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Cell-free DNA analysis allows noninvasive tumour genotype monitoring

Noninvasive tumour genotyping using cell-free plasma DNA analysis is feasible, say US researchers who believe the technique will aid patient diagnosis and monitoring.

24 Mar 2014

‘Residual risk’ concern for treated Japanese hypertension patients

Physicians should be alert to other sources of cardiovascular risk in patients with hypertension, even if they are receiving optimal antihypertensive treatment, say Japanese researchers.

24 Mar 2014

Tobacco smoking increases risk of recurrent TB, shows study

Research published today provides critical new insight on the harmful links between smoking tobacco and developing tuberculosis (TB).

24 Mar 2014

New method can identify cancer's visible precursors with 97% certainty

Pancreatic cancer is often detected at a late stage, which results in poor prognosis and limited treatment options. Researchers at The University od Gothenburg, Sweden, have now developed a method which identifies the cancer's visible precursors with 97% certainty. The method, which is expected to aid in the early discovery of the cancer as well as minimize the risk of unnecessary surgery, may be introduced in patient care within five years.

24 Mar 2014

Study examines events that lead to sepsis by Streptococcus pneumoniae

An international team of academics, including Professor Marco Oggioni from the University of Leicester's Department of Genetics, has studied how localised infections can turn into the dangerous systematic disease sepsis - and has identified for the first time through genetic evidence that a single bacteria could be the cause.

24 Mar 2014

Cumulative amount of specific gene products affects changes in cell fate, say researchers

Johns Hopkins biologists have discovered that when biological signals hit cells in rhythmic waves, the magnitude of the cells' response can depend on the number of signaling cycles — not their strength or duration. Because such so-called “oscillating signaling cycles” are common in many biological systems, the scientists expect their findings in single-celled organisms to help explain the molecular workings of phenomena such as tissue and organ formation and fundamental forms of learning.

24 Mar 2014

Breastfeeding increases prevalence of Lactobacilli and Bifidobacteria in infants

Breastfeeding until at least nine months of age increases prevalence in the gastrointestinal tract of Lactobacilli and Bifidobacteria, species which are known to contribute to development of a healthy immune system, according to a paper describing the establishment of the intestinal microbiota during the first three years of life.

24 Mar 2014

Research findings may be beneficial for creation of purer HSC lines for clinical treatments

Hematopoietic stem cells are now routinely used to treat patients with cancers and other disorders of the blood and immune systems, but researchers knew little about the progenitor cells that give rise to them during embryonic development.

24 Mar 2014

DUF1220 protein domain also linked to severity of autism

The same gene family that may have helped the human brain become larger and more complex than in any other animal also is linked to the severity of autism, according to new research from the University of Colorado Anschutz Medical Campus.

24 Mar 2014

Drugs fail to "wake up" dormant reservoirs of HIV inside immune system T cells

Scientists at Johns Hopkins report that compounds they hoped would "wake up" dormant reservoirs of HIV inside immune system T cells - a strategy designed to reverse latency and make the cells vulnerable to destruction - have failed to do so in laboratory tests of such white blood cells taken directly from patients infected with HIV.

24 Mar 2014

New way to make large concentrations of skeletal muscle cells from human stem cells

As stem cells continue their gradual transition from the lab to the clinic, a research group at the University of Wisconsin-Madison has discovered a new way to make large concentrations of skeletal muscle cells and muscle progenitors from human stem cells.

24 Mar 2014

New insight into germline EGFR T790M mutation in familial non-small cell lung cancer

Two studies are providing new insight into germline epidermal growth factor receptor (EGFR) T790M mutation in familial non-small cell lung cancer (NSCLC). The findings suggest the need for tailored approaches for early detection and treatment, as well as for genetic testing to identify carriers.

24 Mar 2014

FDA approves Xolair for treatment of chronic idiopathic urticaria

Genentech, a member of the Roche Group, today announced that the U.S. Food and Drug Administration approved Xolair (omalizumab) for the treatment of chronic idiopathic urticaria, a form of chronic hives.

24 Mar 2014

Climate change could increase death rates in London and southeast England, scientists predict

Warmer summers brought on by climate change will cause more deaths in London and southeast England than the rest of the country, scientists predict.

24 Mar 2014

Study: Role of alcohol in U.S. traffic deaths may be underreported on death certificates

It's no secret that drinking and driving can be a deadly mix. But the role of alcohol in U.S. traffic deaths may be substantially underreported on death certificates, according to a study in the March issue of the Journal of Studies on Alcohol and Drugs.

24 Mar 2014

Study to develop novel antibacterial orthodontic bracket cement incorporating DMADDM

Today, at the 43rd Annual Meeting & Exhibition of the American Association for Dental Research (AADR), held in conjunction with the 38th Annual Meeting of the Canadian Association for Dental Research, Mary Anne Sampaio de Melo, from the University of Maryland, Baltimore, will present a research study titled "Antibacterial Orthodontic Cement Containing a Quaternary Ammonium Monomer Dimethylaminododecyl Methacrylate."

24 Mar 2014

New national research consortium focuses on better drug therapies for viral infections

Viral infections with limited or no treatment options can pose a major global health threat, but a new national research consortium centered at the University of Alabama at Birmingham is focused on the discovery of new and better drug therapies as these viruses emerge.

24 Mar 2014

New book "Near-Death Experiences" explores controversial topic with historical reports

In popular understanding, the expression "near-death experience" refers to the transition between the states of life and death. But how should such experiences be interpreted? Are they verifiable with scientific methods? If so, how can they be explained? Attempting to relate matters of scientific knowledge to subjective experience and the realm of belief is a difficult balancing act, and has led to a variety of approaches to the topic.

24 Mar 2014

Researchers developing new medication to tackle river blindness and elephantiasis

Researchers are developing new drug treatments to tackle river blindness and elephantiasis, which affect up to 150 million people across the world.

24 Mar 2014

CUMC researchers devise new system for classifying periodontal disease

Researchers at Columbia University Medical Center have devised a new system for classifying periodontal disease based on the genetic signature of affected tissue, rather than on clinical signs and symptoms. The new classification system, the first of its kind, may allow for earlier detection and more individualized treatment of severe periodontitis, before loss of teeth and supportive bone occurs.

24 Mar 2014

Medical Research News

Cell-free DNA analysis allows noninvasive tumour genotype monitoring

‘Residual risk’ concern for treated Japanese hypertension patients

Tobacco smoking increases risk of recurrent TB, shows study

New method can identify cancer's visible precursors with 97% certainty

Study examines events that lead to sepsis by Streptococcus pneumoniae

Cumulative amount of specific gene products affects changes in cell fate, say researchers

Breastfeeding increases prevalence of Lactobacilli and Bifidobacteria in infants

Research findings may be beneficial for creation of purer HSC lines for clinical treatments

DUF1220 protein domain also linked to severity of autism

Drugs fail to "wake up" dormant reservoirs of HIV inside immune system T cells

New way to make large concentrations of skeletal muscle cells from human stem cells

New insight into germline EGFR T790M mutation in familial non-small cell lung cancer

FDA approves Xolair for treatment of chronic idiopathic urticaria

Climate change could increase death rates in London and southeast England, scientists predict

Study: Role of alcohol in U.S. traffic deaths may be underreported on death certificates

Study to develop novel antibacterial orthodontic bracket cement incorporating DMADDM

New national research consortium focuses on better drug therapies for viral infections

New book "Near-Death Experiences" explores controversial topic with historical reports

Researchers developing new medication to tackle river blindness and elephantiasis

CUMC researchers devise new system for classifying periodontal disease

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