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Transcription factor expression aids stage I lung cancer prognosis

Expression of thyroid transcription factor-1 is an independent predictor for recurrence of stage I lung adenocarcinoma and allows intermediate-grade tumors to be split into two prognostic subsets, scientists have found.

16 Nov 2012

Fibulin-3 effective biomarker for pleural mesothelioma

Research suggests that levels of fibulin-3 in plasma and effusions may aid in determining the diagnosis and prognosis of pleural mesothelioma.

16 Nov 2012

Cinacalcet failure raises trial conduct issues

The oral calcimimetic agent, cinacalcet, has been found to have no significant effect on cardiovascular events or death in patients with chronic kidney disease in a randomized controlled trial.

16 Nov 2012

Hydrocortisone protects bilateral knee replacement patients

Repeat doses of corticosteroids may protect patients undergoing bilateral total knee arthroplasty from postoperative side effects such as fever, pain, and acute respiratory distress, research suggests.

16 Nov 2012

Images of diseased organs have most impact on smokers

Labels that use graphic images as warnings on cigarette packaging have the most pronounced impact on adult smokers compared with other images or text-only labels, say researchers.

16 Nov 2012

Hearing impairment risk high with diabetes

People with diabetes are at high risk for developing a hearing impairment, report researchers.

16 Nov 2012

Latest in optometry: headache link debunked; iPads open up new vista

The latest research in optometry finds no link between headaches and refractive errors in children under the age of 18 years – and a clinical purpose for iPads.

16 Nov 2012

'Extended-skill' nurses, physiotherapists are as effective as the ER doc

Patients with peripheral soft tissue injuries achieve similar clinical outcomes when treated by emergency nurse practitioners and extended-scope physiotherapists in the emergency department, as when they are treated by doctors, show UK study results.

16 Nov 2012

Vitiligo patients have low risk for skin cancer

Evidence suggests that patients with vitiligo have a reduced risk for both melanoma and nonmelanoma skin cancer.

16 Nov 2012

Caterpillar fungi may benefit asthma patients

Research shows that cordycepin, extracted from a group of rare parasitic caterpillar fungi of the genus Cordyceps, has unusual anti-inflammatory properties that may make it a good candidate for treating conditions such as asthma and rheumatoid arthritis.

16 Nov 2012

Obstetric complications linked to NSS in schizophrenia

Patients with schizophrenia whose mothers experienced obstetric complications during pregnancy show more neurologic soft signs than those with mothers who did not experience such complications, researchers report.

16 Nov 2012

Risk for adverse pregnancy outcomes increased in bipolar women

Women with bipolar disorder are at increased risk for adverse pregnancy outcomes, results from a Swedish study show.

16 Nov 2012

Imaging technique could give early aneurysm rupture warning

The speed of ferumoxytol uptake on magnetic resonance imaging may indicate if a cerebral aneurysm is unstable and likely to rupture soon, say US researchers.

16 Nov 2012

Periodicity Index limits variability when measuring restless legs

The Periodicity Index is a more stable measure of leg movements during sleep in restless legs syndrome than the widely used periodic leg movements index, investigators have found.

16 Nov 2012

Experts call for global treaty on drug quality

Professionals from the world of health, including health charities, legal and medical academia, and former or current government health officials, have called for the creation of an internationally binding treaty to tackle illegitimate drugs.

16 Nov 2012

Potential to reduce preterm births ‘shockingly small’

If developed countries were to successfully implement five preventive interventions, only a 5% relative reduction in the preterm birth rate could be achieved by 2015, shows a study published by The Lancet.

16 Nov 2012

Combined exercise approach may help Parkinson’s patients

A mixture of gait training and strengthening exercises may be beneficial for patients with Parkinson’s disease, suggest findings from a randomized trial.

16 Nov 2012

Brain imaging distinguishes Parkinson’s subtypes

Patients with nontremor-dominant Parkinson’s disease show changes in brain activity that set them apart from tremor-dominant patients and from healthy controls, a study shows.

16 Nov 2012

Bradykinesia is ‘context-specific’ in Parkinson’s

Patients with Parkinson’s disease can make rapid responses to avoid adverse stimuli, but cannot speed up their actions to gain a reward, report UK researchers.

16 Nov 2012

Study examines public health impact of tamper resistant extended-release oxycodone

This is the first epidemiological study to examine the public health impact of a tamper resistant extended-release oxycodone (ORF). ER oxycodone was reformulated with physicochemical barriers to crushing and dissolving intended to reduce abuse through non-oral routes of administration.

16 Nov 2012