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Polyplus-transfection grants research license to NIH for PEI-mediated transfection applications

Polyplus-transfection SA, a privately-held company developing innovative technologies for molecular and cellular biology, announces today that it has granted two agencies of the United States National Institutes of Health a non-exclusive, research license to use Polyethylenimine (PEI) for in vitro transfection applications. The two agencies are the National Institute of Allergy and Infectious Diseases and the National Cancer Institute.

17 Feb 2014

Mini-sling partially successful for stress urinary incontinence

A mini-sling that requires a single incision may be a viable alternative to the “gold standard” transobturator midurethral sling for the treatment of stress urinary incontinence, a randomised controlled trial has found.

17 Feb 2014

Sleep duration impacts on genetic risk of depressive symptoms

Both long and short sleep durations are associated with an increased heritability of depression, study findings show.

17 Feb 2014

Invasive pneumococcal disease in Taiwan on the wane, but threats remain

The incidence of invasive pneumococcal disease in Taiwan has decreased significantly in recent years, study findings indicate.

17 Feb 2014

Blood pressure effects unclear in long-term stroke survivors

Long-term survivors of stroke whose blood pressure is at target levels have worse outcomes than those with slightly elevated levels, research suggests.

17 Feb 2014

New score ‘reliable and valid’ for neurogenic bladder dysfunction

The Neurogenic Bladder Symptom Score is both valid and reliable for assessing urinary dysfunction in people with acquired or congenital neurogenic bladder, according to a study published online in the Journal of Urology.

17 Feb 2014

Afatinib ‘first line’ for advanced mutation-positive lung cancer

Afatinib should be given as a first-line treatment for Asian patients with advanced, epidermal growth factor receptor mutation-positive, non-small-cell lung cancer, researchers recommend.

17 Feb 2014

Researchers conduct pioneering translational study on immediate antidepressant effect of DBS

A team of UCA researchers led by Professor Esther Berrocoso and in joint collaboration with the mental health research groups of the Centro de Investigación Biomédica en Red de Salud Mental have carried out a pioneering project in Spain.

17 Feb 2014

Study points to unique therapeutic approach for managing muscle-wasting conditions

New findings on why skeletal muscle stem cells stop dividing and renewing muscle mass during aging points up a unique therapeutic opportunity for managing muscle-wasting conditions in humans, says a new University of Colorado Boulder study.

17 Feb 2014

Subtle epigenetic change plays important role in correct segregation of chromosomes

Abnormal number of chromosomes is often associated with cancer development. In a new study published in the journal Nature Structural and Molecular Biology researchers at Karolinska Institutet in Sweden have shown that a subtle epigenetic change plays an important role in the correct segregation of chromosomes.

17 Feb 2014

Researchers identify new type of regulatory blood cells that can combat brain inflammation

Hyperactivity of our immune system can cause a state of chronic inflammation. If chronic, the inflammation will affect our body and result in disease. In the devastating disease multiple sclerosis, hyperactivity of immune cells called T-cells induce chronic inflammation and degeneration of the brain. Researchers at BRIC, the University of Copenhagen, have identified a new type of regulatory blood cells that can combat such hyperactive T-cells in blood from patients with multiple sclerosis. By stimulating the regulatory blood cells, the researchers significantly decreased the level of brain inflammation and disease in a biological model.

17 Feb 2014

New research points to potential target for treating triple negative breast cancer

New research from the University of Michigan Comprehensive Cancer Center and Georgia Regents University finds that a protein that fuels an inflammatory pathway does not turn off in breast cancer, resulting in an increase in cancer stem cells. This provides a potential target for treating triple negative breast cancer, the most aggressive form of the disease.

17 Feb 2014

More men contract chlamydia in Australia, finds new study

The largest Australian chlamydia study to date, led by the University of Melbourne, has found more men contract chlamydia than previously thought and most cases of infection are being missed.

17 Feb 2014

Sleep apnea may contribute to fatigue in people with multiple sclerosis

People with multiple sclerosis (MS) might assume that the fatigue they often feel just comes with the territory of their chronic neurological condition.

17 Feb 2014

Children exposed to cigarette smoke may have lesser response to asthma treatment

Children exposed to cigarette smoke at home have lower levels of an enzyme that helps them respond to asthma treatment, a study has found.

17 Feb 2014

Study shows vitamin D may provide some relief for patients with chronic hives

A study by researchers at the University of Nebraska Medical Center shows vitamin D as an add-on therapy could provide some relief for chronic hives, a condition with no cure and few treatment options.

17 Feb 2014

Study provides comprehensive analysis of the evolutionary relationships of influenza virus

A new study reconstructing the evolutionary tree of flu viruses challenges conventional wisdom and solves some of the mysteries surrounding flu outbreaks of historical significance.

17 Feb 2014

Researchers use new technique that can partially move tumors from inoperable locations in brain

One factor that makes glioblastoma cancers so difficult to treat is that malignant cells from the tumors spread throughout the brain by following nerve fibers and blood vessels to invade new locations.

17 Feb 2014

Scientists develop new paradigms for understanding how human brain works in health, disease

Understanding the human brain is one of the greatest challenges facing 21st century science. If we can rise to this challenge, we will gain profound insights into what makes us human, develop new treatments for brain diseases, and build revolutionary new computing technologies that will have far reaching effects, not only in neuroscience.

17 Feb 2014

Study shows increased brain reactivity may facilitate memorisation of dreams

Some people recall a dream every morning, whereas others rarely recall one. A team led by Perrine Ruby, an Inserm Research Fellow at the Lyon Neuroscience Research Center (Inserm/CNRS/Universit- Claude Bernard Lyon 1), has studied the brain activity of these two types of dreamers in order to understand the differences between them.

17 Feb 2014

Medical Research News

Polyplus-transfection grants research license to NIH for PEI-mediated transfection applications

Mini-sling partially successful for stress urinary incontinence

Sleep duration impacts on genetic risk of depressive symptoms

Invasive pneumococcal disease in Taiwan on the wane, but threats remain

Blood pressure effects unclear in long-term stroke survivors

New score ‘reliable and valid’ for neurogenic bladder dysfunction

Afatinib ‘first line’ for advanced mutation-positive lung cancer

Researchers conduct pioneering translational study on immediate antidepressant effect of DBS

Study points to unique therapeutic approach for managing muscle-wasting conditions

Subtle epigenetic change plays important role in correct segregation of chromosomes

Researchers identify new type of regulatory blood cells that can combat brain inflammation

New research points to potential target for treating triple negative breast cancer

More men contract chlamydia in Australia, finds new study

Sleep apnea may contribute to fatigue in people with multiple sclerosis

Children exposed to cigarette smoke may have lesser response to asthma treatment

Study shows vitamin D may provide some relief for patients with chronic hives

Study provides comprehensive analysis of the evolutionary relationships of influenza virus

Researchers use new technique that can partially move tumors from inoperable locations in brain

Scientists develop new paradigms for understanding how human brain works in health, disease

Study shows increased brain reactivity may facilitate memorisation of dreams

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