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Finding highlights new ways of treating inflammation disorders

A team led by scientists at The Scripps Research Institute (TSRI) has identified key signaling proteins in the inflammation process that contribute to the development of inflammatory diseases such as rheumatoid arthritis, psoriasis, sepsis and inflammatory bowel diseases.

11 Oct 2013

Research delves deeply into genomics of glioblastoma multiforme cases to better target disease

When The Cancer Genome Atlas launched its massively collaborative approach to organ-by-organ genomic analysis of cancers, the brain had both the benefit, and the challenge, of going first.

11 Oct 2013

People who live in coal mining regions face increased risk depression

People who live among the destructive environmental effects of mountaintop coal mining face an increased risk of major depression. The results of a study conducted in the coal mining regions of Central Appalachia that explored the relationship between psychological health and environmental degradation are published in Ecopsychology, a peer-reviewed, online journal from Mary Ann Liebert, Inc., publishers.

11 Oct 2013

Children who stutter have less grey matter in brain regions responsible for speech production

A new study by a University of Alberta researcher shows that children who stutter have less grey matter in key regions of the brain responsible for speech production than children who do not stutter.

11 Oct 2013

Researchers discover how the body's muscles accidentally fall asleep while awake

Normally muscles contract in order to support the body, but in a rare condition known as cataplexy the body's muscles "fall asleep" and become involuntarily paralyzed. Cataplexy is incapacitating because it leaves the affected individual awake, but either fully or partially paralyzed. It is one of the bizarre symptoms of the sleep disorder called narcolepsy.

11 Oct 2013

Maternal fatty acid intake linked to infant wheeze

Japanese researchers have found that high intake of certain fatty acids by pregnant women is associated with a lower risk for wheeze during infancy in their offspring.

10 Oct 2013

Palliative chemoradiation boosts survival, QoL in poor-prognosis NSCLC

C hemoradiation is superior to chemotherapy alone with respect to both survival and quality of life in patients with inoperable non-small-cell lung cancer, a phase III trial has found.

10 Oct 2013

Pregnant smoking may have mood consequences for offspring

A case–control study suggests that people have an increased risk for developing bipolar disorder if their mothers smoked during pregnancy.

10 Oct 2013

Antisocial path to violence in psychosis

People are at particular risk for violent behavior during a first episode of psychosis if they have displayed antisocial behavior since childhood, show findings from the UK National EDEN Study.

10 Oct 2013

Computer training for Parkinson’s patients improves driving performance marker

A self-administered, nonpharmalogic intervention significantly improves the useful field of view (UFOV) of patients with Parkinson’s disease, shows a randomized trial.

10 Oct 2013

Nonmotor signs aid Parkinson’s diagnosis

Physicians should account for nonmotor symptoms when diagnosing Parkinson’s disease, researchers believe.

10 Oct 2013

Cholinergic degeneration marks gait speed in Parkinson’s patients

Gait speed is preserved in patients with Parkinson’s disease who have isolated dopaminergic denervation, but reduced in those with comorbid cholinergic denervation, research shows.

10 Oct 2013

Constellation Pharmaceuticals awarded grant to facilitate study of epigenetic control of inflammation

Constellation Pharmaceuticals, Inc., a clinical-stage biopharmaceutical company in the field of epigenetics, today announced that it has been awarded a research grant in collaboration with the University of Pittsburgh School of Medicine from the Cystic Fibrosis Foundation to explore the potential use of BET bromodomain inhibitors for the control of inflammation in cystic fibrosis.

10 Oct 2013

New research shows high levels of aluminium in infant formulas

New research from Keele University shows that infant formulas are still heavily contaminated with aluminium.

10 Oct 2013

Drugs often fail to bring acromegaly under control in routine clinical practice

Over a quarter of UK patients treated for growth hormone-producing tumours do not achieve 'safe' growth hormone levels, according to a 30 year UK multi-centre study of clinical management of the rare disease acromegaly. The findings by the Society for Endocrinology UK Acromegaly Register, published in the November issue of Clinical Endocrinology, show that drugs to control acromegaly often fail to bring the disease completely under control in routine clinical practice.

10 Oct 2013

Heptares' StaR platform offers breakthrough solution to challenge associated with antibodies therapeutics

Heptares Therapeutics, the leading GPCR structure-guided drug discovery and development company, achieved the first research milestone in its antibody therapeutics alliance with MorphoSys AG (FSE: MOR; Prime Standard Segment, TecDAX), announced in February 2013.

10 Oct 2013

Running a marathon can damage heart muscle for unfit runners

Investigators who studied a group of recreational marathon runners have established that strenuous exercise such as running a marathon can damage the heart muscle. Although they found the effect is temporary and reversible, they warn that these effects are more widespread in less fit distance runners and that recreational distance runners should prepare properly before marathons.

10 Oct 2013

Charles J. Sherr to receive Prize for Scientific Excellence in Medicine

Charles J. Sherr, M.D., Ph.D., chair of the St. Jude Children's Research Hospital Department of Tumor Cell Biology and a Howard Hughes Medical Institute Investigator, has been selected to receive the 2013 Prize for Scientific Excellence in Medicine by the American-Italian Cancer Foundation.

10 Oct 2013

Recovery sleep over weekend may not reverse all effects of sleep lost during workweek

In many modern societies, adults often sacrifice sleep during the workweek to make time for other demands, then snooze longer on the weekends to recoup that lost sleep. Research has shown that even a few days of lost sleep can have adverse effects, including increased daytime sleepiness, worsened daytime performance, an increase in molecules that are a sign of inflammation in the body, and impaired blood sugar regulation.

10 Oct 2013

Transcendental Meditation technique has large effect on reducing trait anxiety, shows analysis

A new meta-analysis published today in the Journal of Alternative and Complementary Medicine (2013;19(10):1-12)1 found the Transcendental Meditation- technique (TM) has a large effect on reducing trait anxiety for people with high anxiety.

10 Oct 2013