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Medical researchers discover structure of potential drug target for rare genetic disease

Medical researchers at the University of Alberta have discovered the structure of a potential drug target for a rare genetic disease, paving the way for an alternative treatment for the condition.

15 Nov 2013

Annexin A5 protein may have therapeutic potential for treatment of sepsis

Sepsis is the leading cause of in-hospital death and there is no specific treatment for it. Now, research led by Dr. Qingping Feng of Western University (London, Canada) suggests a protein called recombinant human annexin A5 may have therapeutic potential for the treatment of this disease. The paper is published in advance, online in Critical Care Medicine.

15 Nov 2013

When schools adopt healthful nutrition policies and practices, kids' diets improve

When schools adopt healthful nutrition policies and practices, kids' diets improve. According to new research led by Michigan State University and published in the current issue of Childhood Obesity, when schools offered snacks in lunchtime a la carte or vending that were mostly or entirely healthful, students responded with improvements in their diets, said Katherine Alaimo, MSU associate professor of food, science and human nutrition.

15 Nov 2013

Spirituality in teens linked with increased positive social behaviors, reduced narcissism

If the spirit is truly willing, perhaps the flesh is not so weak, after all. Increased spirituality in teens undergoing substance abuse treatment is associated with greater likelihood of abstinence (as measured by toxicology screens), increased positive social behaviors, and reduced narcissism, according to a study by researchers from The University of Akron, Case Western Reserve University (CWRU) and Baylor University.

15 Nov 2013

Dermalogix awarded SBIR Phase II grant to develop topical drug candidate for atopic dermatitis

Signum Dermalogix, Inc. announced that the National Institute of Arthritis and Musculoskeletal and Skin Diseases awarded the company a Small Business Innovation Research Phase II grant totaling $1.6 million for the development of a topical drug candidate for atopic dermatitis.

15 Nov 2013

Global Genomics Group, Metabolon partner to discover novel targets for cardiovascular diseases

Global Genomics Group and Metabolon today announced that they have entered into a collaboration agreement to investigate biological networks and pathways in order to discover novel biomarkers and pharmaceutical targets for cardiovascular diseases.

15 Nov 2013

Findings provide insights into the factors that affect surgeons’ reactions to major surgical complications

Many surgeons are seriously affected on an emotional level by major surgical complications, and they often feel that institutional support is inadequate. Those are among the conclusions of a small study published recently in the BJS (British Journal of Surgery).

14 Nov 2013

LLN spirometry inadequate to detect airflow obstruction

Research published in Thorax indicates that use of a lower limit of normal spirometric threshold fails to identify a number of patients with airflow obstruction and chronic obstructive pulmonary disease.

14 Nov 2013

Gray matter changes reflect psychosis burden

Changes in gray matter volume may be associated with psychosis burden rather than clinical diagnosis, research suggests.

14 Nov 2013

Men’s cognitive advantage maintained in early bipolar disorder

Patients in the early stages of bipolar disorder show the same gender differences in cognitive functioning as mentally healthy individuals, findings from the STOP-EM trial show.

14 Nov 2013

Parkinson’s biomarker could be only skin deep

Deposits of α-synuclein in cutaneous nerves could represent a noninvasive biomarker for Parkinson’s disease, say researchers.

14 Nov 2013

Screening for nonmotor symptoms in early Parkinson’s urged

Nonmotor symptoms have a substantial impact on the health-related quality of life of patients with early Parkinson’s disease, research shows.

14 Nov 2013

Depression link to Parkinson’s risk bolstered

A large retrospective study supports the notion that depression may be an independent risk factor for Parkinson’s disease.

14 Nov 2013

Diagnosing influenza with rapid tests leads to more efficient care

When patients in the emergency department (ED) are diagnosed with influenza by means of a rapid test, they get fewer unnecessary antibiotics, are prescribed antiviral medications more frequently, and have fewer additional lab tests compared to patients diagnosed with influenza without testing, according to a new study. Published online in the Journal of the Pediatrics Infectious Diseases Society, the findings suggest that diagnosing influenza with a rapid diagnostic test leads to more appropriate, specific, and efficient care.

14 Nov 2013

Severe sepsis mortality rates decrease over the past 20 years

A recent study from Boston University School of Medicine and Boston Medical Center shows a significant decrease in severe sepsis mortality rates over the past 20 years. Looking at data from patients with severe sepsis enrolled in clinical trials, researchers found that in-hospital mortality rates decreased from 47 percent between 1991 and 1995 to 29 percent between 2006 and 2009, a time period when no new pharmacological treatments were developed for severe sepsis.

14 Nov 2013

Researchers generate most complete genome sequences from single cells and individual neurons

Researchers led by bioengineers at the University of California, San Diego have generated the most complete genome sequences from single E. coli cells and individual neurons from the human brain. The breakthrough comes from a new single-cell genome sequencing technique that confines genome amplification to fluid-filled wells with a volume of just 12 nanoliters.

14 Nov 2013

New research devises effective way to evaluate severity of pulmonary hypertension

An aim to improve the outlook for people suffering from pulmonary hypertension is the focus of research at Griffith University.

14 Nov 2013

TAILORED-Treatment project to increase effectiveness of antibiotics receives EU funding

The European Union has funded a 4 year project called TAILORED-Treatment with € 6.000.000,-. The main goal of TAILORED -Treatment is to establish a strategy that can be used to increase the effectiveness of antibiotic treatment, reduce any potential side-effects of therapy, and help limit the emergence of antimicrobial resistance in hospitalized children and adults. The project will be coordinated by Erasmus MC, Rotterdam, the Netherlands.

14 Nov 2013

Study reveals how cocaine permanently damages proteins in the body

A new study on cocaine, the notorious white powder illegally snorted, injected or smoked by nearly 2 million Americans, details how it may permanently damage proteins in the body. That information, gleaned from laboratory tests, could be used to potentially detect the drug in biofluids for weeks or months - instead of days - after use, say scientists. The findings, which appear in the ACS journal Chemical Research in Toxicology, could also help explain cocaine's long-term health effects.

14 Nov 2013

Research findings call for a rethinking of cancer genetics

Johns Hopkins researchers report that the deletion of any single gene in yeast cells puts pressure on the organism’s genome to compensate, leading to a mutation in another gene. Their discovery, which is likely applicable to human genetics because of the way DNA is conserved across species, could have significant consequences for the way genetic analysis is done in cancer and other areas of research, they say.

14 Nov 2013

Medical Research News

Medical researchers discover structure of potential drug target for rare genetic disease

Annexin A5 protein may have therapeutic potential for treatment of sepsis

When schools adopt healthful nutrition policies and practices, kids' diets improve

Spirituality in teens linked with increased positive social behaviors, reduced narcissism

Dermalogix awarded SBIR Phase II grant to develop topical drug candidate for atopic dermatitis

Global Genomics Group, Metabolon partner to discover novel targets for cardiovascular diseases

Findings provide insights into the factors that affect surgeons’ reactions to major surgical complications

LLN spirometry inadequate to detect airflow obstruction

Gray matter changes reflect psychosis burden

Men’s cognitive advantage maintained in early bipolar disorder

Parkinson’s biomarker could be only skin deep

Screening for nonmotor symptoms in early Parkinson’s urged

Depression link to Parkinson’s risk bolstered

Diagnosing influenza with rapid tests leads to more efficient care

Severe sepsis mortality rates decrease over the past 20 years

Researchers generate most complete genome sequences from single cells and individual neurons

New research devises effective way to evaluate severity of pulmonary hypertension

TAILORED-Treatment project to increase effectiveness of antibiotics receives EU funding

Study reveals how cocaine permanently damages proteins in the body

Research findings call for a rethinking of cancer genetics

Clue's CEO Rhiannon White on the Future of Femtech and PCOS

Freezing Point Osmometry in Life Science Applications

Precision in every drop: Inside Hamilton’s syringe technology

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