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Alcohol douses the blood pressure benefit of red wine

Alcohol-free red wine Is more effective at lowering blood pressure than traditional red wine or gin, a study shows.

13 Sep 2012

Social cognition reduced in FEP, UHR patients

First-episode psychosis patients show widespread impairments in social cognition, and such impairments are also evident, albeit to a lesser extent, in those at ultra-high risk for psychosis, researchers report.

13 Sep 2012

Kynurenic acid levels reduced in suicide attempters with schizophrenia

Cerebrospinal fluid concentrations of kynurenic acid are significantly lower in schizophrenia-spectrum patients with a history of suicide attempts than in those without, researchers report.

13 Sep 2012

Gefitinib shows promise in Chinese lung cancer patients

Gefitinib improves progression-free survival, overall response, and health-related quality of life over carboplatin/paclitaxel for first-line advanced non-small-cell lung cancer treatment, a study indicates.

13 Sep 2012

Smoking history 'no bar to successful lung donation'

Although lung transplantation from donors with a positive smoking history is associated with worse outcomes than with lungs from non-smoking donors, survival is still better than remaining on the waiting list, say UK researchers.

13 Sep 2012

Disorganized eggs hinder fertility in obese women

Severely obese women are at an increased risk for producing eggs that have multiple spindles and disorganized chromosomes, possibly explaining the reduced fertility in this population, report researchers.

13 Sep 2012

Autologous skin grafts heal chronic foot ulcers

Scientists have successfully treated chronic diabetic foot ulcers using skin grafts grown from individual patient cell samples.

13 Sep 2012

Stigma impacts functioning in bipolar disorder

Higher levels of perceived stigma are associated with poorer functioning in patients with bipolar disorder, research shows.

13 Sep 2012

Platinum tissue concentrations predict NSCLC treatment response

Reduced tissue platinum accumulation might explain why some patients with non-small-cell lung cancer fail to respond to platinum-based chemotherapy, research shows.

13 Sep 2012

Crizotinib may be effective treatment option for NSCLC subtype

Phase I trial results show that the chemotherapy drug crizotinib may be fast-acting and produce long-lasting treatment responses in patients with anaplastic lymphoma receptor tyrosine kinase-positive non-small-cell lung cancer.

13 Sep 2012

SOX2 gene potential therapeutic target for SCLC

Expression of the Sry-related HMG box 2 gene is higher in small-celllung cancer tissue samples than in non-cancerous lung tissue samples, according to findings from a genetic study.

13 Sep 2012

Solubilized curcumin shrinks lung tumors in mice

Belgian researchers report that orally administered curcumin can reduce the size of lung cancer tumors in mice.

13 Sep 2012

Addition of sorafenib to chemotherapy does not prolong survival

The addition of sorafenib to gemcitabine/cisplatin fails to provide any additional benefit in chemotherapy-naïve patients with nonsquamous non-small-cell lung cancer, research shows.

13 Sep 2012

Model predicts lung cancer risk

Researchers have shown that The Liverpool Lung Project Risk Model is effective in identifying those at the highest risk for lung cancer within 5 years, and who are therefore suitable for computed tomography screening.

13 Sep 2012

Dabigatran increasingly being used off-label

Dabigatran has increasingly been used for off-label indications, including venous thromboembolism, in the USA between 2007 and 2011, a study suggests.

13 Sep 2012

Infants’ oral microbiota differs according to feeding method

The oral microbiota of 3-month old infants is distinguishable by whether they are breast- or formula-fed, show study findings.

13 Sep 2012

FDG–PET/CT improves staging and modifies radiotherapy management

The addition of FDG–positron emission tomography/computed tomography revised radiotherapy decision-making and enhanced tumor staging capabilities in patients with non-small-cell lung cancer, research shows.

13 Sep 2012

Think ‘glass half full’ to reduce pain after breast surgery

Women who undergo surgery for breast cancer are less likely to experience postoperative pain if they have an optimistic personality, but are more likely to experience it if they already had preoperative pain, shows an analysis of the Study of Recovery after Breast Surgery.

13 Sep 2012

People with family history of certain diseases often underestimate their risk

People with a family history of certain diseases, including heart disease and diabetes, often underestimate their risk for developing them, even after completing a risk assessment and receiving personalized prevention messages, finds a new study in the American Journal of Preventive Medicine.

13 Sep 2012

Incidence of Acute gastrointestinal illness is likely to rise in coming years

The distribution system piping in U.S. public water systems that rely on non-disinfected well water or "ground water" may be a largely unrecognized cause of up to 1.1 million annual cases of acute gastrointestinal illness (AGI), involving nausea, vomiting and diarrhea, scientists are reporting. Their study in ACS' journal Environmental Science & Technology concludes that such illnesses may become more of a problem as much of the nation's drinking water supply system continues to age and deteriorate.

13 Sep 2012