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Study: Assessment of risk in patients who commit suicide and homicide is often poor

The assessment of risk in patients who go on to die by suicide or commit homicide is often poor, a new study has found. A report by The University of Manchester's National Confidential Inquiry (NCI) into Suicide and Homicide by People with Mental Illness out today has raised concerns about the way that risk is assessed and led to criticism of the tick-box approach to clinical practice.

26 Jun 2013

Findings suggest BRAF-mutant colon tumor cells may be less sensitive to the effect of aspirin

In 2 large studies, the association between aspirin use and risk of colorectal cancer was affected by mutation of the gene BRAF, with regular aspirin use associated with a lower risk of BRAF-wild-type colorectal cancer but not with risk of BRAF-mutated cancer, findings that suggest that BRAF-mutant colon tumor cells may be less sensitive to the effect of aspirin, according to a study in the June 26 issue of JAMA.

26 Jun 2013

Prader-Willi syndrome results in dysregulation of circadian and metabolic genes

Researchers with the UC Davis MIND Institute and Agilent Laboratories have found that Prader-Willi syndrome - a genetic disorder best known for causing an insatiable appetite that can lead to morbid obesity - is associated with the loss of non-coding RNAs, resulting in the dysregulation of circadian and metabolic genes, accelerated energy expenditure and metabolic differences during sleep.

26 Jun 2013

Pretreatment PET staging of LS-SCLC associated with improved survival

Each year, 13 percent of all newly diagnosed lung cancer patients are diagnosed with small-cell lung cancer (SCLC). Approximately 39 percent of patients with SCLC are diagnosed with limited-stage disease, meaning the cancer is only present in one lung, but may have spread to lymph nodes or tissue between the lungs.

26 Jun 2013

Spontaneously emerging brain activity patterns preserve traces of previous cognitive activity

What if experts could dig into the brain, like archaeologists, and uncover the history of past experiences? This ability might reveal what makes each of us a unique individual, and it could enable the objective diagnosis of a wide range of neuropsychological diseases.

26 Jun 2013

Computerized brain-fitness program improves memory and language skills in older adults

UCLA researchers have found that older adults who regularly used a brain-fitness program on a computer demonstrated significantly improved memory and language skills.

26 Jun 2013

Hunger not only modifies behaviour, but also changes pathways in brain

Hungry people are often difficult to deal with. A good meal can affect more than our mood, it can also influence our willingness to take risks. This phenomenon is also apparent across a very diverse range of species in the animal kingdom.

26 Jun 2013

$Vitamin D and calcium supplements can prevent fractures$

Vitamin D and calcium supplements can prevent fractures

Should women take calcium and vitamin D supplements after menopause for bone health? Recommendations conflict, and opinions are strong. But now, an analysis from the major Women's Health Initiative (WHI) trial throws weight on the supplement side-at least for women taking hormones after menopause. The analysis was published online today in Menopause, the journal of The North American Menopause Society.

26 Jun 2013

PLK1 crucial for proper functioning of cancer cells, researchers reveal

One of the main indicators for determining the activity of a tumour or cancer is cell division. Cancer cells divide more than other types and the genes and molecules involved in the process of division are, often, targets for identifying and treating certain types of cancer.

26 Jun 2013

Controlled drug release using novel excipients: an interview with Dr Laura Waters, University of Huddersfield

When you take a medicine you may want the drug to all be released immediately or perhaps more slowly over a longer period of time. If we can make a medicine where we control the release then we can tailor our medicines to release at the exact rate we choose that is best for the patient.

26 Jun 2013

Report alerts clinicians, public about catastrophic dangers of contaminated epidural injections

Investigators from the Centers for Disease Control and Prevention describe pathologic findings from 40 case reports of fungal infection in patients who had been given contaminated epidural, paraspinal, or intra-articular (into joints) steroid injections and correlate these findings with clinical and laboratory data.

26 Jun 2013

Study explores analgesic activity of ceftriaxone in humans

A single dose of the antibiotic ceftriaxone given for antimicrobial prophylaxis prior to surgery enhanced patient pain thresholds after the procedure, according to a study published in The Journal of Pain, the peer review publication of the American Pain Society.

26 Jun 2013

Scientists examine molecular similarities in human and canine B-cell lymphoma

Humans and their pet dogs are close, so close that they both develop a type of cancer called diffuse large B-cell lymphoma. In humans it's the most common lymphoma subtype while in dogs, it's one of the most common cancers in veterinary oncology.

26 Jun 2013

Study: Active surveillance does not appear to be good idea for black men with prostate cancer

A Johns Hopkins study of more than 1,800 men ages 52 to 62 suggests that African-Americans diagnosed with very-low-risk prostate cancers are much more likely than white men to actually have aggressive disease that goes unrecognized with current diagnostic approaches.

26 Jun 2013

Karo Bio extends research collaboration with Pfizer on RORgamma modulators

Karo Bio AB announced today the extension of its existing research collaboration with Pfizer Inc. on RORgamma modulators to the end of 2014. Pfizer will continue to provide full funding for the research costs.

26 Jun 2013

Study examines increased use of new technologies for prostate cancer treatment

Use of advanced treatment technologies for prostate cancer, such as intensity-modulated radiotherapy and robotic prostatectomy, has increased among men with low-risk disease, high risk of noncancer mortality, or both, a population of patients who are unlikely to benefit from these treatments, according to a study in the June 26 issue of JAMA.

26 Jun 2013

Medical Research News

Study: Assessment of risk in patients who commit suicide and homicide is often poor

Findings suggest BRAF-mutant colon tumor cells may be less sensitive to the effect of aspirin

Prader-Willi syndrome results in dysregulation of circadian and metabolic genes

Pretreatment PET staging of LS-SCLC associated with improved survival

Spontaneously emerging brain activity patterns preserve traces of previous cognitive activity

Computerized brain-fitness program improves memory and language skills in older adults

Hunger not only modifies behaviour, but also changes pathways in brain

Vitamin D and calcium supplements can prevent fractures

PLK1 crucial for proper functioning of cancer cells, researchers reveal

Controlled drug release using novel excipients: an interview with Dr Laura Waters, University of Huddersfield

Report alerts clinicians, public about catastrophic dangers of contaminated epidural injections

Study explores analgesic activity of ceftriaxone in humans

Scientists examine molecular similarities in human and canine B-cell lymphoma

Study: Active surveillance does not appear to be good idea for black men with prostate cancer

Karo Bio extends research collaboration with Pfizer on RORgamma modulators

Study examines increased use of new technologies for prostate cancer treatment

A paradigm shift for treatment of muscular dystrophy

Caspase-2 protein contributes to cognitive decline associated with Alzheimer's disease

Researchers develop breakthrough approach to reduce harmful effects from blood transfusions

Weill Cornell researchers discover high burden of hypertension in sub-Saharan African country

Clue's CEO Rhiannon White on the Future of Femtech and PCOS

Freezing Point Osmometry in Life Science Applications

Precision in every drop: Inside Hamilton’s syringe technology

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