine may be due to insufficient type 1 T-helper cell polarisation, show results of a gene expression profiling study.

30 Oct 2014

TNF-α key player in RCC progression

Tumour necrosis factor - α appears to play a key role in the promotion of invasion and metastasis in clear cell renal cell carcinomas, Japanese study findings indicate.

30 Oct 2014

Inappropriate lung cancer imaging widespread in USA

A large proportion of patients with lung cancer do not receive guideline-recommended imaging, US study data show.

30 Oct 2014

Endemic lung infection compromises lung cancer diagnosis

The accuracy of lung cancer diagnosis using 18F-fluorodeoxyglucose–positron emission tomography may be compromised in areas with endemic infectious lung diseases, research suggests.

30 Oct 2014

Adjuvant cisplatin for NSCLC raises non-cancer mortality risk

Re-analysis of data from the International Adjuvant Lung Cancer Trial indicates that cisplatin-based adjuvant chemotherapy increases the long-term risk of non-cancer mortality in patients with non-small-cell lung cancer.

30 Oct 2014

Intrathoracic radiotherapy shows potential in extensive-stage SCLC

A phase III randomised controlled trial shows that intrathoracic radiotherapy after chemotherapy significantly reduces the chances of disease progression in patients with extensive-stage small-cell lung cancer.

30 Oct 2014

ISBD Task Force examines suicide predictors

The International Society for Bipolar Disorders Task Force on Suicide has published a meta-analysis of predictors of suicide attempts and deaths.

30 Oct 2014

Physical health management below par in schizophrenia patients

The diagnosis and treatment of physical ailments in patients with schizophrenia falls below acceptable standards, shows a national audit of patients in England and Wales.

30 Oct 2014

EGFR–TKIs linked to reduced chemotherapy sensitivity in NSCLC

Epidermal growth factor receptor–tyrosine kinase inhibitors appear to significantly reduce the efficacy of subsequent chemotherapy in patients with EGFR-mutated non-small-cell lung cancer, Chinese researchers report.

30 Oct 2014

Rare neuroendocrine tumours may be misdiagnosed as Cushing’s disease

Ectopic tumours secreting corticotropin-releasing hormone and adrenocorticotropic hormone are very rare in children and can result in a misdiagnosis of Cushing’s disease, say researchers.

30 Oct 2014

Around-the-clock visitation during patient's stay improves patient satisfaction

Regardless of the circumstances, hospitalization can be a fearful thing. Patients find themselves in a new environment, surrounded by new people, new sights, new sounds - and often, the only thing that can quell that strange sense of unfamiliarity is having a loved one there to visit.

30 Oct 2014

Specific complex carbohydrates in human milk protect against Norovirus

Norovirus is the most common cause of viral epidemic gastroenteritis. About 18% of all gastroenteritis infections are caused by Norovirus affecting 267 million people worldwide every year. According to information of the Robert Koch-Institute more than 200.000 Norovirus-infections were registered in Germany during 2012 and 2013. The Centers for Disease Control and Prevention report up to 21 million Norovirus-infections per year in the USA.

30 Oct 2014