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Scientist develop mathematical model that predicts how individuals respond to cancer treatment

Vittorio Cristini, PhD, uses the example of an airplane to explain what he does in cancer research. "Before calculus," he says, "people couldn't really design a plane that would fly. You can do it by trial and error, but it would probably take centuries." Dr. Cristini has a faster way to try to understand cancer treatment. Like airplane designers today, he uses a mathematical model.

13 Aug 2013

Scientist receives grant to examine protein trigger involved in cell function regulation in breast cancer

The New Jersey Commission on Cancer Research (NJCCR) has awarded Janice Thomas, PhD, a post-doctoral fellow in the X.F. Steven Zheng laboratory at Rutgers Cancer Institute of New Jersey a two-year $100,000 grant (#DFHS13PPCO32) to further examine the impact of a protein 'trigger' involved in the regulation of cell function in breast cancer.

13 Aug 2013

Study reveals adolescents with ADHD may have driving deficits

A study using a driving simulator suggests that adolescents with attention-deficit/hyperactivity disorder (ADHD) who were distracted while driving demonstrated more variability in speed and lane position than adolescents without ADHD, according to a study published by JAMA Pediatrics, a JAMA Network publication.

13 Aug 2013

Study: Strain of bacteria infections in humans originally come from cattle

A strain of bacteria that causes skin and soft tissue infections in humans originally came from cattle, according to a study to be published in mBio-, the online open-access journal of the American Society for Microbiology.

13 Aug 2013

Study: H3 receptor antagonist can improve brain edema in adult hypoxic rats

Thioperamide, a selective histamine H3 receptor antagonist, can increase histamine content in the brain and improve brain edema in adult hypoxic rats. Brain edema is precisely considered as the important pathological change of neonatal hypoxic-ischemic encephalopathy.

13 Aug 2013

Durin receives grant to expand novel blood test that can detect Parkinson's

The Michael J. Fox Foundation for Parkinson's Research has awarded Durin Technologies, Inc., a grant of $351,200 to expand the development of Durin's novel blood test that can detect the presence of Parkinson's disease.

13 Aug 2013

New research opens door for development of treatments capable of stopping Alzheimer's disease

New research just out in the journal Science Translational Medicine opens the door for the development of treatments capable of stopping Alzheimer's disease (AD) before its first symptoms, that is to say before any crucial damage occurs. In fact, if AD is a devastating disorder it is also an extremely slow one; it takes more than 10 years for the first symptoms to appear making this preclinical period (pre-symptoms) the ideal time to intervene.

13 Aug 2013

Flexible hubs coordinate brain’s responses to novel cognitive challenges

One thing that sets humans apart from other animals is our ability to intelligently and rapidly adapt to a wide variety of new challenges - using skills learned in much different contexts to inform and guide the handling of any new task at hand.

13 Aug 2013

Strategy that dismantles flu viral genome in human lung cells ensures safe research

A new strategy that dismantles a viral genome in human lung cells will ensure safe research on deadly strains of influenza, say researchers from the Icahn School of Medicine at Mount Sinai.

13 Aug 2013

Emory’s Yerkes Research Center receives $9.5M grant to establish research center to study oxytocin

The Yerkes National Primate Research Center, Emory University, has received a five-year, $9.5 million grant from the National Institute of Mental Health (NIMH) to establish a Silvio O. Conte Center in Neuroscience Research to study oxytocin, a brain chemical known for forming bonds between mother and baby.

13 Aug 2013

Vitamin D supplementation does not improve blood pressure in hypertension patients

Vitamin D supplementation does not appear to improve blood pressure or markers of vascular health in older patients with isolated systolic hypertension (a common type of high blood pressure), according to a study by Miles D. Witham, Ph.D., of the University of Dundee, Scotland, United Kingdom, and colleagues.

13 Aug 2013

Cedars-Sinai launches Phase I clinical trial to study tolerability of immunization to treat Alzheimer's disease

Cedars-Sinai Medical Center has launched a Phase I clinical trial to study the safety and tolerability of an experimental immunization to treat Alzheimer's disease. The treatment is based on Copaxone (glatiramer acetate), a drug often prescribed to reduce the frequency of multiple sclerosis relapses.

13 Aug 2013

Patients with rare epilepsy aphasia share mutations on same gene

Some patients with a rare type of epilepsy called epilepsy aphasia have something else in common. They have mutations in the same gene. Epilepsy aphasia disorders are characterized by seizures and speech abnormalities.

13 Aug 2013

Bacterial strains that delay cell division might be used to design drugs that stop division entirely

In 1958 a group of scientists working in Denmark made the striking observation that bacterial cells are about twice as large when they are cultured on a rich nutrient source than when they are cultured on a meager one.

13 Aug 2013

Simple tests to recognize ability of famous people may help doctors identify early dementia

A new study suggests that simple tests that measure the ability to recognize and name famous people such as Albert Einstein, Bill Gates or Oprah Winfrey may help doctors identify early dementia in those 40 to 65 years of age.

13 Aug 2013

Researchers say type 2 diabetes status should be taken into account in future BMI-mortality studies

The relationship between body mass index (BMI) appears to be stronger in adults without diabetes than those with existing diabetes. These findings- are published in the Journal of General Internal Medicine- in a study by Chandra Jackson of the Harvard School of Public Health and colleagues.

13 Aug 2013

Researchers suggest neural stem cells may regenerate after anti-cancer treatment

Scientists have long believed that healthy brain cells, once damaged by radiation designed to kill brain tumors, cannot regenerate. But new Johns Hopkins research in mice suggests that neural stem cells, the body's source of new brain cells, are resistant to radiation, and can be roused from a hibernation-like state to reproduce and generate new cells able to migrate, replace injured cells and potentially restore lost function.

13 Aug 2013

Patients with IBS-D treated with eluxadoline achieve better clinical response

Patients with diarrhea-predominant irritable bowel syndrome, or IBS-D, treated with eluxadoline achieved better clinical response and experienced more symptom improvement than those using placebo, according to a recent study in Gastroenterology, the official journal of the American Gastroenterological Association. Eluxadoline, which is currently in phase 3 trials, is under development as a potential treatment for IBS-D.

13 Aug 2013

Harvard University receives grant to use organs-on-chips device to test human response to radiation

A team at the Wyss Institute for Biologically Inspired Engineering at Harvard University has received a $5.6 million grant award from the United States Food and Drug Administration (FDA) to use its Organs-on-Chips technology for a novel application of keen interest to national security and health officials: to test human physiological responses to radiation, and to evaluate drugs designed to counter those effects.

13 Aug 2013

Study provides clues to improve treatment of neuroblastoma with suppressor gene

Loss of a gene required for stem cells in the brain to turn into neurons may underlie the most severe forms of neuroblastoma, a deadly childhood cancer of the nervous system, according to a Ludwig Cancer Research study.

13 Aug 2013

Medical Research News

Scientist develop mathematical model that predicts how individuals respond to cancer treatment

Scientist receives grant to examine protein trigger involved in cell function regulation in breast cancer

Study reveals adolescents with ADHD may have driving deficits

Study: Strain of bacteria infections in humans originally come from cattle

Study: H3 receptor antagonist can improve brain edema in adult hypoxic rats

Durin receives grant to expand novel blood test that can detect Parkinson's

New research opens door for development of treatments capable of stopping Alzheimer's disease

Flexible hubs coordinate brain’s responses to novel cognitive challenges

Strategy that dismantles flu viral genome in human lung cells ensures safe research

Emory’s Yerkes Research Center receives $9.5M grant to establish research center to study oxytocin

Vitamin D supplementation does not improve blood pressure in hypertension patients

Cedars-Sinai launches Phase I clinical trial to study tolerability of immunization to treat Alzheimer's disease

Patients with rare epilepsy aphasia share mutations on same gene

Bacterial strains that delay cell division might be used to design drugs that stop division entirely

Simple tests to recognize ability of famous people may help doctors identify early dementia

Researchers say type 2 diabetes status should be taken into account in future BMI-mortality studies

Researchers suggest neural stem cells may regenerate after anti-cancer treatment

Patients with IBS-D treated with eluxadoline achieve better clinical response

Harvard University receives grant to use organs-on-chips device to test human response to radiation

Study provides clues to improve treatment of neuroblastoma with suppressor gene

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