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Tricuspidization preferred for unicuspid aortic valve repair

Unicuspid aortic valves may be reconstructed with tricuspidization using glutaraldehyde-treated autologous pericardium, with excellent early results and no mortality or major morbidity, the results of a preliminary study suggest.

22 Oct 2012

Thiol peroxidase involved in S. pneumoniae defenses

The Streptococcus pneumoniae bacteria defends itself from high levels of hydrogen peroxide with the help of thiol peroxidase, research shows.

22 Oct 2012

Mother–baby intensive care admission carries high mortality risk

Mothers and newborns who are both admitted to an intensive care unit are significantly more likely to die than mother–baby pairs who are not, a study suggests.

22 Oct 2012

Sleep symptoms impair fibromyalgia patients’ QoL

A study of fibromyalgia patients highlights the impact of sleep symptoms on health-related quality of life in this population.

22 Oct 2012

$Ustekinumab success in refractory Crohn’s disease$

Ustekinumab success in refractory Crohn’s disease

Patients with Crohn’s disease who have failed to respond adequately to anti–tumor necrosis factor treatment may benefit from the monoclonal antibody ustekinumab, results of a double-blind, placebo-controlled trial suggest.

22 Oct 2012

Researchers continue hunt for AIDS vaccine

"Finding a safe, effective AIDS vaccine has, thus far, proved elusive even after some $8 billion invested from 2001-2011 into vaccine research and development," PlusNews reports in an article examining ongoing HIV vaccine research efforts. "Scientists point to HIV's Houdini-like ability to escape immune system attack, and less-than-strategic use of funds over the past decade, as reasons for the continued hunt," the news service writes.

22 Oct 2012

Stress in parents linked to obesity in their children

Parents with a higher number of stressors in their lives are more likely to have obese children, according to a new study by pediatric researchers. Furthermore, when parents perceive themselves to be stressed, their children eat fast food more often, compared to children whose parents feel less stressed.

22 Oct 2012

Malignant melanoma cases increase in Sweden

Malignant melanoma is as much as 35% more common among people who live in Gothenburg and the region's coastal municipalities than those who live inland. Researchers at Sahlgrenska Academy, University of Gothenburg, Sweden, have found that the number of malignant melanoma cases in the Västra Götaland region has quadrupled since 1970.

22 Oct 2012

Patients with chronic constipation at increased risk of colorectal cancer, benign neoplasms

Patients with chronic constipation may be at increased risk of developing colorectal cancer and benign neoplasms, according to study findings unveiled today at the American College of Gastroenterology's (ACG) 77th Annual Scientific meeting in Las Vegas.

22 Oct 2012

EvaluatePharma's Tracking Drugs@FDA provides regulatory approval analysis

EvaluatePharma, the premier source for life science sector analysis and consensus forecasts, today launched a new service enhancement, Tracking Drugs@FDA, which gives clients access to the entire universe of approved FDA drugs and the related FDA document library as well as FDA Orange Book patent data - all fully integrated into the industry-leading EvaluatePharma platform and analytical tools.

22 Oct 2012

Acetylsalicylic acid slows decline in brain capacity among the elderly

A daily dose of acetylsalicylic acid equivalent to a fourth of an aspirin may slow the decline in intellectual capacity among elderly individuals with high cardiovascular risk. This is shown in a study by Sahlgrenska Academy, University of Gothenburg, Sweden.

22 Oct 2012

Emotion and perception not fully dissociable in the mind

That snake heading towards you may be further away than it appears. Fear can skew our perception of approaching objects, causing us to underestimate the distance of a threatening one, finds a study published in Current Biology.

22 Oct 2012

Short-term secondhand smoke exposure can lead to airway restriction

Heavy concentrations of secondhand smoke, such as those found in smoke-filled bars and cars, can lead to airway restriction for bystanders within minutes of exposure. The study, presented at CHEST 2012, the annual meeting of the American College of Chest Physicians, showed that after 20 minutes of exposure to highly concentrated secondhand smoke, participants experienced near immediate physiologic changes, including airway resistance and impedance.

22 Oct 2012

Obese patients may have advantages in certain health situations

Although obesity is linked to a variety of health risks, new research indicates that obese patients may have an advantage over nonobese patients in certain health situations, including septic shock and acute asthma exacerbation.

22 Oct 2012

Insight into calcium pumps in cells

When animals and plants are exposed to influences such as bacterial attack, odour and cold, calcium ions flow into the cells. The calcium provides the cells with a signal about what is going on outside, but as high concentrations of calcium are toxic to the cells, it must be quickly pumped out again.

22 Oct 2012

Implementation of 24-h intensivist staffing model reduces mortality rates, length of stay

The implementation of a 24-h ICU in-house staff intensivist coverage was associated with improved mortality rates and reduced length of stay, along with quicker decision-making and a positive trend in quality of end-of-life care.

22 Oct 2012

Cough, difficulty breathing and chest pain key symptoms of pulmonary embolism

Difficulty breathing, chest pain, and cough may sound like symptoms of a heart attack; however, new research shows that these are the key symptoms for pulmonary embolism (PE), a potentially fatal blockage in the lung.

22 Oct 2012

Simple 10-minute Tension Tamer could help relieve stress and decrease fatigue

A simple, 10-minute stress reduction technique could help to relieve stress, improve sleep quality, and decrease fatigue.

22 Oct 2012

High school students experience excessive daytime sleepiness: Study

New research shows that high school students experience excessive daytime sleepiness (EDS), with most students sleeping fewer than 7 hours per night.

22 Oct 2012

Alcohol consumption, college education may increase risk of COPD

College education and alcohol consumption may be linked to risk for chronic obstructive pulmonary disease (COPD). Researchers from Kaiser Permanente Medical Group in Oakland, California, followed 126,019 people who supplied baseline data from 1978 - 1985 through 2008 with analyses of hospitalizations attributed to COPD (emphysema, chronic bronchitis, or chronic airway obstruction).

22 Oct 2012