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Multiple Epo doses with hypothermia offers neonate neuroprotection

Multiple doses of erythropoietin in combination with hypothermia could be neuroprotective in neonates with hypoxic‑ischemic encephalopathy, say researchers.

1 Oct 2012

New treatment target brings hope for scleroderma patients

Research presented at the European Academy of Dermatology and Venereology in Prague, Czech Republic, suggests that inhibition of the SMAD protein may be a viable therapeutic target in scleroderma patients.

1 Oct 2012

Oil blend plus antihypertensive lowers blood pressure, cholesterol level

A blend of sesame and rice bran oil could reduce blood pressure by almost as much as an antihypertensive medication, say researchers.

1 Oct 2012

Genetic profile predicts postradiation erectile dysfunction

Scientists have identified a group of genetic markers that can predict the risk for erectile dysfunction after radiotherapy for prostate cancer.

1 Oct 2012

Multicomponent strategies needed to prevent in-hospital delirium

Delirium in hospitalized adult patients indicates poor long-term outcomes and should be identified promptly and dealt with using evidence-based multicomponent strategies, suggest the authors of a systematic review.

1 Oct 2012

ED discharge satisfaction related to symptom understanding, duration

While the majority of older patients treated and released from emergency departments understand their discharge information, half do not understand how long their condition could last, and a third do not understand medication warnings, show study results.

1 Oct 2012

Pediatric lower respiratory illness continues after hospital discharge

One-third of children hospitalized with severe lower respiratory illness have chronic moist cough a year after discharge, research shows.

1 Oct 2012

CBT ‘has no impact’ on juvenile fibromyalgia physical activity

Cognitive behavior therapy is not associated with increased physical activity levels in adolescents with juvenile fibromyalgia, research shows.

1 Oct 2012

Autoimmune disease myasthenia gravis halted in mice

Working with mice, Johns Hopkins researchers say they have developed a gene-based therapy to stop the rodent equivalent of the autoimmune disease myasthenia gravis by specifically targeting the destructive immune response the disorder triggers in the body.

1 Oct 2012

PLATO: Causes of lower mortality with ticagrelor identified

The mortality reduction with ticagrelor versus clopidogrel is due to fewer deaths from cardiovascular, bleeding, and infection complications, say researchers.

1 Oct 2012

WBC counts in diabetes risk prediction

An elevated white blood cell count in young men is an independent predictor for the development of diabetes in later life, suggest study findings.

1 Oct 2012

Shin splints most common musculoskeletal injury in runners

The common form of musculoskeletal injury in runners is medial tibia stress syndrome, commonly known as shin splints, followed by achilles tendinopathy and plantar fasciitis, show the results of a systematic review.

1 Oct 2012

Artificially sweet success at curbing childhood weight gain

Substituting sugar-sweetened drinks with artificially sweetened alternatives could help reduce weight gain in schoolchildren, research suggests.

1 Oct 2012

Participatory pay-for-performance improves primary care

Both quality of care measures and patient experience may be achieved through the introduction of a participatory pay-for-performance program, study findings indicate.

1 Oct 2012

Dramatic rise in total knee arthroplasty, associated infection rates over past 20 years

Study findings document a steep rise in total knee arthroplasty procedures over the past 20 years, being driven by both an increase in the number of patients enrolled in Medicare and greater per capita utilization.

1 Oct 2012

Level of vision, not gain in letters seen, marks success of AMD treatment

The number of patients with a particular level of vision may be a better mark of the success of treatment for neovascular age-related macular degeneration than the gain or loss of letters able to be seen in logMAR chart testing, suggest researchers.

1 Oct 2012

Clinical need, effectiveness, fairness should drive drugs allocation

A policy that is transparent, fair to patients and healthcare providers, and is based on clinical need is an ethically justifiable approach to rationing drugs that are in critically short supply, report researchers.

1 Oct 2012

Novel target identified for fragile X-linked autism

Researchers have elucidated a novel mechanism through which fragile X syndrome may contribute to behavioural symptoms of autism and identified a potential therapeutic target.

1 Oct 2012

Cannabis abuse in FEP patients predicts poor symptom control

Patients with first-episode psychosis and comorbid cannabis abuse are at high risk for poor symptom control even when on medication, suggest findings published in Schizophrenia Research.

1 Oct 2012