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Research findings could lead to new drug design for neurological diseases

A new intermediate step and unexpected enzymatic activity in a metabolic pathway in the body, which could lead to new drug design for psychiatric and neurodegenerative diseases, has been discovered by researchers at Georgia State University.

8 Jan 2015

Testosterone therapy suppresses some advanced prostate cancers, find Johns Hopkins scientists

In a surprising paradox, the male hormone testosterone, generally thought to be a feeder of prostate cancer, has been found to suppress some advanced prostate cancers and also may reverse resistance to testosterone-blocking drugs used to treat prostate cancer.

8 Jan 2015

Protecting children in advance from head injuries helps reduce brain trauma

An exhaustive analysis of data from more than 40,000 cases of brain trauma in children - published by the authoritative New England Journal of Medicine - provides convincing evidence that protecting children in advance from head injuries is the key to reducing their severity.

7 Jan 2015

Study: Synthetic triglyceride oil may provide hope for people with Huntington's disease

An early study suggests that a synthetic triglyceride oil called triheptanoin may provide hope for people with Huntington's disease. The study is published in the January 7, 2015, online issue of Neurology, the medical journal of the American Academy of Neurology.

7 Jan 2015

Using HIV drugs to treat AMD: an interview with Dr Mark Young

NRTIs are compounds which were originally developed in the 1960s as anti-cancer agents. They are similar in structure to the bases which make up DNA, and it was hoped that they would interfere with DNA replication in fast-growing cancer cells, slowing down or stopping tumour growth.

7 Jan 2015

Quadrivalent HPV vaccine cleared of multiple sclerosis risk

A study of almost 4 million girls and women allays fears that receipt of the quadrivalent human papillomavirus vaccine could increase the risk of developing multiple sclerosis, or other demyelinating disorders.

7 Jan 2015

Longitudinal course of schizophrenia negative symptoms revealed

Schizophrenia negative symptoms are relatively stable in the first year for most patients after they begin antipsychotic medication but research suggests around a quarter will experience exacerbation or relapse.

7 Jan 2015

Comorbid OCD not uncommon in bipolar disorder

Co-occurrence of obsessive compulsive disorder in patients with bipolar disorder type I is not uncommon and is associated with increased functional disability, research findings indicate.

7 Jan 2015

CET ‘feasible’ in schizophrenia patients with substance misuse

Patients with schizophrenia and comorbid substance abuse diagnoses are able to benefit from cognitive enhancement therapy, preliminary research suggests.

7 Jan 2015

Study finds unnecessary hysterectomy in 1 out of 5 cases

It is estimated that one in three women in the United States will have had a hysterectomy by the age of 60. Although the numbers of hysterectomies are decreasing, a new study of more than three thousand women in Michigan who underwent hysterectomy for benign indications reveals that alternatives to hysterectomy are being underused and that treatment guidelines are often not followed.

7 Jan 2015

McGill University researchers identify network of complex neurons in the brain

Our ability to pay attention to certain things while ignoring distractions determines how good we are at a given task, whether it is driving a car or doing brain surgery. A research team at McGill University has for the first time convincingly identified a network of neurons in a particular area of the brain, the lateral prefrontal cortex, that interact with one another to promptly filter visual information while at the same time ignoring distractions. It's a discovery with potentially far reaching implications for people who suffer from diseases such as autism, ADHD and schizophrenia.

7 Jan 2015

Researchers detect close functional link between two brain regions for 'absolute pitch'

People who have "absolute pitch" can identify notes immediately without relying on a reference tone. Intensive research is being conducted into the neuronal basis of this extraordinary ability at the University of Zurich's Department of Neuropsychology. The researchers have now detected a close functional link between the auditory cortex in the brain and the frontal lobe in these extraordinary people - a discovery that is not only important in theory, but also in practice.

7 Jan 2015

Study: Almost 40% of people with abnormal results ignore bowel cancer screening tests

Almost 40 per cent of people who have abnormal results from bowel cancer screening tests and are referred for further investigation ignore their next screening invitation two years later, according to a Cancer Research UK study published today (Tuesday) in the British Journal of Cancer.

7 Jan 2015

More insight into influence of obesity on distribution, elimination of drugs needed, say experts

Doctors and pharmacists often do not take obesity into account when prescribing medication. For this, more insight into the influence of obesity on the distribution and elimination of drugs is of the utmost importance. This is emphasized by Catherijne Knibbe in the most recent issue of the Annual Review of Pharmacology and Toxicology.

7 Jan 2015

Researchers examine ischemic complications in patients who receive flow-diverting stents

The use of flow-diverting stents to treat intracranial aneurysms appears safe and highly successful. Recently, however, there have been reports of ischemic complications occurring in brain territories supplied by the parent artery in which the stent is placed and in brain regions fed by small arterial branches whose ostia are covered by the stent.

7 Jan 2015

Personal traits may help protect police officers from PTSD symptoms

Personal traits such as resilience, satisfaction with life and a grateful disposition may help shield police officers from symptoms of post-traumatic stress disorder (PTSD) in the aftermath of a natural disaster.

7 Jan 2015

UCLA researchers develop method that defines unique stages of reprogramming skin cells

In a groundbreaking study that provides scientists with a critical new understanding of stem cell development and its role in disease, UCLA researchers at the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research led by Dr. Kathrin Plath, professor of biological chemistry, have established a first-of-its-kind methodology that defines the unique stages by which specialized cells are reprogrammed into stem cells that resemble those found in the embryo.

7 Jan 2015

People working in prisons, secure hospitals are at increased risk of developing work-related stress

People working in prisons and in secure hospitals in the UK are at considerable risk of work-related stress, exhaustion and depression. This raises serious concerns for safety.

7 Jan 2015

Real-time RT-PCR TaqMan assay helps differentiate active pulmonary TB from LTBI

One of the roadblocks to the eradication of tuberculosis (TB) is the difficulty in identifying patients with latent TB infections (LTBI). Neither the tuberculin skin test (TST) nor interferon-gamma release assays (IGRAs) are capable of distinguishing active from latent infection or predicting the chance of reactivation.

7 Jan 2015

Very small changes in blood acidity level may have detrimental impact on patients with CKD

A University of Manchester scientist has discovered that very small changes in the level of acidity in blood may have a detrimental impact on the health of patients with kidney disease.

7 Jan 2015

Medical Research News

Research findings could lead to new drug design for neurological diseases

Testosterone therapy suppresses some advanced prostate cancers, find Johns Hopkins scientists

Protecting children in advance from head injuries helps reduce brain trauma

Study: Synthetic triglyceride oil may provide hope for people with Huntington's disease

Using HIV drugs to treat AMD: an interview with Dr Mark Young

Quadrivalent HPV vaccine cleared of multiple sclerosis risk

Longitudinal course of schizophrenia negative symptoms revealed

Comorbid OCD not uncommon in bipolar disorder

CET ‘feasible’ in schizophrenia patients with substance misuse

Study finds unnecessary hysterectomy in 1 out of 5 cases

McGill University researchers identify network of complex neurons in the brain

Researchers detect close functional link between two brain regions for 'absolute pitch'

Study: Almost 40% of people with abnormal results ignore bowel cancer screening tests

More insight into influence of obesity on distribution, elimination of drugs needed, say experts

Researchers examine ischemic complications in patients who receive flow-diverting stents

Personal traits may help protect police officers from PTSD symptoms

UCLA researchers develop method that defines unique stages of reprogramming skin cells

People working in prisons, secure hospitals are at increased risk of developing work-related stress

Real-time RT-PCR TaqMan assay helps differentiate active pulmonary TB from LTBI

Very small changes in blood acidity level may have detrimental impact on patients with CKD

Extending the reach of Amperia™

Modular cleanrooms: Enhancing flexibility and compliance

Redefining control and consistency in anaerobic microbiome workflows

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