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Study: Obese youths with ALL have worse outcomes than lean counterparts

Obese youths with acute lymphoblastic leukemia (ALL) are known to have worse outcomes than their lean counterparts. To find out why, investigators at Children's Hospital Los Angeles studied patients who were obese at the time of their diagnosis with ALL to determine if body mass index (BMI) impacted response to initial chemotherapy. This response to initial chemotherapy (or induction therapy) is measured by the absence of leukemia cells in the bone marrow.

28 Oct 2014

Research breakthroughs may pave way for new drugs to fight against parasitic worm infections

Recent breakthroughs may pave the way for vaccines and new drugs for those infected by parasitic helminths. These flatworms, including tapeworms that cause hydatid diseases and neurocysticercosis, liver flukes, and blood flukes (schistosomes), infect more than 300 million people and cause approximately four million disability-adjusted life years lost due to chronic illness and death each year.

28 Oct 2014

Ugandans lack knowledge about stroke

A study published in the journal International Scholarly Research Notices Stroke found that overall knowledge about stroke in Uganda was poor, although knowing what to do for a stroke – go to the hospital – was good.

28 Oct 2014

CHOP, Temple University to jointly investigate new methods for eradicating HIV

The Children's Hospital of Philadelphia and Temple University have received a joint $4.3 million, four-year grant from the National Institute of Mental Health to investigate new methods to eradicate HIV that lurks in brain cells despite conventional antiviral treatments.

28 Oct 2014

Lowering 'bad' cholesterol may help prevent aortic valve disease, study finds

An international research team led by the Research Institute of the McGill University Health Centre and Lund University has provided new evidence that aortic valve disease may be preventable.

28 Oct 2014

New model of primary care could improve health of patients with type 2 diabetes

A new model of delivering primary care studied by Keck Medicine of the University of Southern California researchers has the potential to improve the health of patients with type 2 diabetes.

28 Oct 2014

Patients who receive chest radiation for Wilms tumor face breast cancer risk later in life

A new study has found that patients who received chest radiation for Wilms tumor, a rare childhood cancer, face an increased risk of developing breast cancer later in life due to their radiation exposure.

28 Oct 2014

Study finds that mental health disorders double heart disease, stroke risks

People facing mental health challenges are significantly more likely to have heart disease or stroke, according to a study presented today at the Canadian Cardiovascular Congress.

28 Oct 2014

Roskamp Institute Discovers New Target For Drugs To Treat Alzheimer's Disease

Scientists at the Roskamp Institute, a not-for-profit biomedical research facility specializing in Alzheimer's disease research, have isolated a key molecule that gives researchers a new drug target for the treatment of the progressive, irreversible neurological disorder.

28 Oct 2014

Pulmocide uses INTEGRA's VIAFLO Assist pipetting assistant to improve screening of novel compounds

INTEGRA reports on how respiratory drug discovery and development specialists - Pulmocide Ltd. (London, UK) are using a VIAFLO Assist pipetting assistant to enhance the productivity and reproducibility of their screening of novel compounds in a range of biological assays.

From INTEGRA Biosciences 28 Oct 2014

New research suggests that TEM5 protein may be a good target for cancer therapy

Do blood vessels that feed tumors differ from other blood vessels? Fourteen years ago, experiments designed to answer that question led to the discovery of several genes that are more active in tumor-associated blood vessels than in normal blood vessels. New research now reveals the normal function of one of those genes and suggests it could be a good target for anticancer drug therapy.

28 Oct 2014

Imaxio awarded ANR funding to improve efficacy of vaccines for seasonal influenza

Imaxio, a biopharmaceutical company specialized in vaccines, today announces that it has been awarded funding of EUR 600,000 (USD 772,000) by the French National Research Agency (Agence Nationale de la Recherche, ANR) for the OPTIVAC project 'leveraging On t-cell immune resPonse To Improve influenza VACcines'.

28 Oct 2014

Working under hot sun causes health problems for sugarcane harvesters

Hard work under hot sun causes health problems for sugar cane workers in Costa Rica, such as headache, nausea, and renal dysfunction. The presence of symptoms is also expected to increase in line with ongoing climate changes, according to a dissertation from Umeå University.

27 Oct 2014

Understanding of genomic landscape of thyroid cancer

A new comprehensive analysis of thyroid cancer from The Cancer Genome Atlas Research Network has identified markers of aggressive tumors, which could allow for better targeting of appropriate treatments to individual patients.

27 Oct 2014

Dietary cocoa flavanols can reverse age-related memory decline in healthy older adults

Dietary cocoa flavanols—naturally occurring bioactives found in cocoa—reversed age-related memory decline in healthy older adults, according to a study led by Columbia University Medical Center scientists.

27 Oct 2014

Calchan, Galapagos partner to discover and develop novel target for osteoarthritic pain

Calchan Holdings Limited, a UK company focused on the development of novel medicines based on calcium ion channel modulators, and Galapagos NV, a clinical stage biotech company focused on developing novel mode of action medicines, today announce that they have entered into a research collaboration in the area of osteoarthritis pain.

27 Oct 2014

Researchers receive EPSRC grant to develop real-time diagnostic technique for dementia

A research team from Plymouth University, together with colleagues from Swansea University, has received funding of £1M from the Engineering and Physical Sciences Research Council to develop an innovative, real-time diagnostic technique for dementia using wonder-material graphene.

27 Oct 2014

Research findings support causal association between LDL-C, aortic valve disease

In an analysis that included approximately 35,000 participants, genetic predisposition to elevated low-density lipoprotein cholesterol (LDL-C) was associated with aortic valve calcium and narrowing of the aortic valve, findings that support a causal association between LDL-C and aortic valve disease, according to a study appearing in JAMA.

27 Oct 2014

RNF43 mutation may serve as biomarker that identifies colorectal, endometrial cancer patients

Scientists say they have identified in about 20 percent of colorectal and endometrial cancers a genetic mutation that had been overlooked in recent large, comprehensive gene searches. With this discovery, the altered gene, called RNF43, now ranks as one of the most common mutations in the two cancer types.

27 Oct 2014

Engineered cells reveal changes associated with learning, memory and reward

Scientists have created cells with fluorescent dyes that change color in response to specific neurochemicals. By implanting these cells into living mammalian brains, they have shown how neurochemical signaling changes as a food reward drives learning, they report in Nature Methods online October 26.

27 Oct 2014

Medical Research News

Study: Obese youths with ALL have worse outcomes than lean counterparts

Research breakthroughs may pave way for new drugs to fight against parasitic worm infections

Ugandans lack knowledge about stroke

CHOP, Temple University to jointly investigate new methods for eradicating HIV

Lowering 'bad' cholesterol may help prevent aortic valve disease, study finds

New model of primary care could improve health of patients with type 2 diabetes

Patients who receive chest radiation for Wilms tumor face breast cancer risk later in life

Study finds that mental health disorders double heart disease, stroke risks

Roskamp Institute Discovers New Target For Drugs To Treat Alzheimer's Disease

Pulmocide uses INTEGRA's VIAFLO Assist pipetting assistant to improve screening of novel compounds

New research suggests that TEM5 protein may be a good target for cancer therapy

Imaxio awarded ANR funding to improve efficacy of vaccines for seasonal influenza

Working under hot sun causes health problems for sugarcane harvesters

Understanding of genomic landscape of thyroid cancer

Dietary cocoa flavanols can reverse age-related memory decline in healthy older adults

Calchan, Galapagos partner to discover and develop novel target for osteoarthritic pain

Researchers receive EPSRC grant to develop real-time diagnostic technique for dementia

Research findings support causal association between LDL-C, aortic valve disease

RNF43 mutation may serve as biomarker that identifies colorectal, endometrial cancer patients

Engineered cells reveal changes associated with learning, memory and reward

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