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Scientist receives € 2M Consolidator Grant for creation of new anti-tumour drugs

scar Fern-ndez-Capetillo's research group has developed compounds that only a few weeks ago were licensed by the Spanish National Cancer Research Centre (CNIO) to a pharmaceutical company for the creation of new anti-tumour drugs.

16 Jan 2014

Research highlights innovative, complex fermented beverages of northern Europe in the Bronze, Iron Ages

A blazing fire was not the only thing to keep Bronze and Iron Age Scandinavians warm through long cold winters. From northwest Denmark, circa 1500-1300 BC, to the Swedish island of Gotland as late as the first century AD, Nordic peoples were imbibing an alcoholic "grog" or extreme hybrid beverage rich in local ingredients, including honey, bog cranberry, lingonberry, bog myrtle, yarrow, juniper, birch tree resin, and cereals including wheat, barley and/or rye —and sometimes, grape wine imported from southern or central Europe.

16 Jan 2014

CU researcher awarded NIH grant to study benefit of allopurino drug in lowering uric acid levels

Kidney disease poses one of the greatest burdens for people living with type 1 diabetes. A study newly awarded by the National Institutes of Health will look at whether lowering uric acid levels can prevent people with type 1 diabetes from needing hemodialysis or kidney transplant.

15 Jan 2014

Research shows how coevolution between humans and bacteria can affect gastric cancer risk

Research carried out in two distinct communities in Colombia illustrates how coevolution between humans and bacteria can affect a person's risk of disease. Working with colleagues in Columbia and the U.S., Scott Williams, PhD, a professor of genetics at the Geisel School of Medicine at Dartmouth, and his graduate student Nuri Kodaman discovered that the risk of developing gastric cancer depends heavily on both the ancestry of the person and the ancestry of Helicobacter pylori with which that person is infected.

15 Jan 2014

Study suggests effective way to counter influenza infections

McGill researchers, led by Dr. Maya Saleh of the Department of Medicine, have identified an enzyme, cIAP2 that helps the lungs protect themselves from the flu by giving them the ability to resist tissue damage. "It's a discovery that offers exciting new avenues for controlling influenza, since until now attempts to target the virus itself have proven challenging, especially in the face of emerging new strains of the virus," says Saleh, who is also a researcher at the Research Institute of the McGill University Health Centre.

15 Jan 2014

New study examines factors that may lead to end stage renal disease

About 33 percent of people with type 2 diabetes suffer kidney damage that progresses to end stage renal disease, at which point they require either dialysis or kidney transplantation. Scientists have thought that this kidney disease is driven by damage to the glomeruli, blood vessels in the kidney, which spill the protein albumin into the urine. Current treatments targeting the resulting "albuminuria" do not prevent kidney failure.

15 Jan 2014

International study develops refined method to identify individuals at risk for certain inherited cancer

An international study has developed a refined method to identify people at risk for certain inherited cancer as a result of Lynch syndrome.

15 Jan 2014

Spinal cord injury patients could benefit from careful assessment for sleep apnea

A new study suggests that patients with spinal cord injuries could benefit from careful assessment for sleep apnea.

15 Jan 2014

PGC-1α protein found in muscle may contributes to the development of type 2 diabetes later in life

A Montr-al research team led by Jennifer Estall at the IRCM discovered that a protein found in muscle tissue may contribute to the development of type 2 diabetes later in life. The study's results, published in today's printed edition of the scientific journal American Journal of Physiology - Endocrinology and Metabolism, indicate that the protein could be a promising early predictor of increased diabetes risk.

15 Jan 2014

Researchers explore new strategy to defeat drug-resistant strains of malaria

Malaria is one of the most deadly infectious diseases in the world today, claiming the lives of over half a million people every year, and the recent emergence of parasites resistant to current treatments threatens to undermine efforts to control the disease. Researchers are now onto a new strategy to defeat drug-resistant strains of the parasite. Their report appears in the journal ACS Chemical Biology.

15 Jan 2014

Researchers report three-fold increase in use of minimally invasive surgery for pancreatic disease

Researchers at University of California, San Diego School of Medicine report a three-fold increase in the use of minimally invasive surgery across the nation for patients with pancreatic disease. Although adaptation of MIS for this difficult-to-reach gland is recent, the growing trend points to improved patient outcomes, such as reduced bleeding and infections. Now published online, the paper will appear in the March print edition of JAMA Surgery.

15 Jan 2014

Call for long follow-up after CIN3 treatment

Researchers from Sweden say that women who have been treated for cervical precancer should receive lifelong follow-up, after finding that their risk for dying from vaginal or cervical cancer markedly increases after the age of 60 years.

15 Jan 2014

More evidence for glutamate dysregulation in schizophrenia

Levels of glutamine, but not glutamate, are elevated in the dorsal anterior cingulate of patients with established schizophrenia, say researchers.

15 Jan 2014

Emotion regulation deficits characterize bipolar and MDD patients

Patients with bipolar disorder and major depressive disorder have increased use of maladaptive and decreased use of adaptive emotion regulation strategies, researchers report.

15 Jan 2014

Research findings provide insights into risks associated with isolated mild hyperglycemia

Despite having mild hyperglycemia for approximately 50 years, patients with a mutation in the gene encoding the enzyme glucokinase had a low prevalence of clinically significant vascular complications, findings that provide insights into the risks associated with isolated mild hyperglycemia, according to a study in the January 15 issue of JAMA.

15 Jan 2014

New stem cell study explains how breast cancer spreads

Breast cancer stem cells exist in two different states and each state plays a role in how cancer spreads, according to an international collaboration of researchers. Their finding sheds new light on the process that makes cancer a deadly disease.

15 Jan 2014

Study reveals high prevalence of TB infection among young children

A small study by investigators from the Johns Hopkins Children's Center and Byramjee Jeejeebhoy Government Medical College in India reveals high prevalence of tuberculosis infection among young children, troubling rates of disseminated disease and alarming patterns of drug resistance.

15 Jan 2014

Research identifies new way for slow release drugs

Reservoirs of pharmaceuticals could be manufactured to bind specifically to infected tissue such as cancer cells for slow, concentrated delivery of drug treatments, according to new research published in ACS Macro Letters.

15 Jan 2014

Cognigram can detect early signs of MCI and Alzheimer’s disease

For patients over the age of 50, a routine physical exam at the doctor’s office typically covers a wide spectrum of medical biomarkers with one glaring exception, cognitive health. Unless there have been unusual mental changes or challenges in their daily life, tests of a patient’s attention, memory or brain processing speed is usually not part of a check-up.

15 Jan 2014

BMH-21 chemical compound has ability to shut down a common cancer process

Johns Hopkins scientists say a previously known but little studied chemical compound targets and shuts down a common cancer process. In studies of laboratory-grown human tumor cell lines, the drug disrupted tumor cell division and prevented growth of advanced cancer cells.

15 Jan 2014

Medical Research News

Scientist receives € 2M Consolidator Grant for creation of new anti-tumour drugs

Research highlights innovative, complex fermented beverages of northern Europe in the Bronze, Iron Ages

CU researcher awarded NIH grant to study benefit of allopurino drug in lowering uric acid levels

Research shows how coevolution between humans and bacteria can affect gastric cancer risk

Study suggests effective way to counter influenza infections

New study examines factors that may lead to end stage renal disease

International study develops refined method to identify individuals at risk for certain inherited cancer

Spinal cord injury patients could benefit from careful assessment for sleep apnea

PGC-1α protein found in muscle may contributes to the development of type 2 diabetes later in life

Researchers explore new strategy to defeat drug-resistant strains of malaria

Researchers report three-fold increase in use of minimally invasive surgery for pancreatic disease

Call for long follow-up after CIN3 treatment

More evidence for glutamate dysregulation in schizophrenia

Emotion regulation deficits characterize bipolar and MDD patients

Research findings provide insights into risks associated with isolated mild hyperglycemia

New stem cell study explains how breast cancer spreads

Study reveals high prevalence of TB infection among young children

Research identifies new way for slow release drugs

Cognigram can detect early signs of MCI and Alzheimer’s disease

BMH-21 chemical compound has ability to shut down a common cancer process

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