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Researchers uncover new genetic clue that contributes to increased risk of type 2 diabetes

An international team of researchers in Mexico and the United States has uncovered a new genetic clue that contributes to an increased risk of developing type 2 diabetes, particularly the elevated risk among Mexican and other Latin American populations.

26 Dec 2013

CAC screening plays more prominent role in determining risk for heart attack and stroke

A new study shows that coronary artery calcium (CAC) screening, an assessment tool that is not currently recommended for people considered at low risk, should play a more prominent role in helping determine a person’s risk for heart attack and heart disease-related death, as well as the need for angioplasty or bypass surgery.

26 Dec 2013

Researchers complete genomic analysis of cervical cancer in two patient populations

Researchers from the Boston area, Mexico, and Norway have completed a comprehensive genomic analysis of cervical cancer in two patient populations. The study identified recurrent genetic mutations not previously found in cervical cancer, including at least one for which targeted treatments have been approved for other forms of cancer.

25 Dec 2013

Younger women with breast cancer less likely to receive radiotherapy after BCS

Radiotherapy after breast conserving surgery has been shown to reduce the risk of breast cancer recurrence. However, although younger women tend to have more aggressive tumors and have higher risks of recurrence than older BC patients, they are less likely to receive RT after BCS, according to a study published December 24 in the Journal of the National Cancer Institute. Although treatment patterns among older BC patients have been well-studied, factors affecting non-compliance among younger women are not well-known.

25 Dec 2013

Cognitive behavioral therapy reduces headache frequency, migraine-related disability in children

Among children and adolescents with chronic migraine, the use of cognitive behavioral therapy resulted in greater reductions in headache frequency and migraine-related disability compared with headache education, according to a study appearing in the December 25 issue of JAMA.

25 Dec 2013

On-site testing for HIV, STIs declines substantially between 2000 and 2011: Study

A survey of opioid treatment programs finds that the proportion offering on-site testing for human immunodeficiency virus and sexually transmitted infections declined substantially between 2000 and 2011, despite guidelines recommending routine opt-out HIV testing in all health care settings, according to a study appearing in the December 25 issue of JAMA.

25 Dec 2013

Antidepressant nortriptyline does not improve overall symptoms in patients with idiopathic gastroparesis

Among patients with idiopathic (of unknown cause) gastroparesis, use of the antidepressant nortriptyline compared with placebo for 15 weeks did not result in improvement in overall symptoms, according to a study appearing in the December 25 issue of JAMA.

25 Dec 2013

Diflunisal drug reduces neurological decline in patients with familial transthyretin amyloidosis

A recent study led by researchers from the Amyloidosis Center at Boston University School of Medicine and Boston Medical Center demonstrates that diflunisal, a generic anti-inflammatory drug, successfully reduced neurological decline and preserved the quality of life in patients with familial transthyretin amyloidosis. Diflunisal is an inexpensive and safe medication marketed over the past 40 years for arthritis and pain.

25 Dec 2013

Prolonged exposure therapy shows greater success for treating adolescent PTSD patients

Researchers at Penn Medicine report in the December 25 issue of JAMA that a modified form of prolonged exposure therapy - in which patients revisit and recount aloud their trauma-related thoughts, feelings and situations - shows greater success than supportive counseling for treating adolescent PTSD patients who have been sexually abused.

25 Dec 2013

Research shows that human brains stumble on even the simplest rule-based calculations

Even scientists are fond of thinking of the human brain as a computer, following sets of rules to communicate, make decisions and find a meal.

24 Dec 2013

Chinese experts publish consensus on spine and spinal cord injury

The early management of acute thoracolumbar spine and spinal cord injury is one of the most difficult tasks when treating trauma cases. To standardize the evaluation and treatment of acute thoracolumbar spinal injury, the Chinese Association of Spine and Spinal Cord Injury organized a group of Chinese experts to collectively discuss the draft of "An Expert Consensus on the Evaluation and Treatment of Acute Thoracolumbar Spine and Spinal Cord Injury".

24 Dec 2013

Hypoxic preconditioning has protective effects against acute cerebral infarction

Hypoxic preconditioning has been shown to have protective effects against acute cerebral infarction. To investigate the protective mechanisms of hypoxic preconditioning in relation to its effects on angiogenesis, Prof. Xunming Ji and team from Xuanwu Hospital, Capital Medical University in China induced a photochemical model of cerebral infarction in an inbred line of mice (BALB/c) which were exposed to hypoxic preconditioning prior to model establishment.

24 Dec 2013

Study: Antidepressants not effective for bipolar disorder treatment

The use of antidepressants in the treatment of bipolar disorder remains controversial. Some studies and treatment guidelines suggest that antidepressant treatment for bipolar disorder may have the potential to increase the manic switch, while others recommend short-term antidepressant treatment and early discontinuation.

24 Dec 2013

Cell transplantation, gene therapy combination to open new therapeutic avenues for Alzheimer's disease

In a recent study published in the Neural Regeneration Research (Vol. 8, No. 33, 2013), Prof. Feng Li and team from Zhongshan School of Medicine, Sun Yat-sen University in China, synthesized a 19-nt oligonucleotide targeting BACE1, the key enzyme in amyloid beta protein (Aβ) production, and introduced it into the pSilenCircle vector to construct a short hairpin (shRNA) expression plasmid against the BACE1 gene.

24 Dec 2013

Study explores how genetic sequencing can help fight new strains of flu

Published in the Journal Proceedings of the National Academy of Sciences, senior author, Associate Professor Katherine Kedzierska from the Department of Microbiology and Immunology said that being able to predict which patients will be more susceptible to the emerging influenza strain, will allow clinicians to better manage an early intervention strategy.

24 Dec 2013

Healthcare workers' hands contaminated with C. difficile after routine care, study shows

A new study finds nearly one in four healthcare workers' hands were contaminated with Clostridium difficile spores after routine care of patients infected with the bacteria. The study was published in the January issue of Infection Control and Hospital Epidemiology, the journal of the Society for Healthcare Epidemiology of America.

24 Dec 2013

Medical Research News

Researchers uncover new genetic clue that contributes to increased risk of type 2 diabetes

CAC screening plays more prominent role in determining risk for heart attack and stroke

Researchers complete genomic analysis of cervical cancer in two patient populations

Younger women with breast cancer less likely to receive radiotherapy after BCS

Cognitive behavioral therapy reduces headache frequency, migraine-related disability in children

On-site testing for HIV, STIs declines substantially between 2000 and 2011: Study

Antidepressant nortriptyline does not improve overall symptoms in patients with idiopathic gastroparesis

Diflunisal drug reduces neurological decline in patients with familial transthyretin amyloidosis

Prolonged exposure therapy shows greater success for treating adolescent PTSD patients

Research shows that human brains stumble on even the simplest rule-based calculations

Chinese experts publish consensus on spine and spinal cord injury

Hypoxic preconditioning has protective effects against acute cerebral infarction

Study: Antidepressants not effective for bipolar disorder treatment

Cell transplantation, gene therapy combination to open new therapeutic avenues for Alzheimer's disease

Study explores how genetic sequencing can help fight new strains of flu

Healthcare workers' hands contaminated with C. difficile after routine care, study shows

Asthma link to mood disorders strengthened

Young women more likely to have negative urodynamics experience

Duration of common pediatric respiratory infections estimated

Schizophrenia brain marker matches genetic risk

Clue's CEO Rhiannon White on the Future of Femtech and PCOS

Freezing Point Osmometry in Life Science Applications

Precision in every drop: Inside Hamilton’s syringe technology

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