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First clinical study for development of SGX203 to treat pediatric Crohn's disease

Soligenix, Inc. (Soligenix or the Company), a clinical stage biopharmaceutical company focused on developing products to treat inflammatory diseases and biodefense countermeasures where there remains an unmet medical need, announced today that it has enrolled and treated all patients in the Phase 1 Study BDP-PCD-01; the first clinical study for development of SGX203 (oral beclomethasone 17,21-dipropionate or oral BDP) for the treatment of pediatric Crohn's disease.

1 Jul 2013

Nano and laser technology packed into small device tests antibiotic treatment in minutes

Researchers at EPFL have built a matchbox-sized device that can test for the presence of bacteria in a couple of minutes, instead of up to several weeks. A nano-lever vibrates in the presence of bacterial activity, while a laser reads the vibration and translates it into an electrical signal that can be easily read-the absence of a signal signifies the absence of bacteria.

1 Jul 2013

Researchers discover an important mechanism that regulates proteasome activity

Dysfunction of the ubiquitin-proteasome system (UPS) has been detected in many neurodegenerative diseases, such as Alzheimer's and Parkinson's diseases, and certain types of cancer. Such dysfunction is also believed to be related to some degenerative muscle diseases. Researchers at the University of Helsinki, Finland, have now discovered an important mechanism that regulates proteasome activity.

1 Jul 2013

Researchers find fear can increase or decrease ability to discriminate among sounds depending on context

Anyone who's ever heard a Beethoven sonata or a Beatles song knows how powerfully sound can affect our emotions. But it can work the other way as well - our emotions can actually affect how we hear and process sound.

1 Jul 2013

Protein in liver plays a crucial role in mice's pregnancy and human menstrual cycle

A protein first shown to function in the liver plays a crucial role in pregnancy in mice and has a key role in the human menstrual cycle, according to researchers at the University of Montreal. Mice that were genetically engineered not to produce the liver receptor homolog-1 (Lrh-1) molecule were unable to create the uterine conditions necessary for establishing and sustaining pregnancy, resulting in the formation of defective placentas.

1 Jul 2013

Scientists identify neuronal circuits in spinal cord control limb alternation during walking

Scientists at Karolinska Institutet in Sweden have identified the neuronal circuits in the spinal cord of mice that control the ability to produce the alternating movements of the legs during walking.

1 Jul 2013

Tiny RNA molecules work as powerful regulators of immune response in mammals

A team led by scientists at The Scripps Research Institute (TSRI) has identified a family of tiny RNA molecules that work as powerful regulators of the immune response in mammals. Mice who lack these RNA molecules lose their normal infection-fighting ability, whereas mice that overproduce them develop a fatal autoimmune syndrome.

1 Jul 2013

Study: Tobacco control measures to prevent some 7.4 million premature deaths by 2050

Tobacco control measures put in place in 41 countries between 2007 and 2010 will prevent some 7.4 million premature deaths by 2050, according to a study published in the Bulletin of the World Health Organization today.

1 Jul 2013

Study indicates "statin-intolerant" patients can reduce cholesterol by visiting lipid clinic treatment

Up to 15 percent of patients who take cholesterol-lowering statin medications experience muscle pain or other side effects, and many patients simply stop taking the drugs.

30 Jun 2013

Biomolecular interactions of nanoparticles can improve drug development, optical sensors and more

In chemical reactions, left and right can make a big difference. A "left-handed" molecule of a particular chemical composition could be an effective drug, while its mirror-image "right-handed" counterpart could be completely inactive.

30 Jun 2013

Synthetic biology technology could lead to new antibiotics, modified protein-generators

Synthetic biology researchers at Northwestern University, working with partners at Harvard Medical School, have for the first time synthesized ribosomes -- cell structures responsible for generating all proteins and enzymes in our bodies -- from scratch in a test tube.

30 Jun 2013

Biomarker indicates which women are at risk for breast cancer recurrence after tamoxifen

A biomarker reflecting expression levels of two genes in tumor tissue may be able to predict which women treated for estrogen-receptor (ER)-positive breast cancer should receive a second estrogen-blocking medication after completing tamoxifen treatment.

30 Jun 2013

Physical activity and low calorie food may reduce risk of aggressive prostate cancer

Researchers at UCLA's Jonsson Comprehensive Cancer Center (JCCC) have published the first study on adherence to eight World Cancer Research Fund (WCRF) lifestyle recommendations and aggressive prostate cancer that shows a significantly decreased risk of highly aggressive prostate cancer associated with closer adherence to the recommendations.

30 Jun 2013

Molecular protein folding process may help medical researchers understand and treat diseases

Scientists using sophisticated imaging techniques have observed a molecular protein folding process that may help medical researchers understand and treat diseases such as Alzheimer's, Lou Gehrig's and cancer.

30 Jun 2013

Pre-deployment insomnia symptoms associated with major mental disorders

A new study from the Perelman School of Medicine at the University of Pennsylvania and the Naval Health Research Center has shown Military service members who have trouble sleeping prior to deployments may be at greater risk of developing posttraumatic stress disorder (PTSD), depression and anxiety once they return home.

30 Jun 2013

Researchers develop new drug delivery systems to treat cancer by blocking signaling receptor

A cardiac hormone signaling receptor abundantly expressed both in inflamed tissues and cancers appears to recruit stem cells that form the blood vessels needed to feed tumor growth, reports a new study by scientists at the University of South Florida Nanomedicine Research Center.

30 Jun 2013

Transplanted bone marrow stem cells in patients with type 2 diabetes reduce insulin use

A study carried out in India examining the safety and efficacy of self-donated (autologous), transplanted bone marrow stem cells in patients with type 2 diabetes (TD2M), has found that patients receiving the transplants, when compared to a control group of TD2M patients who did not receive transplantation, required less insulin post-transplantation.

30 Jun 2013

Medical Research News

First clinical study for development of SGX203 to treat pediatric Crohn's disease

Nano and laser technology packed into small device tests antibiotic treatment in minutes

Researchers discover an important mechanism that regulates proteasome activity

Researchers find fear can increase or decrease ability to discriminate among sounds depending on context

Protein in liver plays a crucial role in mice's pregnancy and human menstrual cycle

Scientists identify neuronal circuits in spinal cord control limb alternation during walking

Tiny RNA molecules work as powerful regulators of immune response in mammals

Study: Tobacco control measures to prevent some 7.4 million premature deaths by 2050

Study indicates "statin-intolerant" patients can reduce cholesterol by visiting lipid clinic treatment

Biomolecular interactions of nanoparticles can improve drug development, optical sensors and more

Synthetic biology technology could lead to new antibiotics, modified protein-generators

Biomarker indicates which women are at risk for breast cancer recurrence after tamoxifen

Physical activity and low calorie food may reduce risk of aggressive prostate cancer

Molecular protein folding process may help medical researchers understand and treat diseases

Pre-deployment insomnia symptoms associated with major mental disorders

Researchers develop new drug delivery systems to treat cancer by blocking signaling receptor

Transplanted bone marrow stem cells in patients with type 2 diabetes reduce insulin use

Chronic sleep restriction among adults with late bedtimes may be associated with weight gain

New procedure to treat acid reflux can prevent chronic rejection in lung transplant patients

Test-based approach of WHO unsuitable for regions where lot of malaria occurs: Research

Clue's CEO Rhiannon White on the Future of Femtech and PCOS

Freezing Point Osmometry in Life Science Applications

Precision in every drop: Inside Hamilton’s syringe technology

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