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Targeted therapy prevents rare neurodevelopmental disorder seizures

Rapamycin treatment reduces seizure frequency and improves receptive language in patients with polyhydramnios, megalencephaly, and symptomatic epilepsy syndrome, or Pretzel syndrome, a study finds.

29 Apr 2013

Educational cartoon boosts worm infection prevention

Researchers in China have found that a health education package targeted at schoolchildren can improve hygiene behaviors and reduce the incidence of soil-transmitted helminth infection.

29 Apr 2013

Dental problems create substantial burden

Over 40 million hours are lost each year due to dental problems and their treatment in the Canadian population, study findings indicate.

29 Apr 2013

Organic pollutants increase nephropathy risk in diabetes

Individuals with diabetes may reduce their risk for developing nephropathy if they minimize their exposure to persistent organic pollutants, suggest researchers.

29 Apr 2013

Laparoscopic radical nephropathy effective for advanced renal masses

Laparoscopic radical nephrectomy is an effective treatment approach for individuals with renal cell carcinoma who have larger or more advanced renal masses, report researchers.

29 Apr 2013

MRSA circulation among children greatest in hospitals

The hospital environment remains the most common source of methicillin-resistant Staphylococcus aureus bacteria, show results from a systematic review and meta-analysis looking at nasal colonization in different groups of children.

29 Apr 2013

Continuous monitoring flags acute compartment syndrome

Continuous intracompartmental pressure monitoring is highly accurate for the detection of acute compartment syndrome after tibial diaphyseal fracture, say UK researchers who believe it may allow diagnosis before signs and symptoms occur.

29 Apr 2013

IL-1 antagonist relieves dry eyes

Clinical trial results point to a role for interleukin-1 targeted agents for the treatment of dry eye disease associated with meibomian gland dysfunction.

29 Apr 2013

Biventricular pacing best in atrioventricular block patients

Use of biventricular rather than conventional right ventricular pacing results in better clinical outcomes in patients who have heart failure with atrioventricular block and left ventricular systolic dysfunction, show the results of BLOCK HF.

29 Apr 2013

New risk classification system proposed for prostate cancer

US researchers have put forward a risk stratification system for patients with intermediate-risk prostate cancer undergoing dose-escalated external-beam radiation therapy.

29 Apr 2013

Hypertensive patients may need firm dietary advice

People who have dyslipidemia or are overweight adopt healthier diets than those without, whereas patients with hypertension persist with some unhealthy eating patterns, study results show.

29 Apr 2013

Geriatric focus cuts hospital costs

An Acute Care for Elders unit with a focus on identifying and treating geriatric syndromes significantly reduces costs and 30-day readmissions for elderly patients, a study finds.

29 Apr 2013

Kidney disease screening needs rethink in hypertension

The standard approach to detecting chronic kidney disease fails to spot the condition in about a quarter of patients with hypertension, a study suggests.

29 Apr 2013

Skin cancer may increase subsequent primary malignancy risk

Research suggests that people with non-melanoma skin cancer are at moderately increased risk for developing other primary malignancies in the future, particularly breast and lung cancer and melanoma.

29 Apr 2013

Religiosity may influence depression, QoL in bipolar disorder

Results from a Brazilian study suggest that higher levels of intrinsic religiosity are associated with fewer depressive symptoms and increased quality of life in patients with bipolar disorder.

29 Apr 2013

Delayed psychosis treatment harms chance of success

The longer patients with first-episode psychosis go untreated, the less likely they are to achieve remission within a year of starting treatment, report researchers.

29 Apr 2013

Smokefree laws reduce adult asthma admissions

Results from a UK study show that legislation banning smoking in the workplace and enclosed public spaces significantly reduces emergency hospital admissions for asthma among adults.

29 Apr 2013

IP-10 and neopterin show promise as biomarkers for lung disease exacerbations

Australian researchers have identified interferon-γ inducible protein-10 and neopterin as promising sputum markers of acute exacerbations of obstructive lung disease.

29 Apr 2013

Specific inflammatory pattern found in patients with pneumonia and COPD

Patients with community-acquired pneumonia on a background of chronic obstructive pulmonary disease have a different early inflammatory pattern than patients with CAP only, a prospective study shows.

29 Apr 2013

Undetected arrhythmia could underlie some wake-up strokes

Unrecognized atrial fibrillation could be a cause of some wake-up strokes, say researchers who found an increased prevalence of the arrhythmia in patients who had stroke symptoms on waking.

29 Apr 2013