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Study: Deficiency of protein causes age-related memory loss and Alzheimer's disease

A team of Columbia University Medical Center (CUMC) researchers, led by Nobel laureate Eric R. Kandel, MD, has found that deficiency of a protein called RbAp48 in the hippocampus is a significant contributor to age-related memory loss and that this form of memory loss is reversible.

29 Aug 2013

Study points to potential new therapeutic target for preventing birth defects in women with diabetes

A research team at the University of Maryland School of Medicine has identified a cell signaling pathway which plays a significant role in causing developmental defects of the fetal spinal cord and brain in babies of women with diabetes.

29 Aug 2013

Fewer children in UK diagnosed with ADHD than in USA

New research suggests that children are far less likely to be diagnosed with Attention deficit hyperactivity disorder in the UK than they are in the USA. However, the same study, led by the University of Exeter Medical School, suggests that autism diagnosis is still rising.

29 Aug 2013

Researchers identify possible treatment strategy for ALS and other neurodegenerative disorders

Researchers have tied mutations in a gene that causes amyotrophic lateral sclerosis and other neurodegenerative disorders to the toxic buildup of certain proteins and related molecules in cells, including neurons. The research, published recently in the scientific journal Cell, offers a new approach for developing treatments against these devastating diseases.

29 Aug 2013

Reversing inflammation in fluid near brain's cortex may provide solution to Parkinson's disease

Reversing inflammation in the fluid surrounding the brain's cortex may provide a solution to the complex riddle of Parkinson's, according to researchers who have found a link between pro-inflammatory biomarkers and the severity of symptoms such as fatigue, depression and anxiety in patients with the chronic disease.

29 Aug 2013

Research findings may help scientists develop anthrax treatments for humans

Researchers at the National Institute of Allergy and Infectious Diseases and the National Heart, Lung, and Blood Institute, both part of the National Institutes of Health, have identified the cells in two distinct areas of the body that are simultaneously targeted for damage by anthrax toxins, eventually causing illness and sometimes death. Their findings, which appeared online today in Nature, are based on testing in mice.

29 Aug 2013

WPI researchers receive NIH grant to develop cell therapies for healing cardiac muscle

The National Institutes of Health (NIH) has awarded a five-year, $1.94 million grant to a biomedical research team at Worcester Polytechnic Institute (WPI) working at the forefront of cell therapies for healing cardiac muscle damaged by heart attack or chronic disease.

29 Aug 2013

Research links increased breast cancer risk to more alcohol drinking before motherhood

Here's a sobering fact for millions of young women heading back to school: The more alcohol they drink before motherhood, the greater their risk of future breast cancer.

29 Aug 2013

Tumor vessel density linked to mRCC treatment response

Changes in tumor vessel density correlate with response and resistance to anti-angiogenic therapy in patients with metastatic renal cell carcinoma, study findings suggest.

28 Aug 2013

Muscle density improves mRCC prognosis prediction

Patients with metastatic renal cell carcinoma treated with targeted therapies have a better prognosis if they also have a high quality of muscle, study findings indicate.

28 Aug 2013

Time to RCC recurrence prognostic threshold challenged

A large study confirms the prognostic value of time to recurrence after surgery for renal cell carcinoma, and also suggests the need to reduce the threshold for early recurrence.

28 Aug 2013

Findings support partial nephrectomy for T1b RCC

Partial nephrectomy and radical nephrectomy provide comparable cancer control for T1b renal cell carcinoma, yet use of the less radical approach has remained limited in the USA over recent years, study results show.

28 Aug 2013

Testosterone improves exercise capacity in men with COPD

A systematic review and meta-analysis confirms that testosterone therapy improves exercise capacity in men with chronic obstructive pulmonary disease.

28 Aug 2013

Inflammatory status upregulated in first-episode schizophrenia

Patients with first-episode schizophrenia exhibit upregulation of key proinflammatory molecules, study findings show.

28 Aug 2013

Personality may be key to genetics of bipolar disorder

People with bipolar disorder vary significantly from their unaffected relatives, and from healthy controls, on several measures of personality, a study shows.

28 Aug 2013

Tumor Suppressor May Actually Drive Cancer Development

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28 Aug 2013

New research focuses on perfectionism to improve treatment for adolescent anorexia

Reducing ‘perfectionistic’ thinking as a way to improve treatment for adolescent anorexia, is the focus of new research by Griffith University.

28 Aug 2013

Study paves way for understanding the crucial role of lncRNA in human neurons

Scientists at A*STAR's Genome Institute of Singapore have discovered an unusual gene that controls the generation of neurons. This important finding, which is crucial in understanding serious diseases of the brain such as Alzheimer's disease, was reported in the 8th August 2013 issue of the prestigious scientific journal, Molecular Cell.

28 Aug 2013

Researchers suggest new therapeutic target for brain tumor

Johns Hopkins researchers say they have found a specific protein in nearly 100 percent of high-grade meningiomas — the most common form of brain tumor — suggesting a new target for therapies for a cancer that does not respond to current chemotherapy.

28 Aug 2013

Novel machine learning-based approach used to predict hepatotoxic potential of DNA drug

New classes of therapeutic antisense oligonucleotides can have toxic effects on the liver. A novel machine learning-based approach used to predict the hepatotoxic potential of an antisense drug based on its chemical sequence is presented in Nucleic Acid Therapeutics, a peer-reviewed journal from Mary Ann Liebert, Inc. publishers.

28 Aug 2013

Medical Research News

Study: Deficiency of protein causes age-related memory loss and Alzheimer's disease

Study points to potential new therapeutic target for preventing birth defects in women with diabetes

Fewer children in UK diagnosed with ADHD than in USA

Researchers identify possible treatment strategy for ALS and other neurodegenerative disorders

Reversing inflammation in fluid near brain's cortex may provide solution to Parkinson's disease

Research findings may help scientists develop anthrax treatments for humans

WPI researchers receive NIH grant to develop cell therapies for healing cardiac muscle

Research links increased breast cancer risk to more alcohol drinking before motherhood

Tumor vessel density linked to mRCC treatment response

Muscle density improves mRCC prognosis prediction

Time to RCC recurrence prognostic threshold challenged

Findings support partial nephrectomy for T1b RCC

Testosterone improves exercise capacity in men with COPD

Inflammatory status upregulated in first-episode schizophrenia

Personality may be key to genetics of bipolar disorder

Tumor Suppressor May Actually Drive Cancer Development

New research focuses on perfectionism to improve treatment for adolescent anorexia

Study paves way for understanding the crucial role of lncRNA in human neurons

Researchers suggest new therapeutic target for brain tumor

Novel machine learning-based approach used to predict hepatotoxic potential of DNA drug

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