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Cholinergic degeneration marks gait speed in Parkinson’s patients

Gait speed is preserved in patients with Parkinson’s disease who have isolated dopaminergic denervation, but reduced in those with comorbid cholinergic denervation, research shows.

10 Oct 2013

Computer training for Parkinson’s patients improves driving performance marker

A self-administered, nonpharmalogic intervention significantly improves the useful field of view (UFOV) of patients with Parkinson’s disease, shows a randomized trial.

10 Oct 2013

Nonmotor signs aid Parkinson’s diagnosis

Physicians should account for nonmotor symptoms when diagnosing Parkinson’s disease, researchers believe.

10 Oct 2013

Constellation Pharmaceuticals awarded grant to facilitate study of epigenetic control of inflammation

Constellation Pharmaceuticals, Inc., a clinical-stage biopharmaceutical company in the field of epigenetics, today announced that it has been awarded a research grant in collaboration with the University of Pittsburgh School of Medicine from the Cystic Fibrosis Foundation to explore the potential use of BET bromodomain inhibitors for the control of inflammation in cystic fibrosis.

10 Oct 2013

New research shows high levels of aluminium in infant formulas

New research from Keele University shows that infant formulas are still heavily contaminated with aluminium.

10 Oct 2013

Drugs often fail to bring acromegaly under control in routine clinical practice

Over a quarter of UK patients treated for growth hormone-producing tumours do not achieve 'safe' growth hormone levels, according to a 30 year UK multi-centre study of clinical management of the rare disease acromegaly. The findings by the Society for Endocrinology UK Acromegaly Register, published in the November issue of Clinical Endocrinology, show that drugs to control acromegaly often fail to bring the disease completely under control in routine clinical practice.

10 Oct 2013

Heptares' StaR platform offers breakthrough solution to challenge associated with antibodies therapeutics

Heptares Therapeutics, the leading GPCR structure-guided drug discovery and development company, achieved the first research milestone in its antibody therapeutics alliance with MorphoSys AG (FSE: MOR; Prime Standard Segment, TecDAX), announced in February 2013.

10 Oct 2013

Running a marathon can damage heart muscle for unfit runners

Investigators who studied a group of recreational marathon runners have established that strenuous exercise such as running a marathon can damage the heart muscle. Although they found the effect is temporary and reversible, they warn that these effects are more widespread in less fit distance runners and that recreational distance runners should prepare properly before marathons.

10 Oct 2013

Charles J. Sherr to receive Prize for Scientific Excellence in Medicine

Charles J. Sherr, M.D., Ph.D., chair of the St. Jude Children's Research Hospital Department of Tumor Cell Biology and a Howard Hughes Medical Institute Investigator, has been selected to receive the 2013 Prize for Scientific Excellence in Medicine by the American-Italian Cancer Foundation.

10 Oct 2013

Recovery sleep over weekend may not reverse all effects of sleep lost during workweek

In many modern societies, adults often sacrifice sleep during the workweek to make time for other demands, then snooze longer on the weekends to recoup that lost sleep. Research has shown that even a few days of lost sleep can have adverse effects, including increased daytime sleepiness, worsened daytime performance, an increase in molecules that are a sign of inflammation in the body, and impaired blood sugar regulation.

10 Oct 2013

Transcendental Meditation technique has large effect on reducing trait anxiety, shows analysis

A new meta-analysis published today in the Journal of Alternative and Complementary Medicine (2013;19(10):1-12)1 found the Transcendental Meditation- technique (TM) has a large effect on reducing trait anxiety for people with high anxiety.

10 Oct 2013

Intravenous feeding can cause liver damage, say researchers

Researchers know that feeding some patients intravenously can save their lives - but also can cause liver damage. Now scientists at the University of Colorado and Children's Hospital Colorado have figured out the likely culprit, one of the ingredients in intravenous food, behind the liver problems.

10 Oct 2013

BMC finds patients with high degree of skills, confidence less likely to have hospital readmissions

A study by physicians at Boston Medical Center (BMC), has found that patients with a high degree of activation (possessing the knowledge, skills, confidence and inclination to assume responsibility for managing one's health and health-care needs) were less likely to be readmitted to the hospital within 30 days of discharge than those with a low level of activation.

10 Oct 2013

Chemists discover mystery of how organic crystals form

New York University chemists have discovered crystal growth complexities, which at first glance appeared to confound 50 years of theory and deepened the mystery of how organic crystals form. But, appearances can be deceiving.

10 Oct 2013

Thermo Scientific launches picoSpin 80 portable NMR spectrometer for benchtop operation

Academic and industrial laboratories can now easily collect routine high-resolution nuclear magnetic resonance (NMR) data on molecules in solution using the Thermo Scientific picoSpin 80, a portable, competitively-priced NMR spectrometer built for benchtop operation.

10 Oct 2013

Beta-blocker therapy controls heart rate, improves cardiovascular performance in septic shock patients

Andrea Morelli, M.D., of the University of Rome, Italy, and colleagues conducted a study to investigate the effect of the short-acting beta-blocker esmolol on the heart rate of patients with severe septic shock and high risk of death.

10 Oct 2013

Gene mutation offers clues to development of diverse neurological disorders

A research team, headed by Theodore Friedmann, MD, professor of pediatrics at the University of California, San Diego School of Medicine, says a gene mutation that causes a rare but devastating neurological disorder known as Lesch-Nyhan syndrome appears to offer clues to the developmental and neuronal defects found in other, diverse neurological disorders like Alzheimer's, Parkinson's and Huntington's diseases.

10 Oct 2013

Halloween parties can heighten danger for kids with food allergies

The scary reality is that food allergies are becoming more and more common in the United States. In the past 10 years there has been an 18 percent increase in children with food allergies.

10 Oct 2013

Survivors of critical illness experience significant skeletal muscle weakness

Zudin A. Puthucheary, M.R.C.P., of University College London, England, and colleagues conducted a study to characterize and evaluate the time course and pathophysiology of acute muscle loss in critical illness.

10 Oct 2013

Theraclion unveils very positive initial clinical results in treatment of thyroid nodules

Theraclion, a company specializing in advanced medical equipment for echotherapy (or ultrasound therapy), has unveiled very positive initial clinical results in the treatment of thyroid nodules. These findings demonstrate the effectiveness of its Echopulse device in the treatment of this condition.

10 Oct 2013

Medical Research News

Cholinergic degeneration marks gait speed in Parkinson’s patients

Computer training for Parkinson’s patients improves driving performance marker

Nonmotor signs aid Parkinson’s diagnosis

Constellation Pharmaceuticals awarded grant to facilitate study of epigenetic control of inflammation

New research shows high levels of aluminium in infant formulas

Drugs often fail to bring acromegaly under control in routine clinical practice

Heptares' StaR platform offers breakthrough solution to challenge associated with antibodies therapeutics

Running a marathon can damage heart muscle for unfit runners

Charles J. Sherr to receive Prize for Scientific Excellence in Medicine

Recovery sleep over weekend may not reverse all effects of sleep lost during workweek

Transcendental Meditation technique has large effect on reducing trait anxiety, shows analysis

Intravenous feeding can cause liver damage, say researchers

BMC finds patients with high degree of skills, confidence less likely to have hospital readmissions

Chemists discover mystery of how organic crystals form

Thermo Scientific launches picoSpin 80 portable NMR spectrometer for benchtop operation

Beta-blocker therapy controls heart rate, improves cardiovascular performance in septic shock patients

Gene mutation offers clues to development of diverse neurological disorders

Halloween parties can heighten danger for kids with food allergies

Survivors of critical illness experience significant skeletal muscle weakness

Theraclion unveils very positive initial clinical results in treatment of thyroid nodules

Precision in every drop: Inside Hamilton’s syringe technology

Exploring the Future of Neuroscience Drug Discovery

Genomic conservation in Thailand's mangroves

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