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Consortium database model compares favorably for RCC prognosis

The International Metastatic Renal-Cell Carcinoma Database has been externally validated and is now ready for application, researchers report.

20 Feb 2013

COX-2 inhibitor extends sunitinib activity in renal cell carcinoma

The effectiveness of sunitinib for the treatment of renal cell carcinoma could be enhanced with the addition of a cyclooxygenase-2 inhibitor, study findings show.

20 Feb 2013

Metastatic tumors best for sunitinib response evaluation in mRCC

When evaluating treatment response in non-nephrectomized patients with metastatic renal cell carcinoma, the primary lesion does not have to be selected as the target lesion, researchers report.

20 Feb 2013

Possible alternative to biopsy discovered for renal cancer diagnosis

Combining positron emission tomography scanning with iodine-124 (124I)–girentuximab may offer an effective noninvasive method of diagnosing clear cell renal cell carcinoma in patients who present with a renal mass, US study results suggest.

20 Feb 2013

Air pollution exposure raises cardiac death rate

Long-term exposure to high levels of particulate matter with a diameter of 2.5 mm or below increases a person’s chance for dying following a heart attack, show results from a large UK study.

20 Feb 2013

Modifiable risk factors found for violence in schizophrenia

Researchers have identified modifiable risk factors for increased violence in people with psychosis that could prove important for risk assessment and management.

20 Feb 2013

Perinatal episodes prevalent in women with mood disorders

Perinatal mood episodes are highly prevalent in women with bipolar disorder and recurrent major depression, UK research shows.

20 Feb 2013

Dog owners concerned about daily living with osteoarthritis

Carprofen for the treatment of dogs with osteoarthiritis significantly improves owner-assessed chronic pain as well as lameness compared with placebo, show US study results.

20 Feb 2013

Growth in opioid use prompts safety concerns

Prescriptions for opioid drugs have increased significantly in Germany over the past decade, a survey of insurance data has found.

20 Feb 2013

AMD risk alleles fail to predict treatment response

The major risk alleles that influence the development of age-related macular degeneration do not predict response to therapy for the condition, a substudy of the CATT trial indicates.

20 Feb 2013

Symptom severity, hospice patient distress not necessarily linked

End-stage heart failure patients being treated in hospices have multiple symptoms with potential to cause distress, indicate US study findings.

20 Feb 2013

Misconduct biased fluid resuscitation studies

There are “serious safety concerns” associated with the use of hydroxyethyl starch for fluid resuscitation in critically ill patients, say the authors of a meta-analysis in JAMA.

20 Feb 2013

Predictive value of prostate cancer gene 3 validated

Researchers have confirmed that the prostate cancer gene 3 is a valid predictor for current cancer and future biopsy outcomes.

20 Feb 2013

‘Liver first’ approach first choice for metastatic rectal cancer

Using the “liver first” approach to treat locally advanced rectal cancer and synchronous liver metastases allows nearly three-quarters of patients to receive optimal neoadjuvant therapy and resection for both their primary tumor and metastases, researchers report.

20 Feb 2013

Air pollution associated with increased deaths after heart attacks

Air pollution contributes to an increased number of deaths among patients who have been admitted to hospital with heart attacks, according to a study published online in the European Heart Journal

20 Feb 2013

Heart OMics in AGEing project receives European Commission grant

The HOMAGE (Heart OMics in AGEing) project, coordinated by the French National Institute of Health and Medical Research (INSERM), has been awarded a grant by the European Commission for a 6 year period.

20 Feb 2013

Study assesses ischaemic and haemorrhagic risk linked with history of stroke or TIA

Heart and cerebro-vascular disorders represent the two leading causes of death throughout the world. They are sometimes combined in a single patient and their combination represents both a considerable risk to the patient and a therapeutic challenge.

20 Feb 2013

Researchers analyze more than 60 brands of cheese available in supermarkets for pollutants

Researchers at the University of Las Palmas de Gran Canaria (Spain) have analysed more than 60 brands of cheese commonly available in supermarkets. The concentration of organochloride contaminants in the majority of the samples was lower than levels set by European legislation, but in a few cases it was higher.

20 Feb 2013

University of Louisville research team explores H1N1 outbreak

Just the mention of H1N1 can conjure up images of long lines of people waiting to be vaccinated, news reports of the severity of the pandemic and the count of the number of people who perished from the 2009-10 outbreak. However, some positives are coming forward.

20 Feb 2013

Medical nutrition therapy can play an important role in acne treatment

A study published in the Journal of the Academy of Nutrition and Dietetics has determined that there is increasing evidence of a connection between diet and acne, particularly from high glycemic load diets and dairy products, and that medical nutrition therapy (MNT) can play an important role in acne treatment.

20 Feb 2013