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Recombinant protein may treat male factor fertility

Male factor infertility resulting in failed oocyte activation from dysfunctional sperm phospholipase C-zeta may be remedied through the use of a recombinant form of the protein, leading to efficient blastocyst formation, say scientists.

8 Oct 2012

Genetic basis of uterine fibroids uncovered

A mutation located near the fatty acid synthase gene is associated with an increased predisposition for uterine leiomyomata or fibroids, suggest US study findings.

8 Oct 2012

Best-practices protocol significantly reduces ventilator-associated pneumonia

An intensive care unit-initiated protocol implementing “best practices” significantly reduces ventilator-associated pneumonia, research shows.

8 Oct 2012

HPV status predicts oropharyngeal cancer irradiation response

Human papillomavirus-positive head and neck cancer is more sensitive to the initial effects of radiation therapy than HPV-negative head and neck cancer, suggest study findings.

8 Oct 2012

VTE risk highlighted for rheumatoid arthritis patients

Individuals with rheumatoid arthritis are at an increased risk for venous thromboembolism, research confirms.

8 Oct 2012

Fertility treatment may increase MS disease activity

Findings published in Annals of Neurology suggest that assisted reproduction technology treatment increases multiple sclerosis disease activity.

8 Oct 2012

Early blood pressure control reduces future CV events in diabetes

Type 2 diabetes patients who fail to properly control their blood pressure within a year of being diagnosed with hypertension face an elevated risk for future major cardiovascular events for up to 3 years subsequently, study results show.

8 Oct 2012

Myocutaneous flap shows promise in pediatric Achilles tendon repair

A free partial latissimus dorsi myocutaneous flap can be used for the treatment of severe contracture of the Achilles tendon and posterior ankle in children, and achieves satisfactory form and function, the results of a case series indicate.

8 Oct 2012

Wait until infection is confirmed before starting antimicrobials in ICU

Delaying antimicrobial treatment of patients in the surgical intensive care unit who have a suspected hospital-acquired infection does not increase the risk for mortality, and may even be associated with better outcomes than starting antimicrobials before culturing blood, say researchers.

8 Oct 2012

Low-dose aspirin may protect against cognitive decline in elderly women

Elderly women at risk for cardiovascular events who take low-dose acetylsalic acid exhibit less cognitive decline on the Mini Mental State Examination than their peers who do not take the drug, report researchers.

8 Oct 2012

Combined medical–dental visits for infants could reduce Medicaid payouts

An office-based preventive oral health program has resulted in low monthly dental treatment rates for its infant-age Medicaid beneficiary participants, and reduced the likelihood of their hospitalization for dental matters, show US study results.

8 Oct 2012

Many children incorrectly restrained in cars

Car accidents are the main cause of serious injury and death among children in Norway. A new study from the Norwegian Institute of Public Health shows that 37 per cent of all children under 16 years are incorrectly restrained in the car. 23 per cent of children are so poorly restrained that a collision would have very serious consequences. The study results were presented at a seminar on traffic accidents in Oslo on 8th October.

8 Oct 2012

Continuous computerized surveillance has negative effects

To understand the effects of continuous computerized surveillance on individuals, a Finnish research group instrumented ten Finnish households with video cameras, microphones, and logging software for personal computers, wireless networks, smartphones, TVs, and DVDs.

8 Oct 2012

High levels of chronic and acute illnesses in Palestinian refugees

New research draws attention to the continuing and urgent health emergency facing Palestinians living under occupation, especially the health and wellbeing issues surrounding refugees from the occupied Palestinian territories. Abstracts of the research, which were presented at the fourth meeting of The Lancet Palestinian Health Alliance in March 2012, are published online in The Lancet.

8 Oct 2012

New neuroprotective agent for stroke patients potentially found

Scientists have shown that a drug called NA-1 results in fewer brain lesions in patients who have undergone surgery to repair a brain aneurysm, compared to placebo, and appears to be safe to use, according to an Article published Online First in The Lancet Neurology.

8 Oct 2012

Merck receives non-exclusive license to use Delphi StabyExpress technology

Delphi Genetics SA has announced today a broad licensing agreement with a subsidiary of Merck & Co., Inc., known as MSD outside the United States and Canada, for the use of the StabyExpress technology, which allows high yield, cost effective protein expression without the use of antibiotics.

8 Oct 2012

ImaginAb enters into neurodegeneration research collaboration agreement with Lundbeck

ImaginAb, Inc., a clinical-stage company developing in vivo molecular imaging agents based on antibody fragment technology, today announced that it has entered into a collaboration and commercialization agreement with H. Lundbeck A/S.

8 Oct 2012

Trellis, OMT enter collaboration to generate human antibodies

Trellis Bioscience LLC and Open Monoclonal Technology, Inc. today announced a new collaboration where the companies will join forces to generate human antibodies against therapeutic targets identified by Trellis and its partners using OMT's OmniRat platform.

8 Oct 2012

Rainbow, Amarantus report joint venture agreement for NuroPro Parkinson's diagnostic platform

Rainbow Coral Corp. biotech subsidiary Rainbow BioSciences and Amarantus Biosciences have moved into the final stages of the terms for a deal. The pending joint venture agreement will see the two entities working together to move the Amarantus NuroPro Parkinson's diagnostic platform towards commercialization.

8 Oct 2012

Researchers discover new group of nerve cells that regulate processes of learning and memory

Swedish researchers at Uppsala University have, together with Brazilian collaborators, discovered a new group of nerve cells that regulate processes of learning and memory. These cells act as gatekeepers and carry a receptor for nicotine, which can explain our ability to remember and sort information.

8 Oct 2012