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Scientists identify new therapeutic targets to inhibit progression of Alzheimer's disease

To stop the progression of Alzheimer's disease in the early stage, it is necessary to identify new therapeutic targets. Prof. Yunpeng Cao and team from the First Affiliated Hospital of China Medical University examined striatal-enriched phosphatase 61 expression in the brain tissues of Alzheimer's disease rats using in vivo and in vitro models, and analyzed the molecular mechanism by which striatal-enriched phosphatase 61 regulates N-methyl-D- aspartate receptor 2B transport.

17 Aug 2013

Researchers study demographic, socioeconomic factors that buffer effects of video game violence

In November 2010, an online gaming company called ActiVision released Call of Duty: Black Ops, a violent, first-person shooter game compatible with a variety of gaming devices. The video game sold 5.6 million copies within 24 hours of its release, and it earned a record-breaking $650 million in its first five days. Six weeks later, the game had exceeded $1 billion in sales.

17 Aug 2013

Increased caffeine intake may reduce fatty liver in people with NAFLD

Surprise! Your morning cup of tea or coffee may be doing more than just perking you up before work. An international team of researchers led by Duke-NUS Graduate Medical School (Duke-NUS) and the Duke University School of Medicine suggest that increased caffeine intake may reduce fatty liver in people with non-alcoholic fatty liver disease (NAFLD).

17 Aug 2013

UCSF study shows potential for new treatment strategy for Parkinson’s disease

UC San Francisco scientists working in the lab used a chemical found in an anti-wrinkle cream to prevent the death of nerve cells damaged by mutations that cause an inherited form of Parkinson-s disease.

17 Aug 2013

Autistic children demonstrate superior math skills compared with normal children in same IQ range

Children with autism and average IQs consistently demonstrated superior math skills compared with nonautistic children in the same IQ range, according to a study by researchers at the Stanford University School of Medicine and Lucile Packard Children's Hospital.

17 Aug 2013

Study shows lymph node location influences maturation process of cells they contain

Based on their observations, the scientists deduced that lymph node location influences the maturation process of the cells they contain. "The cells retained their original skills for weeks following the transplant," says Dr. Sascha Cording, one of the study's first authors. "You might say lymph nodes have something like a location-specific memory."

17 Aug 2013

ATSP-7041 stapled peptide activates p53, suppresses tumor growth in animal models

Aileron Therapeutics, Inc., a clinical stage biopharmaceutical company that is developing first-in-class therapeutics based on its proprietary Stapled Peptide drug platform, announced today the publication of preclinical data on ATSP-7041, a potent and selective stapled peptide re-activator of the wild type p53 tumor suppressor protein.

17 Aug 2013

Novel way of observing electrical response in brain before and during fall through EEG

It's always in front of a million people and feels like eternity. You're strolling along when suddenly you've stumbled-the brain realizes you're falling, but your muscles aren't doing anything to stop it.

17 Aug 2013

BIDMC cardiovascular research team receives $4M grant to identify mRNA biomarkers in heart disease

A cardiovascular research team from Beth Israel Deaconess Medical Center (BIDMC) and Brigham and Women's Hospital (BWH), led by BIDMC Principal Investigator Saumya Das, MD, PhD, has been awarded a $4 million Common Fund grant from the National Institutes of Health (NIH) as part of a newly formed program on Extracellular RNA Communication.

17 Aug 2013

High cholesterol level is more detrimental for middle aged men than women

High cholesterol levels are much more risky for middle-aged men than middle-aged women when it comes to having a first heart attack, a new study of more than 40,000 Norwegian men and women has shown.

17 Aug 2013

Scientists develop new therapies to prevent chemoresistance of established tumours

Cancer cells often develop defence mechanisms which enable them to survive chemotherapy. A group of researchers from the Institutes of Pharmacology and Pathology in Bern present new solutions for preventing the development of such resistances.

17 Aug 2013

Inflating blood pressure cuff ahead of heart bypass surgery reduces heart injury

Inflating a blood pressure cuff on the upper arm just ahead of heart bypass surgery reduces heart injury and might even improve bypass patients’ long-term survival, according to an Article published in The Lancet.

16 Aug 2013

Prion proteins responsible for Mad cow disease, Creutzfeld-Jakob disease

Mad cow disease and its cousin Creutzfeld-Jakob disease cause fatal spongy changes in brain tissue. Today, we know that these diseases are caused by prions, proteins that are folded incorrectly. A team of German researchers have now been able to follow how the diseased proteins aggregate and "infect" healthy ones on the atomic scale. Their report appears in the journal Angewandte Chemie.

16 Aug 2013

GHI nutrition researchers find secret to hydrating beer

Nutrition researchers at the Griffith Health Institute have found that it’s possible to improve the hydrating effects of beer, without killing off its taste. Therefore people who enjoy a cold one at the end of a hard day’s labour won’t be at risk of dehydration.

16 Aug 2013

GHI research aims to target breast cancer stem-like cells using immunotherapy

New hope is on its way for the fight against breast cancer as Griffith Health Institute research aims to target the disease with immune-based therapies.

16 Aug 2013

Scientists shed new light on molecular causes of age related degenerative disease

An international collaboration jointly led by scientists from Trinity College Dublin has shed new light on the origins and molecular causes of age related degenerative conditions including Motor Neurone Disease (MND). The new perspective provided by this work may lead the way to new treatments and early diagnoses.

16 Aug 2013

Study provides information that validates genetic basis of adaptation to high altitudes

Research led by scientists from the University of California, San Diego has decoded the genetic basis of chronic mountain sickness (CMS) or Monge's disease. Their study provides important information that validates the genetic basis of adaptation to high altitudes, and provides potential targets for CMS treatment.

16 Aug 2013

Irrelevant information leads to inappropriate treatment decisions in medical testimonials

Medical testimonials on the Internet and elsewhere present powerful personal stories and useful information, but they can also be dangerous to your health if distracting, irrelevant information leads to inappropriate treatment decisions, say researchers at the University of North Carolina at Chapel Hill.

16 Aug 2013

Study: Herniated discs result from avulsion of tissue, rather than rupture

Herniated discs in the lower (lumbar) spine most often result from avulsion (separation) of the tissue connection between the disc and spinal bone, rather than rupture of the disc itself, according to a study in Spine. The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health.

16 Aug 2013

Researchers make significant advancement in childhood cancer

A significant advance in the understanding of a childhood cancer called Neuroblastoma has been made by scientists from the Smurfit Institute of Genetics at Trinity College Dublin.

16 Aug 2013

Medical Research News

Scientists identify new therapeutic targets to inhibit progression of Alzheimer's disease

Researchers study demographic, socioeconomic factors that buffer effects of video game violence

Increased caffeine intake may reduce fatty liver in people with NAFLD

UCSF study shows potential for new treatment strategy for Parkinson’s disease

Autistic children demonstrate superior math skills compared with normal children in same IQ range

Study shows lymph node location influences maturation process of cells they contain

ATSP-7041 stapled peptide activates p53, suppresses tumor growth in animal models

Novel way of observing electrical response in brain before and during fall through EEG

BIDMC cardiovascular research team receives $4M grant to identify mRNA biomarkers in heart disease

High cholesterol level is more detrimental for middle aged men than women

Scientists develop new therapies to prevent chemoresistance of established tumours

Inflating blood pressure cuff ahead of heart bypass surgery reduces heart injury

Prion proteins responsible for Mad cow disease, Creutzfeld-Jakob disease

GHI nutrition researchers find secret to hydrating beer

GHI research aims to target breast cancer stem-like cells using immunotherapy

Scientists shed new light on molecular causes of age related degenerative disease

Study provides information that validates genetic basis of adaptation to high altitudes

Irrelevant information leads to inappropriate treatment decisions in medical testimonials

Study: Herniated discs result from avulsion of tissue, rather than rupture

Researchers make significant advancement in childhood cancer

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