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MDD with subthreshold hypomania ‘should be merged with bipolar II’

Patients with major depressive disorder plus subthreshold hypomania exhibit significant differences in disease course, symptoms, treatment-seeking rates and other characteristics compared with those with major depression alone, research shows.

10 Oct 2012

Hemophilia bleeding risk ‘low’ for childhood sports

Vigorous physical activity is associated with a moderate but transient bleeding risk for hemophilia, resulting in an overall low risk for bleeds, suggests a study of Australian children.

10 Oct 2012

Bacterial pathogen ‘acutely’ involved in otitis media

Alloiococcus otitidis can be a dominant bacterial pathogen among indigenous Australian children with acute otitis media with perforation, although its main role appears to be that of a secondary pathogen, preliminary study findings suggest.

10 Oct 2012

People with diabetic foot ulcers more likely to die prematurely

People with diabetes who develop foot ulcers are at more risk of dying prematurely than those without the complication, finds a new large-scale study. The researchers say the findings highlight the potential need for improved detection and management of those with diabetes and foot ulcers.

10 Oct 2012

Obesity rate high among children admitted to hospital

A study by researchers at the Graduate Entry Medical School, University of Limerick and Dalhousie University in Canada has found 34% of children between 6-12 years old admitted to hospital are overweight or obese.

10 Oct 2012

Endocannabinoid system most vulnerable to cannabis during adolescence

The system of the brain responsible for mediating the effects of cannabis, the endocannabinoid system, is most vulnerable to the drug during adolescence, according to new research.

10 Oct 2012

Neuroprotectant success in aneurysm coiling

Treatment with the novel neuroprotective agent NA-1 reduces the number of ischemic infarcts sustained by patients undergoing coiling of cerebral aneurysms, show the ENACT results.

9 Oct 2012

CT technique could improve COPD classification

The parametric response map technique can be used in chronic obstructive pulmonary disease to distinguish between disease subtypes, say US researchers.

9 Oct 2012

HVLA manipulation comes out top for low-back pain

Spinal high-velocity-low-amplitude manipulation for the treatment of nonspecific low-back pain has shown to be superior to a nonsteroidal anti-inflammatory drug, researchers report.

9 Oct 2012

Transfused blood age does not impact outcomes in premature babies

Using fresh red blood cells for premature babies who need blood transfusions does not improve outcomes over use of standard blood bank donations, show study findings published in JAMA.

9 Oct 2012

High personality disorder comorbidity rates identified in anxiety

A meta-analysis covering 30 years of research has identified high rates of comorbid personality disorders across a number of anxiety disorder subtypes.

9 Oct 2012

PUFA levels reduced in schizophrenia patients

Results from a systematic review and meta-analysis show that erythrocyte membrane concentrations of certain polyunsaturated fatty acids are reduced in the brains of people with schizophrenia.

9 Oct 2012

Kynurenic acid levels increased in bipolar patients with psychotic features

Bipolar disorder patients with a history of psychotic features have higher cerebrospinal fluid concentrations of kynurenic acid (KYNA) than those without such features, research shows.

9 Oct 2012

Physical activity fights cognitive dysfunction after stroke

A program of aerobic and resistance training helps patients overcome cognitive deficits occurring as a result of stroke, shows research presented at the 3rd Canadian Stroke Congress in Calgary, Alberta.

9 Oct 2012

Reconditioning advised in orthostatic intolerance

Deconditioning is present in almost all patients with orthostatic intolerance, report US researchers.

9 Oct 2012

Point-of-care testing speeds patients through ED

Using point-of-care testing, instead of sending samples to a central laboratory, reduces the length of time that patients stay in the emergency department, shows a randomized trial.

9 Oct 2012

Two novel GFR equations predict kidney function in elderly

Researchers report that two “new” equations may accurately measure kidney function in elderly individuals with nonsevere kidney disease.

9 Oct 2012

Early communication strategies improve end of liver transplant patients’ lives

A multidisciplinary communication intervention involving physicians and family members of liver transplant patients treated in surgical intensive care units can improve end-of-life care, show study results.

9 Oct 2012

Isolated fetal echogenic bowel ‘may be benign’

Results of a Dutch study show that the majority of fetuses with fetal echogenic bowel carry a good prognosis.

9 Oct 2012

MRI method ‘cuts breast cancer false‑positives’

Assessing apparent diffusion coefficients during dynamic contrast-enhanced magnetic resonance imaging may reduce the number of avoidable false‑positive breast cancer results and unnecessary biopsies, show findings published in Radiology.

9 Oct 2012