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PGC-1α protein found in muscle may contributes to the development of type 2 diabetes later in life

A Montr-al research team led by Jennifer Estall at the IRCM discovered that a protein found in muscle tissue may contribute to the development of type 2 diabetes later in life. The study's results, published in today's printed edition of the scientific journal American Journal of Physiology - Endocrinology and Metabolism, indicate that the protein could be a promising early predictor of increased diabetes risk.

15 Jan 2014

Researchers explore new strategy to defeat drug-resistant strains of malaria

Malaria is one of the most deadly infectious diseases in the world today, claiming the lives of over half a million people every year, and the recent emergence of parasites resistant to current treatments threatens to undermine efforts to control the disease. Researchers are now onto a new strategy to defeat drug-resistant strains of the parasite. Their report appears in the journal ACS Chemical Biology.

15 Jan 2014

Researchers report three-fold increase in use of minimally invasive surgery for pancreatic disease

Researchers at University of California, San Diego School of Medicine report a three-fold increase in the use of minimally invasive surgery across the nation for patients with pancreatic disease. Although adaptation of MIS for this difficult-to-reach gland is recent, the growing trend points to improved patient outcomes, such as reduced bleeding and infections. Now published online, the paper will appear in the March print edition of JAMA Surgery.

15 Jan 2014

Call for long follow-up after CIN3 treatment

Researchers from Sweden say that women who have been treated for cervical precancer should receive lifelong follow-up, after finding that their risk for dying from vaginal or cervical cancer markedly increases after the age of 60 years.

15 Jan 2014

More evidence for glutamate dysregulation in schizophrenia

Levels of glutamine, but not glutamate, are elevated in the dorsal anterior cingulate of patients with established schizophrenia, say researchers.

15 Jan 2014

Emotion regulation deficits characterize bipolar and MDD patients

Patients with bipolar disorder and major depressive disorder have increased use of maladaptive and decreased use of adaptive emotion regulation strategies, researchers report.

15 Jan 2014

Research findings provide insights into risks associated with isolated mild hyperglycemia

Despite having mild hyperglycemia for approximately 50 years, patients with a mutation in the gene encoding the enzyme glucokinase had a low prevalence of clinically significant vascular complications, findings that provide insights into the risks associated with isolated mild hyperglycemia, according to a study in the January 15 issue of JAMA.

15 Jan 2014

New stem cell study explains how breast cancer spreads

Breast cancer stem cells exist in two different states and each state plays a role in how cancer spreads, according to an international collaboration of researchers. Their finding sheds new light on the process that makes cancer a deadly disease.

15 Jan 2014

Study reveals high prevalence of TB infection among young children

A small study by investigators from the Johns Hopkins Children's Center and Byramjee Jeejeebhoy Government Medical College in India reveals high prevalence of tuberculosis infection among young children, troubling rates of disseminated disease and alarming patterns of drug resistance.

15 Jan 2014

Research identifies new way for slow release drugs

Reservoirs of pharmaceuticals could be manufactured to bind specifically to infected tissue such as cancer cells for slow, concentrated delivery of drug treatments, according to new research published in ACS Macro Letters.

15 Jan 2014

Cognigram can detect early signs of MCI and Alzheimer’s disease

For patients over the age of 50, a routine physical exam at the doctor’s office typically covers a wide spectrum of medical biomarkers with one glaring exception, cognitive health. Unless there have been unusual mental changes or challenges in their daily life, tests of a patient’s attention, memory or brain processing speed is usually not part of a check-up.

15 Jan 2014

BMH-21 chemical compound has ability to shut down a common cancer process

Johns Hopkins scientists say a previously known but little studied chemical compound targets and shuts down a common cancer process. In studies of laboratory-grown human tumor cell lines, the drug disrupted tumor cell division and prevented growth of advanced cancer cells.

15 Jan 2014

Cedars-Sinai investigators identify new molecular abnormalities in diabetic cornea

Investigators at the Cedars-Sinai Regenerative Medicine Institute have identified new molecular abnormalities in the diabetic cornea that could contribute to eye problems in affected patients. With this new knowledge, investigators aim to accelerate the process of healing and repair in damaged corneas to ultimately reverse the effects of diabetes-induced eye complications.

15 Jan 2014

New gold nanoparticle method allows for tracking studies of virus pathways in tissues

Enteroviruses are pathogenic viruses infecting humans. This group consists of polioviruses, coxsackieviruses, echoviruses and rhinoviruses. Enteroviruses are the most common causes of flu, but they also cause serious symptoms such as heart muscle infections and paralysis. Recently, enteroviruses have been linked with chronic diseases such as diabetes.

15 Jan 2014

Breast cancer cells masquerade as neurons begin to form ultimately-deadly brain tumors

Treatment and "cure" of breast cancer doesn't ensure that the disease won't spread to the brain. Too often, sometimes years after an initial diagnosis and remission, breast cancer cells are discovered growing as new tumors within the brain. Now City of Hope researchers have found how this happens.

15 Jan 2014

Research explores potential benefits of computer access to senior citizens' health

Louis Medvene, Wichita State University professor of psychology and director of the Social Relationships Research Workgroup, is exploring the potential benefits of computer access to senior citizens' health.

15 Jan 2014

New minimally invasive procedure for AF patients who are intolerant of blood-thinning medications

Sanford Heart Hospitals in Fargo and Sioux Falls now provide a new, minimally invasive procedure for atrial fibrillation (AF) patients who are intolerant of blood-thinning medications. Atrial fibrillation is a heart disorder that affects nearly 3 million adults in the United States.

15 Jan 2014

Most primary care practices have only few resources to counsel patients about weight control

Only a quarter of U.S. primary care physicians surveyed are doing a thorough job of helping patients achieve and maintain a healthy weight, finds a study in the American Journal of Health Promotion.

15 Jan 2014

More independent work environments may lead to reductions in autism symptoms

More independent work environments may lead to reductions in autism symptoms and improve daily living in adults with the disorder, according to a new study released in the Journal of Autism and Developmental Disorders.

15 Jan 2014

Researchers look at age-related differences on how memories are stored and retrieved

It's not that younger people are able to remember more than older people. Their memories seem better because they are able to retrieve them in higher definition. So says Philip Ko of Vanderbilt University in the US, in a study that sheds light on how differences in the behavioral and neural activity of younger and older adults influence the different generations' ability to store and recall memories.

15 Jan 2014

Medical Research News

PGC-1α protein found in muscle may contributes to the development of type 2 diabetes later in life

Researchers explore new strategy to defeat drug-resistant strains of malaria

Researchers report three-fold increase in use of minimally invasive surgery for pancreatic disease

Call for long follow-up after CIN3 treatment

More evidence for glutamate dysregulation in schizophrenia

Emotion regulation deficits characterize bipolar and MDD patients

Research findings provide insights into risks associated with isolated mild hyperglycemia

New stem cell study explains how breast cancer spreads

Study reveals high prevalence of TB infection among young children

Research identifies new way for slow release drugs

Cognigram can detect early signs of MCI and Alzheimer’s disease

BMH-21 chemical compound has ability to shut down a common cancer process

Cedars-Sinai investigators identify new molecular abnormalities in diabetic cornea

New gold nanoparticle method allows for tracking studies of virus pathways in tissues

Breast cancer cells masquerade as neurons begin to form ultimately-deadly brain tumors

Research explores potential benefits of computer access to senior citizens' health

New minimally invasive procedure for AF patients who are intolerant of blood-thinning medications

Most primary care practices have only few resources to counsel patients about weight control

More independent work environments may lead to reductions in autism symptoms

Researchers look at age-related differences on how memories are stored and retrieved

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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