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UofL wins NIH grant for cardiac clinical research center

During his 18-year tenure at UofL, Dr. Roberto Bolli has generated more than $100 million in grants for basic research from the NIH. Today, Bolli joined with University of Louisville President James R. Ramsey to announce a new NIH grant he has won for clinical research, a seven-year, $3.4 million grant from the National Heart, Lung and Blood Institute to establish one of seven regional centers across the United States in the Cardiac Cell Therapy Research Network.

10 Apr 2012

Fatty acids fight cancer spread

Tiny agents found in omega-3 could potentially be used to block the path of primary cancer tumors, preventing the advance to secondary stage cancers according to pharmacy researchers at the University of Sydney.

9 Apr 2012

Eggs developed from stem cells could change reproductive technology

Scientists have developed human egg cells that have been grown entirely in the laboratory from stem cells. These could be fertilized later this year in a development that will revolutionize fertility treatment and might even lead to a reversal of the menopause in older women.

9 Apr 2012

Study shows causal effect of obesity on medical care costs

Obesity now accounts for almost 21 percent of U.S. health care costs - more than twice the previous estimates, reports a new Cornell University study.

9 Apr 2012

Nursing research news from Johns Hopkins

Two decades ago, the landmark Cruzan decision catalyzed individual thinking, policy discussions and lawmaking about advance care directives and choices.

7 Apr 2012

Anti-gay bias linked to lack of awareness of one's sexual orientation and authoritarian parenting

Homophobia is more pronounced in individuals with an unacknowledged attraction to the same sex and who grew up with authoritarian parents who forbade such desires, a series of psychology studies demonstrates.

7 Apr 2012

'Benefits and burdens' of participating in clinical research trials

In one of the first studies of its kind, University of Pennsylvania School of Nursing researchers have identified what cancer patients consider the "benefits and burdens" of participating in clinical research trials.

7 Apr 2012

Heart Rhythm Journal manuscript by Dr. Hauser inaccurate and biased, says St. Jude Medical

St. Jude Medical, Inc., a global medical device company, today announced it is seeking a retraction of the manuscript accepted for publication in the Heart Rhythm Journal by Dr. Robert Hauser, et al., titled, "Deaths Caused by the Failure of Riata and Riata ST Implantable Cardioverter-Defibrillator Leads."

7 Apr 2012

Elevated pulse pressure may increase risk of CVD in older adults with AD

Researchers at the University of California, San Diego and Veterans Affairs San Diego Healthcare System have shown that elevated pulse pressure may increase the risk of cerebrovascular disease (CVD) in older adults with Alzheimer's disease.

7 Apr 2012

PloS ONE publishes research on GenVec's new vaccine vectors

GenVec, Inc. announced publication of research on GenVec's new vaccine vectors. These vectors circumvent neutralizing antibodies in order to generate the desired immunologic response.

7 Apr 2012

Presage Biosciences enters cancer research agreement with Millennium

Presage Biosciences, a leader in identifying clinically viable oncology drug combinations, today announced that it has entered into a cancer research agreement with Millennium: The Takeda Oncology Company.

7 Apr 2012

Innate patient factors, overall morbidity affect neurodevelopment in infants with single-ventricle disease

In the largest multicenter clinical trial of children undergoing early-stage surgery for single-ventricle heart defects, differences in intraoperative management did not significantly affect neurodevelopmental outcomes at 14 months of age. Instead, the strongest influences were innate patient characteristics and general medical morbidity during the child's first year of life.

6 Apr 2012

NIH to award $20M over 5 years to support global health training for scientists

"A network of global health research training institutions will increasingly focus on the rising levels of chronic diseases in developing countries, the National Institutes of Health Fogarty International Center announced on Wednesday," CQ HealthBeat reports (Bristol, 4/4).

6 Apr 2012

Measuring executive functions may predict 'game intelligence' in soccer players

Measuring what are known as executive functions, which reflect the cognitive ability to deal with sudden problems, may make it possible to predict how good an elite soccer player will become in the future. This has been shown by a new study from Karolinska Institutet in Sweden. Scientists believe for the first time that they have found the scientific key to what has previously been described as 'game intelligence' in successful soccer players.

6 Apr 2012

Researchers understand TG paradox in people of African descent

In most people, high blood levels of the fat known as triglycerides are an early warning sign of type 2 diabetes and metabolic syndrome, but in people of African descent these dangerous health conditions may go undiagnosed because triglyceride levels are not at the level used to diagnose metabolic syndrome (>150 mg/dL). This is known as the "TG (or lipid) paradox."

6 Apr 2012

Zalicus' cHTS platform identifies synergistic drug combinations for treatment of cancer

Adenosine A2A and beta-2 adrenergic receptor agonists are highly synergistic and selective novel agents that enhance glucocorticoid activity in B-cell malignancies such as multiple myeloma and, importantly, can synergize in combination with current multiple myeloma treatment regimens such as melphalan, lenalidomide, bortezomib and doxorubicin.

6 Apr 2012

Key finding in regulation of intraocular pressure in glaucoma

A six-year collaboration between two faculty members of Bascom Palmer Eye Institute of the University of Miami Miller School of Medicine has yielded new insight regarding the regulation of intraocular pressure (IOP) in glaucoma - an irreversible blinding disease that causes progressive visual impairment due to optic nerve damage and is the leading cause of blindness worldwide.

6 Apr 2012

Cancer diagnosis associated with suicide, cardiovascular death

People who are diagnosed with cancer have a markedly increased risk of suicide and cardiovascular death during the period immediately after being given the diagnosis. This has been shown in a new study from Karolinska Institutet in Sweden, published in the prestigious scientific journal The New England Journal of Medicine.

6 Apr 2012

Advaxis, Karolinska Institutet enter collaboration to develop cat allergy vaccine

Advaxis, Inc.,, a leader in developing the next generation of immunotherapies for cancer and infectious diseases, announced that it has entered into a research collaboration with Professor Marianne van Hage, research group leader and Head of the Clinical Immunology and Allergy Unit and Vice Head of the Department of Medicine at Karolinska Institutet in Stockholm, Sweden.

6 Apr 2012

PTSD could be genetically predicted

PTSD can occur after any kind of experience that causes trauma, whether that be in war, after a natural disaster or because of child abuse or sexual assault. Symptoms can include flashbacks, feeling emotionally numb or hyper-alert to danger, and avoiding situations that act as reminders of the original trauma. It is estimated that up to 3% of the general population is likely to be affected by PTSD at some point.

5 Apr 2012