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Neural clues found for impaired emotional response in bipolar disorder

Researchers have identified distinct trait- and state-related neural abnormalities during emotional response inhibition in patients with bipolar disorder.

22 Jan 2013

Tell tale neurologic soft signs for schizophrenia and bipolar disorder

Neurologic soft signs can differentiate schizophrenia from major depression but not bipolar disorder, study findings indicate.

22 Jan 2013

Simulation ticks box for checklists in surgical care

The management of operating-room crises could be significantly improved by using checklists, say researchers in the New England Journal of Medicine.

22 Jan 2013

Routine gastric volume monitoring thrown out

Monitoring gastric residual volumes in critically ill patients receiving enteral nutrition does not prevent them from developing ventilator-associated pneumonia, shows a randomized trial.

22 Jan 2013

Eardrum crust aids perforation healing if timing is right

How and when “crust” forms at the margin of a tympanic membrane perforation may serve as a predictor for healing outcome, research suggests.

22 Jan 2013

Ultrasound strategy excludes DVT in pregnant women

Serial compression ultrasonography with iliac vein visualization can reliably exclude deep vein thrombosis in symptomatic pregnant women, according to results from an 8-year prospective cohort study published in the Canadian Medical Association Journal.

22 Jan 2013

STN confirmed as preferred stimulation target in Parkinson’s

Subthalamic nucleus stimulation is at worst equivalent and at best superior to globus pallidus pars interna stimulation in patients with Parkinson’s disease, shows a randomized trial.

22 Jan 2013

Team support aids Parkinson’s patients

A randomized controlled trial demonstrates improved outcomes if patients with Parkinson’s disease are cared for by a multidisciplinary team.

22 Jan 2013

Amyloid clue to Parkinson’s dementia

Study findings link amyloid β burden to future cognitive decline in patients with Parkinson’s disease.

22 Jan 2013

Imaging supports Braak Parkinson’s staging

A magnetic resonance imaging study supports the hypothesis that degeneration occurs in the substantia nigra pars compacta before the basal forebrain in patients with Parkinson’s disease.

22 Jan 2013

Chronic heart failure treatment, Inspra (eplerenone), accepted for use within NHS Wales

Inspra (eplerenone) has now been accepted by the All Wales Medicines Strategy Group (AWMSG) for use in adult patients with chronic heart failure (CHF) NYHA class II, in combination with standard optimal therapy...

22 Jan 2013

Suppression of immune system function can occur in influenza patients

Investigators from 15 children's medical centers, including Nationwide Children's Hospital, observed and evaluated critically ill children with influenza to evaluate the relationships between levels of systemic inflammation, immune function and likelihood to die from the illness. The study appears in the January issue of Critical Care Medicine.

22 Jan 2013

Family members with rare gene mutation at high risk of developing schizophrenia

Johns Hopkins researchers have identified a rare gene mutation in a single family with a high rate of schizophrenia, adding to evidence that abnormal genes play a role in the development of the disease.

22 Jan 2013

Study indicates rate of ADHD diagnosis has increased from 2001 to 2010

A study of medical records at the Kaiser Permanente Southern California health plan suggests the rate of attention-deficit/hyperactivity disorder (ADHD) diagnosis increased from 2001 to 2010, according to a report published Online First by JAMA Pediatrics, a JAMA Network publication.

22 Jan 2013

Study reveals ugly cholesterol is the direct cause of ischaemic heart disease

The risk of ischaemic heart disease - a disease affecting some 150,000 Danes - is three times higher in persons with high levels of the so-called 'ugly' cholesterol. This is the finding of a new study of 73,000 Danes, which is shedding light on a long debate on this topic. The results have just been published in the Journal of the American College of Cardiology.

22 Jan 2013

Hearing loss is associated with accelerated cognitive decline and impairment in older adults

Hearing loss appears to be associated with accelerated cognitive decline and cognitive impairment in a study of older adults, according to a report published Online First by JAMA Internal Medicine, a JAMA Network publication.

22 Jan 2013

Schizophrenics more likely to die from cardiovascular disease and cancer

A new study from Lund University in Sweden shows that the average life expectancy of men and women with schizophrenia is 15 years and 12 years shorter respectively than for those who do not suffer from the disease.

22 Jan 2013

BRCA1-deficient cancer cells take advantage of DNA repair mechanism

Cancer cells are resourceful survivors with plenty of tricks for staying alive. Researchers have uncovered one of these stratagems, showing how cells lacking the tumor suppressor BRCA1 can resume one form of DNA repair, sparing themselves from stagnation or death. The study appears in the January 21st issue of The Journal of Cell Biology.

22 Jan 2013

Research into effects of cyber bullying, online relationships and social media

When we typically think of kids who are the victims of school bullying, what comes to mind are isolated youth who do not fit in. A new study, however, shows that when that harassment occurs online, the victims tend to be in mainstream social groups at the school - and they are often friends or former friends, not strangers.

21 Jan 2013