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NYU Langone Medical Center researchers find link between gut bacteria and colorectal cancer

In one of the largest epidemiological studies of human gut bacteria and colorectal cancer ever conducted, a team of researchers at NYU Langone Medical Center has found a clear association between gut bacteria and colorectal cancer. The study, published today in the Journal of the National Cancer Institute, discovered that colorectal cancer patients had fewer beneficial bacteria and more harmful bacteria than people without the disease.

6 Dec 2013

Kolltan Pharmaceuticals signs license agreement with University of Toronto for novel anti-KIT antibodies

Kolltan Pharmaceuticals, a privately held biopharmaceutical company, today announced the Company has signed a license agreement with the University of Toronto for novel anti-KIT receptor tyrosine kinase antibodies identified in the laboratories of Dr. Sachdev Sidhu at the University of Toronto and the laboratory of Dr. Joseph Schlessinger of Yale University.

6 Dec 2013

Maternal weight issues spell wheezing trouble for children

High maternal weight and gestational weight gain are independently associated with an increased risk for wheezing in preschool age children, a Dutch study has found.

6 Dec 2013

Brain network disruption crosses psychosis diagnostic boundaries

Disruption of cortical information processing occurs in patients with psychosis regardless of whether they have a psychotic or affective diagnosis, research shows.

6 Dec 2013

Inflexible thinking in ADHD blamed on bipolar disorder

Impaired cognitive flexibility in patients with attention deficit hyperactivity disorder (ADHD) may be entirely due to the presence of comorbid bipolar disorder, say researchers.

6 Dec 2013

ALS TDI forms research partnership with Neurimmune to advance potential treatments for ALS

The ALS Therapy Development Institute (ALS TDI), together with its wholly-owned subsidiary, Anelixis Therapeutics, announced today that it has formed a research partnership with Neurimmune to advance potential treatments for ALS, also known as Lou Gehrig's disease.

6 Dec 2013

New research finds that H7N9 still mainly adapted for infecting birds, not humans

Avian influenza virus H7N9, which killed several dozen people in China earlier this year, has not yet acquired the changes needed to infect humans easily, according to a new study by scientists at The Scripps Research Institute. In contrast to some initial studies that had suggested that H7N9 poses an imminent risk of a global pandemic, the new research found, based on analyses of virus samples from the Chinese outbreak, that H7N9 is still mainly adapted for infecting birds, not humans.

6 Dec 2013

Researchers illuminate inner workings of enzymes placed inside the outer envelopes of cells

For what is believed to be the first time, researchers at The Johns Hopkins University have illuminated the inner workings of an important class of enzymes located inside the outer envelopes of cells. Much to their surprise, they report, these protein cutters, called rhomboid proteases, are entirely different than nearly every other type of enzyme studied, showing no attraction to the proteins they cut and being extremely slow in making their cuts.

6 Dec 2013

Study uncovers novel mechanism by which glioblastoma evades targeted therapies

A Ludwig Cancer Research study has uncovered an entirely novel mechanism by which glioblastoma, the most common kind of brain cancer, evades targeted therapies. Published in the current issue of the journal Science, the paper describes how GBM tumor cells essentially hide the signaling molecule targeted by such therapies, adding a layer of complexity to current models of drug resistance in cancer.

6 Dec 2013

Low vitamin D levels: Not a cause but a consequence of ill health

A comprehensive review of the evidence suggests that low vitamin D levels are not a cause but a consequence of ill health, casting strong doubt on the value of vitamin D supplements to protect against acute and chronic disorders such as cancer, cardiovascular disease, diabetes, Parkinson’s disease, and even death.

6 Dec 2013

New project aims to reduce animal testing for drug development

Researchers at the University of East Anglia are launching a new project to develop methods which could one-day decrease the use of rats and mice in pharmaceutical testing.

6 Dec 2013

Scientists test affected human nerve cells to foretell efficacy of Alzheimer drugs

Why do certain Alzheimer medications work in animal models but not in clinical trials in humans? A research team from the University of Bonn and the biomedical enterprise LIFE & BRAIN GmbH has been able to show that results of established test methods with animal models and cell lines used up until now can hardly be translated to the processes in the human brain. Drug testing should therefore be conducted with human nerve cells, conclude the scientists.

6 Dec 2013

Central analgesic mechanism of acupuncture for treating migraine remains poorly understood

The central analgesic mechanism of acupuncture for migraine remains poorly understood. Acupuncture has been shown to become a recommended treatment for migraine sufferers.

6 Dec 2013

Study identifies specific DCPR syndromes that could affect obesity

A study published in the current issue of Psychotherapy and Psychosomatics has applied diagnostic criteria for psychosomatic syndromes to a sample of patients with morbid obesity.

6 Dec 2013

Innovative DNA engineering technique discovers potential functions hidden within bacterial genomes

A group of University of Illinois researchers, led by Centennial Chair Professor of the Department of Chemical and Biomolecular Engineering Huimin Zhao, has demonstrated the use of an innovative DNA engineering technique to discover potentially valuable functions hidden within bacterial genomes.

6 Dec 2013

Researchers update extensive toxicology database to track information about drugs toxic effects

Sometimes the cure can be worse than the disease. Pharmaceutical drugs are known for their potential side effects, and an important aspect of personalized medicine is to tailor therapies to individuals to reduce the chances of adverse events.

6 Dec 2013

Study reports new links between brain cell activity and choices where two options have equal appeal

Life presents us with choices all the time: salad or pizza for lunch? Tea or coffee afterward? How we make these everyday decisions has been a topic of great interest to economists, who have devised theories about how we assign values to our options and use those values to make decisions.

6 Dec 2013

Understanding biochemical mechanisms associated with memory formation

A discovery by a research team led by Dr. Ryohei Yasuda at the Max Planck Florida Institute for Neuroscience has significantly advanced basic understanding of biochemical mechanisms associated with how memories are formed.

6 Dec 2013

New studies examine role of hospitals and other health care facilities on nursing reforms

Two new studies by researchers at the George Washington University School of Public Health and Health Services examine how well hospitals and other health care facilities are doing when it comes to a call to reform the nursing profession. A 2010 Institute of Medicine report warned that the nursing profession must change or it would not be able to meet the growing demands that are emerging as a result of health reform, new technologies and an aging population.

6 Dec 2013

Return to play on the same day after sports concussions not recommended

Any athlete with concussion symptoms should not be allowed to return to play on the same day, according to the latest consensus statement on sports-related concussion. The updated guidelines are summarized in Neurosurgery, official journal of the Congress of Neurological Surgeons. The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health.

6 Dec 2013

Medical Research News

NYU Langone Medical Center researchers find link between gut bacteria and colorectal cancer

Kolltan Pharmaceuticals signs license agreement with University of Toronto for novel anti-KIT antibodies

Maternal weight issues spell wheezing trouble for children

Brain network disruption crosses psychosis diagnostic boundaries

Inflexible thinking in ADHD blamed on bipolar disorder

ALS TDI forms research partnership with Neurimmune to advance potential treatments for ALS

New research finds that H7N9 still mainly adapted for infecting birds, not humans

Researchers illuminate inner workings of enzymes placed inside the outer envelopes of cells

Study uncovers novel mechanism by which glioblastoma evades targeted therapies

Low vitamin D levels: Not a cause but a consequence of ill health

New project aims to reduce animal testing for drug development

Scientists test affected human nerve cells to foretell efficacy of Alzheimer drugs

Central analgesic mechanism of acupuncture for treating migraine remains poorly understood

Study identifies specific DCPR syndromes that could affect obesity

Innovative DNA engineering technique discovers potential functions hidden within bacterial genomes

Researchers update extensive toxicology database to track information about drugs toxic effects

Study reports new links between brain cell activity and choices where two options have equal appeal

Understanding biochemical mechanisms associated with memory formation

New studies examine role of hospitals and other health care facilities on nursing reforms

Return to play on the same day after sports concussions not recommended

Clue's CEO Rhiannon White on the Future of Femtech and PCOS

Freezing Point Osmometry in Life Science Applications

Precision in every drop: Inside Hamilton’s syringe technology

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