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Cedars-Sinai physician-scientist receives grant to study Charcot-Marie-Tooth disease

A Cedars-Sinai physician-scientist has been awarded a $3 million grant from the California Institute for Regenerative Medicine to study with new stem cell technology Charcot-Marie-Tooth disease, the most common inherited neurological disorder and which damages nerves that control muscles.

14 Dec 2012

Researchers identify how RecA protein helps broken DNA find way to bridge the gap

Every time a human or bacterial cell divides it first must copy its DNA. Specialized proteins unzip the intertwined DNA strands while others follow and build new strands, using the originals as templates. Whenever these proteins encounter a break - and there are many - they stop and retreat, allowing a new cast of molecular players to enter the scene.

14 Dec 2012

Banana leaf bandages effective and inexpensive

Banana leaves are a cheap and effective alternative to traditional medical wound dressings, as long as they are effectively sterilized before use, show study findings published in Dermatologic Surgery.

14 Dec 2012

Mobiles assist weight-loss interventions

Mobile phone technology can be used to enhance the effect of weight-loss programs, research shows.

14 Dec 2012

Challenge to brain injury guideline care

A randomized controlled trial has cast doubt on whether it is necessary to routinely place an intraparenchymal pressure monitor in patients with severe traumatic brain injury.

14 Dec 2012

God will control my asthma

Research shows that patients’ belief in God influences how likely they are to be adherent to asthma medication.

14 Dec 2012

Graphic images best anti-smoking message

The findings of a US study have backed the use of graphic imagery on cigarette packets to deter smoking.

14 Dec 2012

Diabetes risk increased in relatives of schizophrenia patients

The prevalence of diabetes is increased in the unaffected relatives of patients with non-affective psychosis, results from a Dutch study show.

14 Dec 2012

Cognitive therapy may reduce anxiety in bipolar patients

Mindfulness-based cognitive therapy may help reduce symptoms of anxiety in patients with bipolar disorder, researchers report.

14 Dec 2012

Combination therapy reduces sleep apnea symptoms at altitude

Patients with obstructive sleep apnea can better control their symptoms when traveling to higher altitudes by combining autoadjusted continuous positive airway pressure with acetazolamide, research suggests.

14 Dec 2012

Visual impairment and diabetes increase side by side

Visual impairment that is not explained by refractive error is increasing, as is the prevalence of diabetes – particularly diabetes lasting 10 years or longer, show US study results.

14 Dec 2012

Concern over enoxaparin bleeding risk in patients with moderate renal impairment

The low molecular weight heparin enoxaparin is associated with an increased risk for major bleeding in patients who have moderate renal impairment, say US scientists in findings that have prompted calls for updates to dosing recommendations.

14 Dec 2012

Definitions, responsibilities are crucial to medication reconciliation

To implement effective medication reconciliation, a definition of what the term means, as well as identification of who is responsible for the process, is necessary, show the results of a focus group-based study.

14 Dec 2012

High-risk leukemia patients respond to novel drug

A third of adult leukemia patients given the novel drug quizartinib during a phase II study have achieved a composite response of either complete remission, or remission with incomplete platelet recovery or incomplete hematologic recovery, report US researchers.

14 Dec 2012

Smoking ‘worsens hangovers’

People who smoke more than usual on the same day as drinking heavily are at increased risk for a hangover the following morning, with heavier smoking leading to a worse hangover, researchers say.

14 Dec 2012

Perthes’ disease link to congenital disorders revealed

Researchers have linked Perthes' disease with several congenital conditions, pointing to intra-uterine factors behind the development of the disease.

14 Dec 2012

Malaria vaccine trial: an interview with Professor Sir Brian Greenwood

Malaria is an infection caused by a parasite called plasmodium, which is transmitted from person to person by females of some species of mosquito. It is primarily a disease of tropical countries.

14 Dec 2012

Simple screening test of musculo-skeletal fitness proves predictive of all-cause mortality

A simple screening test of musculo-skeletal fitness has proved remarkably predictive of all-cause mortality in a study of more than 2000 middle-aged and older men and women.

14 Dec 2012

Time restrictions on television do not reduce underage exposure to alcohol advertising

Efforts to reduce underage exposure to alcohol advertising by implementing time restrictions have not worked, according to new research from the Center on Alcohol Marketing and Youth (CAMY) at the Johns Hopkins Bloomberg School of Public Health and the Dutch Institute for Alcohol Policy.

14 Dec 2012

More than two-thirds of generic drugs have incomplete or incorrect safety-warning labels

Despite U.S. Food and Drug Administration regulations requiring generic medications to carry identical warnings to those on corresponding brand-name products, a study by Regenstrief Institute researchers has found that more than two-thirds of generic drugs have safety-warning labels that differ from the equivalent brand-name drug.

14 Dec 2012