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New study may pave way for more effective treatment for deadly childhood cancer

A new study by Canadian researchers may pave the way for more effective treatment of an aggressive and deadly type of brain tumour, known as ETMR/ETANTR. The tumour, which is seen only in children under four, is almost always fatal, despite aggressive treatment. The study proposes a new model for how this brain tumour develops and suggests possible targets to investigate for novel therapies.

12 Dec 2013

Study resolves 50-year 'chlamydial anomaly' using novel method

Researchers studying Chlamydia trachomatis bacteria, which cause the sexually transmitted infection chlamydia as well as infectious blindness, have confirmed that the bacteria contain-and, in fact, cannot function without-the common molecule peptidoglycan, a structural component found in the cell wall of many bacteria. This finding puts an end to years of uncertainty about whether Chlamydia bacteria, like almost all bacterial species, rely on peptidoglycan to reproduce and to maintain their shape and structure. In addition, the novel method the investigators used may be adapted to further examine the molecule's role in the structure and function of other bacteria.

12 Dec 2013

Scientists use new method to map response of every salmonella gene to conditions in human body

Scientists have used a new method to map the response of every salmonella gene to conditions in the human body, providing new insight into how the bacteria triggers infection.

12 Dec 2013

Researchers identify variations in gene that doubles risk of developing Alzheimer's disease

A team led by researchers at Washington University School of Medicine in St. Louis has identified variations in a gene that doubles a person's risk of developing Alzheimer's disease later in life.

12 Dec 2013

MedImmune, Johns Hopkins University enter into $6.5M research collaboration

MedImmune, AstraZeneca’s global biologics research and development arm, and The Johns Hopkins University today announced they have entered into a five-year, $6.5 million research collaboration.

12 Dec 2013

Study: Girls in single-sex schools feel more pressure to act like "typical girls"

Newspaper headlines worldwide tout the benefits of single-sex schools: Girls 75% more likely to take math if they go to a single-sex private school, Will boys learn better if girls aren't allowed? Single-sex education is best for girls in stereotypically male subjects.

12 Dec 2013

Two tumor-suppressing genes could play vital role in controlling obesity, cancer, diabetes

The function of two tumor-suppressing genes could play a vital role in helping to control obesity and other diseases such as diabetes, heart disease and cancer, according to researchers in Temple University's Sbarro Institute for Cancer Research and Molecular Medicine.

12 Dec 2013

Study finds link between consumption of foods from restaurants and obesity risk in African Americans

Americans are increasingly eating more of their meals prepared away from home, and this is particularly true among African Americans, who also have higher rates of obesity than other Americans. Young adults tend to eat out more often at fast-food restaurants and these establishments are more often found in minority neighborhoods.

12 Dec 2013

NIH data-sharing may advance genetic and translational research, therapeutic target discovery

For the first time, large-scale information on the biochemical makeup of small interfering RNA (siRNA) molecules is available publicly. These molecules are used in research to help scientists better understand how genes function in disease.

12 Dec 2013

Dietary amino acids improve sleep disturbances caused by brain injuries in animals

Scientists who fed a cocktail of key amino acids to mice improved sleep disturbances caused by brain injuries in the animals. These new findings suggest a potential dietary treatment for millions of people affected by traumatic brain injury (TBI)—a condition that is currently untreatable.

12 Dec 2013

Rice U. develops temperature-sensitive gelling scaffolds to regenerate craniofacial bone

Rice University bioengineers have developed a hydrogel scaffold for craniofacial bone tissue regeneration that starts as a liquid, solidifies into a gel in the body and liquefies again for removal.

12 Dec 2013

Study finds that people with COPD twice likely to develop mild cognitive impairment, memory loss

A recent Mayo Clinic study found that people with chronic obstructive pulmonary disease (COPD) are about twice as likely to develop mild cognitive impairment (MCI) -- and chances are that it will include memory loss. The study was recently published in Mayo Clinic Proceedings.

12 Dec 2013

U.S. Marines investigate association between traumatic brain injury and risk of PTSD

In a novel study of U.S. Marines investigating the association between traumatic brain injury (TBI) and the risk of post-traumatic stress disorder (PTSD) over time, a team of scientists led by researchers from the Veterans Affairs San Diego Healthcare System and University of California, San Diego School of Medicine report that TBIs suffered during active-duty deployment to Iraq and Afghanistan were the greatest predictor for subsequent PTSD, but found pre-deployment PTSD symptoms and high combat intensity were also significant factors.

12 Dec 2013

Diabetes researcher awarded 2013 JDRF Australia Lifetime Research Achievement Award

Diabetes researcher Professor Len Harrison has been awarded the 2013 JDRF Australia Lifetime Research Achievement Award for his research to improve treatments for people with diabetes, or prevent its development.

11 Dec 2013

New drug combination therapy effective for patients with HER2-positive breast cancer

Combining the chemotherapy drugs docetaxel and carboplatin with the HER2-targeted therapy trastuzumab was identified to be an ideal postsurgery treatment option for patients with HER2-positive breast cancer, regardless of tumor size and whether or not disease has spread to the lymph nodes, according to results from the BETH study presented here at the 2013 San Antonio Breast Cancer Symposium, held Dec. 10-14.

11 Dec 2013

Researchers find decreased energy metabolism in heart cells as significant independent risk factor

Johns Hopkins researchers have identified a new way to predict which heart failure patients are likely to see their condition get worse and which ones have a better prognosis. Their study is one of the first to show that energy metabolism within the heart, measured using a noninvasive magnetic resonance imaging test, is a significant predictor of clinical outcomes, independent of a patient's symptoms or the strength of the heart's ability to pump blood, known as the ejection fraction.

11 Dec 2013

Medical Research News

New study may pave way for more effective treatment for deadly childhood cancer

Study resolves 50-year 'chlamydial anomaly' using novel method

Scientists use new method to map response of every salmonella gene to conditions in human body

Researchers identify variations in gene that doubles risk of developing Alzheimer's disease

MedImmune, Johns Hopkins University enter into $6.5M research collaboration

Study: Girls in single-sex schools feel more pressure to act like "typical girls"

Two tumor-suppressing genes could play vital role in controlling obesity, cancer, diabetes

Study finds link between consumption of foods from restaurants and obesity risk in African Americans

NIH data-sharing may advance genetic and translational research, therapeutic target discovery

Dietary amino acids improve sleep disturbances caused by brain injuries in animals

Rice U. develops temperature-sensitive gelling scaffolds to regenerate craniofacial bone

Study finds that people with COPD twice likely to develop mild cognitive impairment, memory loss

U.S. Marines investigate association between traumatic brain injury and risk of PTSD

Diabetes researcher awarded 2013 JDRF Australia Lifetime Research Achievement Award

New drug combination therapy effective for patients with HER2-positive breast cancer

Researchers find decreased energy metabolism in heart cells as significant independent risk factor

Low sodium levels linked to poor targeted therapy outcomes in RCC

Early tumor shrinkage predicts targeted therapy efficacy in RCC

Shared genetic risk for bipolar and alcohol use disorders

Early antibiotic use linked to asthma, not atopy

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