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Cellectis, Medicago complete first step in therapeutic protein research collaboration

Medicago Inc., a biopharmaceutical company focused on developing highly effective and competitive vaccines based on proprietary manufacturing technologies and Virus Like Particles, and Cellectis plant sciences, a US-based subsidiary of Cellectis Group, the specialist in genome engineering, today announced the successful completion of the first step in their research collaboration to improve therapeutic proteins produced in tobacco plants.

4 Oct 2012

New mathematical formulas can evaluate kidney function with age

Within the framework of a Berlin cohort study, scientists from Charité - Universitätsmedizin Berlin have succeeded in developing new mathematical formulas that dependently assess kidney function with age.

4 Oct 2012

Prevalence of diabetic complications is race-specific

Diabetes is among the ten leading causes of death in both white and African American patients, but the prevalence of diabetic complications are race-specific, according to a recent study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM).

4 Oct 2012

Tuberous sclerosis complex lesions respond well to everolimus in EXIST

Results from two phase III trials demonstrate significantly better skin lesion reduction with everolimus than placebo in patients with tuberous sclerosis complex.

3 Oct 2012

Beta blockers do not lower cardiac risk in patients with or without CAD

Beta-blocker therapy does not reduce the risk for cardiovascular events in patients with or without coronary artery disease, researchers say.

3 Oct 2012

Rare study highlights anal cancer prognosis risks

The presence of palpable, clinically involved inguinal lymph nodes and male gender are both independent risk factors for poor prognosis in anal cancer, confirm the results of a UK analysis.

3 Oct 2012

Cleaning-product-related asthma concern for hospital workers

Research suggests that exposure to cleaning products, particularly those containing decalcifiers and ammonia, may increase the risk for asthma in female hospital workers.

3 Oct 2012

Structured deliberation improves neonatal decision-making process

The implementation of a structured multiprofessional medical ethical decision-making process could improve decision-making in neonatal intensive care units, show study results from the Netherlands.

3 Oct 2012

Antifungal resistance of Candida genital isolates on the increase

Resistance to antifungal therapy of genital-infection causing Candida species may be an increasing problem, suggests research presented at the European Academy of Dermatology and Venereology annual congress in Prague, Czech Republic.

3 Oct 2012

Early bone graft plus rhinoplasty significantly improves facial esthetics in UCLP

The facial esthetic of children with unilateral cleft lip and palate is significantly improved with early alveolar bone grafting alongside rhinoplasty, versus leaving the procedure until the child is older, study findings show.

3 Oct 2012

Routine screening influences outcomes in prostate cancer after surgery

Men who undergo radical prostatectomy for a tumor that was detected by screening show better long-term outcomes than their peers who undergo the surgery after opportunistic diagnosis, study results show.

3 Oct 2012

Differentiating features of BD, early-onset ADHD identified

Research findings published in the Journal of Abnormal Child Psychology have identified differentiating features between early-onset bipolar disorder and combined attention-deficit/hyperactivity disorder.

3 Oct 2012

Executive attention deficits identified in first-episode schizophrenia

Patients with first-episode schizophrenia have impairments in executive attention but not in alerting or orienting attention, suggest findings published in Bipolar Disorders.

3 Oct 2012

Foreign Accent Syndrome individuals overemphasize given information

Individuals with Foreign Accent Syndrome often place pitch accents on given information, instead of de-accenting such elements, and encounter problems in signaling the status of information, the results of a UK study indicate.

3 Oct 2012

Complement dysregulation underpins pre-eclampsia

Pre-eclampsia is associated with increased classical pathway activation and altered complement regulation, suggest Dutch results indicating that the extent of complement dysregulation may be related to the severity of pre-eclampsia.

3 Oct 2012

BMI concerns raised for childhood stem cell transplantation survivors

Childhood survivors of hematologic malignancies treated with allogeneic hematopoietic stem cell transplantation should undergo long-term monitoring of their body mass index and lean body mass, US researchers recommend.

3 Oct 2012

Alarms could be key to avoiding intraoperative awareness

Bispectral index monitoring is unlikely to be better than monitoring based on anesthetic concentrations for preventing intraoperative awareness, shows a randomized trial.

3 Oct 2012

Extended thrombolysis window has potential pitfall

The benefits gained from extending the window for thrombolysis in patients with stroke could be lost if the more generous deadline causes physicians to relax, a study suggests.

3 Oct 2012

Babies’ facial expressions after jab reveal pain type

Researchers have discerned seven distinct facial expressions in babies immediately after vaccination, which they say could signal different types of pain and aid communication of distress to caregivers.

3 Oct 2012

Haploidentical bone marrow transplants for sickle cell disease: an interview with Dr. Javier Bolaños Meade

Bone marrow transplant (also called stem cell transplant) is a medical intervention that allows a physician to deliver very high doses of chemotherapy (if needed) but more importantly, deliver a new immune system to the patient to fight a disease (such as cancer).

3 Oct 2012