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Pathologist experience critical for accurate Gleason score

Researchers from Hungary have found that concordance between the preoperative and postoperative staging of prostate cancer in patients undergoing radical prostatectomy increases with pathologist experience.

9 Sep 2013

Neural clue to poor daytime concentration in insomnia

Researchers have found abnormal neural function in patients with primary insomnia, which may help explain why these patients find it hard to concentrate on daytime tasks despite the absence of objectively measured cognitive deficits.

9 Sep 2013

Holes found in primary care insomnia management

Better education and training for management of sleep problems is needed, including a clear primary care pathway to treatment, suggests the experience of patients and clinicians in the UK.

9 Sep 2013

Pemetrexed-erlotinib shows second-line efficacy in advanced NSCLC

Combination therapy with pemetrexed and erlotinib significantly improves progression-free survival as compared with either drug alone in patients with advanced non-squamous non-small-cell lung cancer, a phase II study has found.

9 Sep 2013

Early respiratory infections linked to Type 1 diabetes

Researchers from Germany have found that respiratory infections in early life are linked to islet autoimmunity, implicating them as a potential risk factor in the development of Type 1 diabetes.

9 Sep 2013

Doubt cast on worth of BP load

Blood pressure load may not be a useful clinical measure, say researchers.

9 Sep 2013

Dementia catheterization rate a ‘cause for concern’

Researchers from the UK have found that patients with dementia presenting in primary care with urinary incontinence are significantly more likely to receive pharmacologic treatment or be catheterized than other patients.

9 Sep 2013

Hepatitis C services in the UK: an interview with Louise Campbell, senior liver nurse at Imperial College Healthcare NHS Trust

Within the UK there are several centres whose nurse specialists work to a best practice model, delivering care and achieving outcomes which are extremely high in areas of patient retention, adherence to medication and completion of the treatment regimen. With this they achieve cure rates which are some of the highest in the World.

9 Sep 2013

Sleep-deprived people may buy more high-calorie foods the following day

People who were deprived of one night’s sleep purchased more calories and grams of food in a mock supermarket on the following day in a new study published in the journal Obesity, the official journal of The Obesity Society.

7 Sep 2013

Researchers investigate importance of STAT1 phosphorylation in NK cells

Since its discovery in the early 1990s, the protein STAT1 (Signal Transducer and Activator of Transcription 1) has been found to be central in passing signals across immune cells, ensuring that our bodies react quickly and appropriately to threats from viruses or other pathogens.

7 Sep 2013

Shuyusan-containing serum protects SH-SY5Y cells against corticosterone-induced impairment

Synthetic antidepressants present a narrow spectrum and side effects following long-term application. Recently, medical practitioners have shown interest in the use of Chinese medicines for the treatment of diseases and in the adjustment of the human response to stress.

7 Sep 2013

Penn’s ITMAT symposium addresses topics of direct relevance to translational science

The Institute for Translational Medicine and Therapeutics' 7th Annual International Symposium (ITMAT) symposium, Harnessing the Paradox: Personalization and the Science of Scale, to be held in October 2013, will address topics of direct relevance to translational science.

7 Sep 2013

Study reveals hydrolyzed collagen may be suitable for nerve cell culture media

In the central nervous system, nerve cells adhere to the extracellular matrix. Type I collagen is the major class of insoluble fibrous proteins in the extracellular matrix. A previous study has shown that neural stem and progenitor cells, cultured on collagen matrices, are able to expand actively and generate neurons.

7 Sep 2013

Research team receives nearly $17M to focus on nanopore technology in DNA sequencing

The use of nanopore technology aimed at more accurate and efficient DNA sequencing is the main focus of grants awarded by the National Institutes of Health. The grants - nearly $17 million to eight research teams - are the latest awarded through the National Human Genome Research Institute (NHGRI)'s Advanced DNA Sequencing Technology program, which was launched in 2004. NHGRI is part of NIH.

7 Sep 2013

NIH awards nearly $14M grants to research on how genetic factors influence susceptibility to disease

Five research teams have received new four-year awards to study the genomics of disease susceptibility in ethnically diverse populations. The projects aim to unravel the subtle variations in genetic makeup among groups - including African-Americans, Asian-Americans, Hispanics and more - that may account for differences in risks for conditions such as high blood pressure and high blood lipids, in addition to common diseases such as cancer and heart disease.

7 Sep 2013

BMP linked to increased risk of benign tumors, not cancers

Patients undergoing spinal fusion surgery with bone morphogenetic protein (BMP) appear to be at increased risk of benign tumors—but not cancers, reports a study in the September issue of Neurosurgery, official journal of the Congress of Neurological Surgeons. The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health.

7 Sep 2013

ARRO recognizes 56 educators with 2013 ARRO Educator of the Year Award

The Association for Residents in Radiation Oncology (ARRO) has recognized 56 educators with the 2013 ARRO Educator of the Year Award.

7 Sep 2013

Researchers take detailed images of morphing structure of Parkinson’s protein

Researchers have taken detailed images and measurements of the morphing structure of a brain protein thought to play a role in Parkinson's disease, information that could aid the development of medications to treat the condition.

7 Sep 2013

Researchers find key mechanism behind Alzheimer's disease

Alzheimer's disease affects more than 26 million people worldwide. It is predicted to skyrocket as boomers age-nearly 106 million people are projected to have the disease by 2050.

7 Sep 2013

Basic fibroblast growth factor can protect endplate in motor neurons of injured spinal cord

In current studies, the degeneration and protection measures in the distal end of the injured spinal cord and target organ muscle effector have scarcely been investigated. The distal end of the spinal cord and neuromuscular junction may develop secondary degenera-tion and damage following spinal cord injury because of the loss of neural connections.

7 Sep 2013

Medical Research News

Pathologist experience critical for accurate Gleason score

Neural clue to poor daytime concentration in insomnia

Holes found in primary care insomnia management

Pemetrexed-erlotinib shows second-line efficacy in advanced NSCLC

Early respiratory infections linked to Type 1 diabetes

Doubt cast on worth of BP load

Dementia catheterization rate a ‘cause for concern’

Hepatitis C services in the UK: an interview with Louise Campbell, senior liver nurse at Imperial College Healthcare NHS Trust

Sleep-deprived people may buy more high-calorie foods the following day

Researchers investigate importance of STAT1 phosphorylation in NK cells

Shuyusan-containing serum protects SH-SY5Y cells against corticosterone-induced impairment

Penn’s ITMAT symposium addresses topics of direct relevance to translational science

Study reveals hydrolyzed collagen may be suitable for nerve cell culture media

Research team receives nearly $17M to focus on nanopore technology in DNA sequencing

NIH awards nearly $14M grants to research on how genetic factors influence susceptibility to disease

BMP linked to increased risk of benign tumors, not cancers

ARRO recognizes 56 educators with 2013 ARRO Educator of the Year Award

Researchers take detailed images of morphing structure of Parkinson’s protein

Researchers find key mechanism behind Alzheimer's disease

Basic fibroblast growth factor can protect endplate in motor neurons of injured spinal cord

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

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