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Common mutations produce typical schizophrenia brain changes

Mutations in dopamine-related genes have a dose-response effect on prefrontal activation during emotional response inhibition in healthy adults, a study shows.

13 Feb 2014

Consistent mania monitoring during perinatal period warranted

Pregnant and postpartum women with bipolar disorder experience clinically severe symptoms, suggesting the need for continued monitoring of mania during this time, say researchers.

13 Feb 2014

Intravenous magnesium fails to improve stroke-related disability

Giving intravenous magnesium to stroke patients soon after the start of symptoms, in an attempt to protect brain cells deprived of oxygen, failed to improve stroke-related disability 3 months later, according to research presented at the American Stroke Association's International Stroke Conference 2014

13 Feb 2014

Researchers reveal how genome-editing tool works as 'guided missile' to correct errors in genetic code

Researchers from the Broad Institute and MIT have teamed up with colleagues from the University of Tokyo to form the first high definition picture of the Cas9 complex - a key part of the CRISPR-Cas system used by scientists as a genome-editing tool to silence genes and probe the biology of cells. Their findings, which are reported this week in Cell, are expected to help researchers refine and further engineer the tool to accelerate genomic research and bring the technology closer to use in the treatment of human genetic disease.

13 Feb 2014

Researchers discover promising new approach for leukemia treatment

A group of researchers at the Institute for Research in Immunology and Cancer of Universit- de Montr-al discovered a promising new approach to treating leukemia by disarming a gene that is responsible for tumor progression. That gene, known as Brg1 is a key regulator of leukemia stem cells that are the root cause of the disease, resistance to treatment and relapse.

13 Feb 2014

Moderate-intensity exercise reduces stroke risk in women

Women don't need to run marathons or do intense aerobics to reduce their stroke risk. Moderate-intensity exercise - such as brisk walking or playing tennis -- may do the trick, according to research presented at the American Stroke Association's International Stroke Conference 2014.

13 Feb 2014

New research identifies raised risk of self-harm among patients with certain physical illnesses

New research quantifying the risk of admission to hospital for self-harm has identified a raised risk of self-harm among groups of patients with certain physical illnesses. While it is known that psychiatric illnesses are associated with a greatly elevated risk of self-harm, a moderately elevated risk was seen with common physical illnesses such as diabetes, epilepsy and asthma.

13 Feb 2014

Heavy exposure to air pollution increases risk for developing hypertension during pregnancy

Breathing the air outside their homes may be just as toxic to pregnant women - if not more so - as breathing in cigarette smoke, increasing a mom-to-be's risk of developing deadly complications such as preeclampsia, according to findings from a new University of Florida study.

13 Feb 2014

Scientists take steps to identify genetic component to bipolar disorder

Scientists know there is a strong genetic component to bipolar disorder, but they have had an extremely difficult time identifying the genes that cause it. So, in an effort to better understand the illness's genetic causes, researchers at UCLA tried a new approach.

13 Feb 2014

Albert Einstein College professor receives AAAS 2013 Newcomb Cleveland Prize

A study describing the complete wiring diagram for the part of the nervous system that controls mating behavior in male roundworms was chosen as the most outstanding paper published in Science in the year June 2012 to May 2013.

13 Feb 2014

USC scientist wins AAAS Early Career Award for Public Engagement with Science

The American Association for the Advancement of Science (AAAS) has honored Mary Helen Immordino-Yang with the AAAS Early Career Award for Public Engagement with Science for her "sustained commitment and novel approach to integrating public engagement with science into her extensive research and scholarly activities and for using public interactions to inform her research."

13 Feb 2014

Congressmen to receive Edwin C. Whitehead award at Advocacy Awards Dinner

Reps. Frank Wolf (R-VA) and Chaka Fattah (D-PA) will receive the Edwin C. Whitehead Award for Medical Research Advocacy for their leadership and unwavering commitment to supporting policies that promote federal and private sector medical research and innovation.

13 Feb 2014

Researchers validate new method for calculating physical activity, sedentary behavior in obese people

Researchers at the University of South Carolina's Arnold School of Public Health have validated a new method for calculating physical activity, sedentary behavior, and the food energy requirements of Americans. The results suggest that as a nation, we spend more than 15 hours per day sleeping and sitting, and that obese men and women spend less than one minute per day in vigorous activity.

13 Feb 2014

Clot-busting tPA therapy for ischemic stroke patients can avoid lengthy, restrictive monitoring in ICU

A Johns Hopkins study of patients with ischemic stroke suggests that many of those who receive prompt hospital treatment with "clot-busting" tissue plasminogen activator (tPA) therapy can avoid lengthy, restrictive monitoring in an intensive care unit (ICU).

13 Feb 2014

Study uncovers how gut bacteria metabolize complex dietary carbohydrates in fruits, vegetables

We are all aware of the health benefits of dietary fiber. But what is dietary fiber and how do we metabolize it?

13 Feb 2014

Study disputes effectiveness of mortality as measure of quality of care provided to stroke patients

A new study disputes the effectiveness of mortality as a measure of the quality of care provided by hospitals to stroke patients. The paper - which was simultaneously presented today at the International Stroke Conference in San Diego and published in the journal Stroke - found that use of do-not-resuscitate orders differ widely between hospitals and that this variation can significantly skew a hospital's quality "ranking" based on mortality.

13 Feb 2014

Extracts from algae, rosemary and monk fruit could soon replace synthetic ingredients and food additives

Extracts from algae, rosemary and monk fruit could soon replace synthetic ingredients and food additives such as Blue No. 1, BHT and aspartame that label-conscious grocery shoppers are increasingly shunning.

13 Feb 2014

Odor-producing chemicals in earwax differ according to ethnic origin

Scientists from the Monell Center have used analytical organic chemistry to identify the presence of odor-producing chemical compounds in human earwax. Further, they found that the amounts of these compounds differ between individuals of East Asian origin and Caucasians.

13 Feb 2014

Parents and doctors must be aware and prepared to treat strokes in children

Parents and healthcare professionals must be aware that children can have strokes and be prepared to respond to symptoms, according to research presented at the American Stroke Association's International Stroke Conference 2014.

13 Feb 2014

CHOP develops unique laboratory test to characterize genes that encode HLA molecules

Immunogenetics experts at The Children's Hospital of Philadelphia (CHOP) have developed a unique laboratory test to characterize the genes that encode HLA molecules. The test relies on faster, more comprehensive gene sequencing technology to type human leukocyte antigens (HLAs)--complex, highly variable proteins on cell surfaces that are essential to immune function.

13 Feb 2014

Medical Research News

Common mutations produce typical schizophrenia brain changes

Consistent mania monitoring during perinatal period warranted

Intravenous magnesium fails to improve stroke-related disability

Researchers reveal how genome-editing tool works as 'guided missile' to correct errors in genetic code

Researchers discover promising new approach for leukemia treatment

Moderate-intensity exercise reduces stroke risk in women

New research identifies raised risk of self-harm among patients with certain physical illnesses

Heavy exposure to air pollution increases risk for developing hypertension during pregnancy

Scientists take steps to identify genetic component to bipolar disorder

Albert Einstein College professor receives AAAS 2013 Newcomb Cleveland Prize

USC scientist wins AAAS Early Career Award for Public Engagement with Science

Congressmen to receive Edwin C. Whitehead award at Advocacy Awards Dinner

Researchers validate new method for calculating physical activity, sedentary behavior in obese people

Clot-busting tPA therapy for ischemic stroke patients can avoid lengthy, restrictive monitoring in ICU

Study uncovers how gut bacteria metabolize complex dietary carbohydrates in fruits, vegetables

Study disputes effectiveness of mortality as measure of quality of care provided to stroke patients

Extracts from algae, rosemary and monk fruit could soon replace synthetic ingredients and food additives

Odor-producing chemicals in earwax differ according to ethnic origin

Parents and doctors must be aware and prepared to treat strokes in children

CHOP develops unique laboratory test to characterize genes that encode HLA molecules

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