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Quinic acid derivative shows promise for treating radiation exposure

A quinic acid derivative, known as KZ-41, increases 30-day survival threefold compared with placebo when given to rats 24 hours after exposure to high levels of radiation.

17 Oct 2012

Cytokine levels altered in FEP, schizophrenia patients

Levels of certain cytokines are altered in patients with first-episode psychosis and patients with schizophrenia, research shows.

17 Oct 2012

Nonpsychiatric medical costs high in bipolar disorder patients

The use of nonpsychiatric healthcare services is greater and associated costs higher in bipolar disorder patients than in those without the mood disorder, results from a Taiwanese study show.

17 Oct 2012

Tool reveals myeloproliferative neoplasm patient burden

Researchers have devised a tool to accurately assess the extent of symptoms in patients with myeloproliferative neoplasms.

17 Oct 2012

Genetic signatures for aggressive prostate cancer identified

Researchers have identified two genetic signatures for castration-resistant prostate cancer that may predict the severity of the disease.

17 Oct 2012

HIV infection has been major driver of anal cancer burden

Rising rates of anal cancer among men in the USA have been heavily influenced by the HIV epidemic since the 1980s, a study shows.

17 Oct 2012

Botulinum treatment benefits in BPH maybe down to placebo effect

Treatment with botulinum toxin has proved no more effective than placebo at reducing symptoms in men with lower urinary tract symptoms due to benign prostate hyperplasia, show study findings.

17 Oct 2012

Vision care providers worry about effect of reporting driving concerns

Two-thirds of vision care providers routinely enquire about their older patients’ driving, while almost half believe that reporting patients negatively to government agencies affects the physician–patient relationship, show US study results.

17 Oct 2012

Quitting smoking may improve HRQoL in advanced lung cancer

The health-related quality of life of patients with advanced-stage lung cancer is worsened if they smoke, report UK researchers.

17 Oct 2012

Asian and Pacific Islander diabetes data need segregating

Surveillance statistics that aggregate Asians and Pacific Islanders are misleading in terms of establishing who would benefit most from increased diabetes prevention interventions, report US researchers.

17 Oct 2012

Maintain dogs’ presurgery warmth to avoid hypothermia

Hypothermia is common in dogs after undergoing surgery under anesthetic, especially for diagnostic procedures and when the animal is in poor condition, research indicates.

17 Oct 2012

Intermediate-acting neuromuscular block use ‘needs revisiting’

The use of intermediate-acting neuromuscular blocking agents during general anesthesia may increase the risk for clinically meaningful respiratory complications, researchers report in the BMJ.

17 Oct 2012

Dopaminergic treatment has ‘minor impact’ on autonomic symptoms in Parkinson’s

Norwegian researchers say that dopaminergic treatment should be considered for patients with early Parkinson’s disease after finding that dopaminergic medication only has a minor impact on autonomic symptoms after 1 year.

17 Oct 2012

High-carb diet may increase risk of mild cognitive impairment among older people

People 70 and older who eat food high in carbohydrates have nearly four times the risk of developing mild cognitive impairment, and the danger also rises with a diet heavy in sugar, Mayo Clinic researchers have found.

17 Oct 2012

Fathers' parenting behavior influences sexual behavior of their adolescent children

A new study by New York University professor Vincent Guilamo-Ramos and colleagues from the Centers for Disease Control and Prevention (CDC) suggests that fathers' parenting behavior influences the sexual behavior of their adolescent children.

17 Oct 2012

Northwestern scientists to request EPA to update guidelines for reproductive health research

A team of Northwestern University scientists will meet with Environmental Protection Agency (EPA) administrators in Washington D.C. Oct. 18 to advocate for important changes in the agency's guidelines for reproductive health research.

17 Oct 2012

People in creative professions are treated more often for mental illness

People in creative professions are treated more often for mental illness than the general population, there being a particularly salient connection between writing and schizophrenia. This according to researchers at Karolinska Institutet in Sweden, whose large-scale registry study is the most comprehensive ever in its field.

17 Oct 2012

Study finds overall decline in cholesterol levels among U.S. adults

An analysis of nationally-representative data indicates that between 1988 and 2010 there has been a trend of declining average levels of total cholesterol, non-high-density lipoprotein cholesterol, and low-density lipoprotein cholesterol for U.S. adults overall, according to a study in the October 17 issue of JAMA.

17 Oct 2012

Patient-reported outcomes should be assessed in comparative effectiveness of cancer treatments

Patient-reported outcomes should be a standard part of evaluating the comparative effectiveness of cancer treatments, according to recommendations put forward by a multi-institution research group.

17 Oct 2012

UAF scientists discover evolutionary origin of air breathing in vertebrates

University of Alaska Fairbanks scientists have identified what they think is the ancestral trait that allowed for the evolution of air breathing in vertebrates. They will present their research at the 42nd annual meeting of the Society for Neuroscience Oct. 17 in New Orleans.

17 Oct 2012