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Environmental factors and genes play key role in cancer development

A new editorial was published in Oncotarget, Volume 16, on March 10, 2025, titled "EXPOSOMES and GENES: The duo influencing CANCER initiation and progression."

11 Mar 2025

Arthritis and COPD together raise mortality risk

People with chronic obstructive pulmonary disease (COPD) and arthritis have a higher risk of death than people with arthritis who do not have COPD, according to a new study.

11 Mar 2025

Microplastics found to promote antibiotic resistance in bacteria

Microplastics-tiny shards of plastic debris-are all over the planet. They have made their way up food chains, accumulated in oceans, clustered in clouds and on mountains, and been found inside our bodies at alarming rates.

11 Mar 2025

Machine learning models fall short in predicting in-hospital mortality

It would be greatly beneficial to physicians trying to save lives in intensive care units if they could be alerted when a patient's condition rapidly deteriorates or shows vitals in highly abnormal ranges.

11 Mar 2025

Gender gaps in peripheral vascular disease impact diagnosis and treatment

The disparities between men and women in prevalence, risk factors and symptoms of peripheral vascular disease (PVD) have a profound impact on prevention, diagnosis, treatment and outcomes for women, according to a new American Heart Association scientific statement published today in the Association's flagship, peer-reviewed journal Circulation.

11 Mar 2025

A safer and more affordable polio vaccine could soon be a reality

A more affordable, lower-risk polio vaccine is on the horizon, research led by the University of Leeds has found.

11 Mar 2025

Nwd1 gene linked to liver dysfunction in metabolic disease

Metabolic dysfunction-associated steatohepatitis (MASH) is a liver disease that progresses without symptoms and is associated with significant global public health concerns.

11 Mar 2025

Study explores impact of pandemics on birth rates in Switzerland

Researchers at UZH have studied the impact of pandemics on the birth rate in Switzerland for the first time.

11 Mar 2025

PlasticHeal project sheds light on hidden health effects of nanoplastics

Microplastics and nanoplastics, two of the smallest and most invisible forms of plastic pollution, may pose risks to human health.

11 Mar 2025

Exercise intervention reduces fall risk in elderly women on multiple medications

An exercise intervention aimed at elderly women was successful at reducing falls, especially among those with polypharmacy, a new study from the University of Eastern Finland and Kuopio University Hospital shows.

11 Mar 2025

Self-sampling could reduce disparities in cervical screening

New research from University of Manchester experts suggests that introducing a UK-wide self-sampling program alongside existing ‘smear tests’ could help to remove most of the current barriers to cervical screening.

11 Mar 2025

Seafood consumption linked to prosocial behavior in children

Children who consumed the least amounts of seafood at 7-years-old were likely to be less 'prosocial' at ages 7 and 9 years than those who regularly consumed seafood, according to a new study.

11 Mar 2025

Integrated anti-aging strategy could reduce neurodegeneration

Aging significantly impacts neurodegeneration, increasing risks for diseases like Alzheimer's. Research focuses on therapies to enhance cognitive function.

11 Mar 2025

Switching from butter to plant-based oils linked to lower mortality risk

Researchers compare how the consumption of butter or plant-based oil impacts total and cause-specific mortality.

11 Mar 2025

Maternal cannabis use disorder linked to increased risk of child behavioral disorders

Researchers determine how maternal cannabis use disorder during and after pregnancy impacts the child’s behavior.

11 Mar 2025

Novel regulators in digestive tract disease progression and treatment

This new article published in Genes & Diseases highlights the critical role of tRNA-derived small RNAs (tsRNAs) in digestive tract diseases, positioning these molecules as potential biomarkers for diagnosis, prognosis, and targeted therapies. The comprehensive review explores the biogenesis, classification, and biological functions of tsRNAs, shedding light on their influence over cellular processes such as translation regulation, epigenetic modification, and protein interactions.

11 Mar 2025

Study reveals the role of transcription factors as therapeutic gateways in MAFLD

Metabolic dysfunction-associated fatty liver disease (MAFLD) has become a growing global health concern, affecting millions worldwide. This complex liver disorder ranges from simple steatosis to more severe forms, including metabolic dysfunction-associated steatohepatitis (MASH), which may progress to fibrosis, cirrhosis, and even liver cancer.

11 Mar 2025

Study investigates genetic mutations linked to occupational exposures

Occupational and environmental exposures can put specific groups of people at higher risk of cancer, including firefighters. A new study by investigators at Mass General Brigham examines a cancer rarely studied in firefighters: gliomas-a type of tumor that forms in the brain or spinal cord.

11 Mar 2025

Decoding programmed cell death in breast cancer

This review highlights the critical role of ubiquitin-specific proteases (USPs) in regulating programmed cell death (PCD) in breast cancer (BC). As the most prevalent malignant tumor among women, BC remains a significant global health challenge.

11 Mar 2025

Study highlights the role of ELF4 as a key transcription factor in development, immunity, and oncology

ELF4, a transcription factor belonging to the ETS family, has emerged as a pivotal regulator in cell differentiation, immune system function, and cancer progression. This newly published review underscores its molecular complexity and clinical significance, shedding light on its dual role in tumor suppression and oncogenesis.

11 Mar 2025