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Combinatory therapy may be effective in suppressing drug resistance in treatment of melanoma

Stand Up To Cancer (SU2C), the charitable initiative supporting ground-breaking research aimed at getting new cancer treatments to patients in an accelerated timeframe, announces that the Allan H. (Bud) and Sue Selig Stand Up To Cancer Melanoma Innovative Research Grant Recipient Roger S. Lo, M.D., Ph.D., associate professor in the Department of Medicine at the Jonsson Comprehensive Cancer Center of the University of California, Los Angeles (UCLA) has published two studies in Cancer Discovery, a journal of the American Association for Cancer Research which indicate that treatment using combinatory therapy may be effective in suppressing drug resistance in the treatment of melanoma.

21 Nov 2013

Research: New drugs show ability to rapidly shrink melanoma tumors

Melanoma is the deadliest form of skin cancer, killing more than 8,000 in the U.S. each year. Approximately 40 percent of advanced melanoma tumors are driven to grow by the presence of mutations in a gene known as the BRAF gene.

21 Nov 2013

New technique can diagnose cancer with high degree of accuracy, say researchers

A team of researchers from UCLA and Harvard University have demonstrated a technique that, by measuring the physical properties of individual cells in body fluids, can diagnose cancer with a high degree of accuracy.

21 Nov 2013

QoL, BMI predict exacerbations in Japanese COPD patients

Analysis of a cohort of Japanese chronic obstructive pulmonary disease patients with a low exacerbation frequency shows that low body mass index and poor health-related quality of life independently predict flare ups of the disease.

21 Nov 2013

Type 2 diabetes cytokine elevation places teeth at risk

Scientists have detected significant differences in the cytokine and chemokine make up of gingival crevicular fluid taken from chronic periodontitis patients with uncontrolled Type 2 diabetes and those without.

21 Nov 2013

Treatment key to averting psychosis violence after prison release

The risk for violence after the release of prisoners with sexual or violent offences is increased if they have untreated psychosis, a study shows.

21 Nov 2013

Conversion from psychotic depression to bipolar disorder explored

Danish researchers have identified a range of characteristics in people with psychotic depression that predict an increased risk for conversion to bipolar disorder.

21 Nov 2013

Keeping active reduces women’s Crohn’s risk

Regular exercise protects women against the development of Crohn’s disease, reveals research published in the BMJ.

21 Nov 2013

Unemployed men show signs of faster ageing in their DNA

Men who are unemployed for more than two years show signs of faster ageing in their DNA, a new study has found.

21 Nov 2013

New research highlights urgent need to address distress in long-term melanoma survivors

More than one-third of Queensland melanoma survivors are suffering clinically significant psychological distress, despite the high survival rate associated with the cancer.

21 Nov 2013

Attractants prevent maturing nerve cells from migrating into brain

A vision is to implant nerve precursor cells in the diseased brains of patients with Parkinson's and Huntington's diseases, whereby these cells are to assume the function of the cells that have died off.

21 Nov 2013

Study reveals benefits of bright light in treating anxiety

The bright light headset maker Valkee today announced the results of a new groundbreaking bright light study, showing statistically significant positive results in acutely alleviating anxiety symptoms. The world's first randomized, fully sham-controlled double blind trial of bright light treatment administered via ear canals brings sought-after new data to support the bright light studies carried out internationally since the 1980s.

21 Nov 2013

Brown University biologists find way to measure effects of aging

Biologists at Brown University have found a way to measure the effects of aging by watching the ebb and flow of chromatin, a structure along strands of DNA that either silences or permits gene expression. In several newly published experiments they show that gene silencing via chromatin in fruit flies declines with age.

21 Nov 2013

Kennedy Krieger Institute researchers find therapeutic benefits of virtual sailing

Researchers at the Kennedy Krieger Institute announced today the results of a pilot study demonstrating use of a virtual therapeutic sailing simulator as an important part of rehabilitation following a spinal cord injury. Published in the American Journal of Physical Medicine & Rehabilitation, findings show that using a hands-on sailing simulator over a 12-week period helped participants safely learn sailing skills in a controlled environment, ultimately improving their quality of life by gaining the ability to participate in a recreational sport.

21 Nov 2013

Researchers engineering first-ever living, three-dimensional human arrhythmic tissue

A foundational study published in top biomedical journal PNAS (Proceedings of the National Academy of Sciences) this week by researchers at the University of Toronto's Institute of Biomaterials & Biomedical Engineering and the McEwen Centre for Regenerative Medicine have identified the optimal structure and cell ratio associated with heart function - and the discovery has already led the team to another research first: the engineering of the first-ever living, three-dimensional human arrhythmic tissue.

21 Nov 2013

Safest way to manage brain AVM is to treat patient's symptoms only

Patients with a condition that causes blood vessels in the brain to form an abnormal tangle could be helped by the findings of new research.

21 Nov 2013

Vagus nerve stimulation-tone therapy safe for treating tinnitus, say UT Dallas researchers

UT Dallas researchers have demonstrated that treating tinnitus, or ringing in the ears, using vagus nerve stimulation-tone therapy is safe and brought significant improvement to some of the participants in a small clinical trial.

21 Nov 2013

Buck Institute research provides method to study sarcopenia

Our epigenome is a set of chemical switches that turn parts of our genome off and on at strategic times and locations. These switches help alter the way our cells act and are impacted by environmental factors including diet, exercise and stress. Research at the Buck Institute reveals that aging also effects the epigenome in human skeletal muscle. The study, appearing on line in Aging Cell, provides a method to study sarcopenia, the degenerative loss of muscle mass that begins in middle age.

21 Nov 2013

Covagen, TRL expand research collaboration to generate bispecific FynomAb

Covagen and Tanabe Research Laboratories U.S.A, Inc., a fully owned subsidiary of Mitsubishi Tanabe Pharma Corporation, today announced that they expanded their strategic research collaboration. MTPC and TRL have nominated a first bispecific FynomAb for formal preclinical development which triggered an undisclosed milestone payment. MTPC and TRL also exercised an option for a second bispecific FynomAb program based on the parties' research and licensing agreement signed in October 2012.

21 Nov 2013

Obese children could suffer step back in life expectancy by up to 10 years

In Mexico, overweight or obese children could suffer a step back in life expectancy by up to 10 years. According to the National Institute of Geography and Statistics (INEGI), the life expectancy in Mexico is of 73 years for women and 76 years for men.

21 Nov 2013