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Scientists receive $4M grant to identify biomarker for secondary injuries associated with brain

In an effort to lower medical costs, identify patients at risk for injury, and speed patient recovery, scientists will attempt to identify a molecular signal that indicates severity of brain-injury during a $4 million, five-year federal grant to Barrow Neurological Institute at St. Joseph's Hospital and Medical Center, Phoenix Children's Hospital and the Translational Genomics Research Institute (TGen).

5 Dec 2013

Research highlights value of fathers in both neurobiology and behavior of offspring

Even with today's technology, it still takes both a male and a female to make a baby. But is it important for both parents to raise that child? Many studies have outlined the value of a mother, but few have clearly defined the importance of a father, until now.

5 Dec 2013

Study: Track-side noise may exceed 8,500% of person's daily recommended noise exposure

As an acoustical engineer, Craig Dolder - currently a graduate student at the University of Texas, Austin - knew that loud noises can damage hearing. Even so, when Canada's Formula 1 Grand Prix coincided with an Acoustical Society of America (ASA) meeting that he was attending in Montreal, Quebec, earlier this year, Dolder was drawn to the racetrack and the deafening roar of the Formula 1 engines.

5 Dec 2013

Poor sleep quality linked with mood disturbance and lower quality of life in people with obesity

A new study shows that poor sleep quality is strongly associated with mood disturbance and lower quality of life among people with extreme obesity.

5 Dec 2013

New research offers fresh insights to drug designers searching for better pain treatments

In a technical tour de force, UC San Francisco scientists have determined, at near-atomic resolution, the structure of a protein that plays a central role in the perception of pain and heat.

5 Dec 2013

Mothers, but not fathers, exhibit symptoms of depression after the death of adult son

Mothers - but not fathers - exhibited symptoms of depression and experienced declines in overall health after the death of an adult son, while the death of a daughter had no such effect on either parent, according to one of the first studies to examine the impacts of the death of an adult child on parents aged 65 and older.

5 Dec 2013

Blocking Cdh1 protein could accelerate development of new therapies targeting cancer

The laboratory of Marcos Malumbres, who is head of the Spanish National Cancer Research Centre's (CNIO) Cell Division & Cancer Group, working alongside Isabel Fari-as' team from the University of Valencia, shows, in a study published today in the journal Nature Communications, how in mice the elimination of the Cdh1 protein -a sub-unit of the APC/C complex, involved in the control of cell division-prevents cellular proliferation of rapidly dividing cells.

5 Dec 2013

Baicalin inhibits colistin sulfate-induced apoptosis of PC12 cells

Baicalin, a type of flavonoid extracted from the dried root of Scutellaria baicalensis georgi, has been shown to effectively inhibit cell apoptosis. Colistin sulfate, a cyclic cationic polypeptide antibiotic, has been shown to have renal and neurological side effects.

4 Dec 2013

UCLA researchers discover how prostate cancer stem cells evolve as the disease grows

UCLA researchers have discovered how prostate cancer stem cells evolve as the disease progresses, a finding that could help point the way to more highly targeted therapies.

4 Dec 2013

Pro-inflammatory proteins linked to obesity, metabolic syndrome in adults appear to protect young children

The first study of its kind, led by Melinda Sothern, PhD, CEP, Professor and Director of Behavioral and Community Health Sciences at LSU Health Sciences Center New Orleans School of Public Health, reveals that the same pro-inflammatory proteins linked to obesity and the metabolic syndrome in adults appear to protect children prior to puberty.

4 Dec 2013

BIDMC study shows carbon monoxide may have a role to play in treating cancer

In recent years, research has suggested that carbon monoxide, the highly toxic gas emitted from auto exhausts and faulty heating systems, can be used to treat certain inflammatory medical conditions. Now a study led by a research team at Beth Israel Deaconess Medical Center (BIDMC) shows for the first time that carbon monoxide may also have a role to play in treating cancer.

4 Dec 2013

Tet1 helps erase epigenetic imprints from genome ahead of egg, sperm development

A protein called Tet1 is partly responsible for giving primordial germ cells a clean epigenetic slate before developing into sperm and egg cells, according to a new study by researchers at Boston Children's Hospital.

4 Dec 2013

Researchers discover how PC7 protein affects certain types of cognitive performance

A team of Montr-al researchers at the IRCM led by Dr. Nabil G. Seidah, in collaboration with Dr. William C. Wetsel's team at Duke University in the United States, discovered that the protein PC7 plays a critical role in the brain by affecting certain types of cognitive performance such as anxiety, learning and emotional memory. Their results, recently published in the scientific journals Proceedings of the National Academy of Sciences (PNAS) and Nature, could have a significant impact on regulating behaviour related to anxiety disorders and trauma.

4 Dec 2013

Bipolar-specific disease management gives good returns

Diagnostic-specific management of bipolar II disorder is associated with significant clinical improvements, show findings that support the need for greater recognition of the condition.

4 Dec 2013

Lung cancer is costliest cancer in European Union

The total cost of cancer care across the European Union was an estimated € 126 billion in 2009, with lung cancer having the highest cost, at 15% of the total.

4 Dec 2013

Occupational air pollution tied to COPD mortality

People who are exposed to vapors, gases, dust, or fumes in the course of their work are at increased risk for dying from chronic obstructive pulmonary disease, a large population study reveals.

4 Dec 2013

Depression during pregnancy may affect child's mental health

Depression is a serious mental illness that has many negative consequences for sufferers. But depression among pregnant women may also have an impact on their developing babies.

4 Dec 2013

Results of national survey and benchmark study on employee healthcare benefits released

The results of a recent national survey and benchmark study on employee healthcare benefits are now available. The 2013 Healthcare Benefits Trends Benchmark Study report provides insights into the adoption of new healthcare benefits, health exchanges, wellness, and related topics. The research was sponsored by the Healthcare Trends Institute, an educational platform for employers, consumers, and other healthcare benefits stakeholders.

4 Dec 2013

Study focuses on effects of nanoparticles on eosinophils linked to inflammation

In a growing number of industries, workers are often unknowingly exposed to nanoparticles (NPs). Do they enter the body? Could they have an impact on health? Professor Denis Girard from the INRS-Institut Armand-Frappier Research Centre has had the foresight to study the potential toxicity of a wide variety of NPs with a view to setting the record straight before problems occur.

4 Dec 2013

AAAS Honors Two Tufts University faculty members as Fellows

Two faculty members at Tufts University have been elected Fellows of the American Association for the Advancement of Science (AAAS), an honor bestowed upon AAAS members by their peers. John M. Coffin and planetary scientist Samuel P. Kounaves are among 388 new Fellows recognized by AAAS based on their distinguished efforts to advance science or its applications.

4 Dec 2013

Medical Research News

Scientists receive $4M grant to identify biomarker for secondary injuries associated with brain

Research highlights value of fathers in both neurobiology and behavior of offspring

Study: Track-side noise may exceed 8,500% of person's daily recommended noise exposure

Poor sleep quality linked with mood disturbance and lower quality of life in people with obesity

New research offers fresh insights to drug designers searching for better pain treatments

Mothers, but not fathers, exhibit symptoms of depression after the death of adult son

Blocking Cdh1 protein could accelerate development of new therapies targeting cancer

Baicalin inhibits colistin sulfate-induced apoptosis of PC12 cells

UCLA researchers discover how prostate cancer stem cells evolve as the disease grows

Pro-inflammatory proteins linked to obesity, metabolic syndrome in adults appear to protect young children

BIDMC study shows carbon monoxide may have a role to play in treating cancer

Tet1 helps erase epigenetic imprints from genome ahead of egg, sperm development

Researchers discover how PC7 protein affects certain types of cognitive performance

Bipolar-specific disease management gives good returns

Lung cancer is costliest cancer in European Union

Occupational air pollution tied to COPD mortality

Depression during pregnancy may affect child's mental health

Results of national survey and benchmark study on employee healthcare benefits released

Study focuses on effects of nanoparticles on eosinophils linked to inflammation

AAAS Honors Two Tufts University faculty members as Fellows

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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