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Study reveals expansion of NK cells after acute infection

The natural killer cells of our immune defense are activated for an extended period after the acute infection, which challenges the prevailing view that the elevation and activation of cells quickly pass.

3 Mar 2011

New research: Weight discrimination may impact physical health

The discrimination that obese people feel, whether it is poor service at a restaurant or being treated differently in the workplace, may have a direct impact on their physical health, according to new research from Purdue University.

3 Mar 2011

Scientists find reprogramming-associated mutations in hiPSCs

Ordinary human cells reprogrammed as induced pluripotent stem cells may ultimately revolutionize personalized medicine by creating new and diverse therapies unique to individual patients.

3 Mar 2011

Groundbreaking discovery in lymphoma research

BC Cancer Agency scientists have discovered that a single gene, CIITA, is implicated in almost 40 per cent of primary mediastinal B-cell lymphomas and 15 per cent of all Hodgkin lymphoma cases.

3 Mar 2011

New study examines boxing injuries among children and adolescents from 1990 to 2008

The risk and nature of injury in the sport of boxing has generated a great deal of controversy in the medical community, especially in relation to youth boxing. A new study, conducted by researchers in the Center for Injury Research and Policy of The Research Institute at Nationwide Children's Hospital, examined boxing injuries among participants 6 years of age and older from 1990 to 2008.

3 Mar 2011

Early diagnosis of juvenile idiopathic arthritis critical to avoid disability, deformity

While lab tests and imaging can sometimes help diagnose juvenile idiopathic arthritis (JIA), a physical examination and thorough patient history are the most valuable tools in identifying this disease. According to a new literature review from the Journal of the American Academy of Orthopaedic Surgeons (JAAOS), the rate of false positives in laboratory evaluations and imaging studies meant to screen for juvenile arthritis makes their value limited.

3 Mar 2011

Birth of healthy child does not resolve depression and anxiety in women who miscarry

The depression and anxiety experienced by many women after a miscarriage can continue for years, even after the birth of a healthy child, according to a study led by University of Rochester Medical Center researchers and published online today by the British Journal of Psychiatry.

3 Mar 2011

New study: Significant deterioration in semen quality during last 10 years in Finland

A new study published in the International Journal of Andrology reveals that semen quality has significantly deteriorated during the last ten years in Finland, a country that previously was a region with high sperm counts.

3 Mar 2011

U-M scientists identify potential target to treat aggressive prostate cancer

Researchers at the University of Michigan Comprehensive Cancer Center have identified a potential target to treat an aggressive type of prostate cancer. The target, a gene called SPINK1, could be to prostate cancer what HER2 has become for breast cancer.

3 Mar 2011

ITI, Takeda collaborate to develop and commercialize PDE1 inhibitors for schizophrenia

Intra-Cellular Therapies, Inc. ("ITI") and Takeda Pharmaceutical Company Limited, today announced that they have entered into an exclusive collaboration to develop and commercialize selective phosphodiesterase type 1 (PDE1) inhibitors, discovered by ITI, for the treatment of cognitive impairment associated with schizophrenia. This agreement is targeted worldwide, but ITI has retained the option to co-promote with Takeda in the United States.

3 Mar 2011

Scientists provide new insight into mechanisms controlling programmed cell death pathways

Work led by St. Jude Children's Research Hospital investigators provides fresh insight into mechanisms controlling programmed cell death pathways and offers new targets in the fight against cancer and virus-infected cells

3 Mar 2011

Women smokers over 50 at increased risk of breast cancer

Compared to women who had never smoked, breast cancer risk increased by nine percent among former smokers and by 16 percent among current smokers according to research by Karen Margolis, MD, a senior clinical investigator with the HealthPartners Research Foundation and her collaborators in a study that was published today in the British Medical Journal.

3 Mar 2011

New study: Lower potassium levels may help explain racial disparity in type 2 diabetes

Lower potassium levels in the blood may help explain why African-Americans are twice as likely to be diagnosed with type 2 diabetes as whites, according to a new study by Johns Hopkins researchers.

3 Mar 2011

Night shift work may reduce risk of skin cancer in women

Melatonin is known to have cancer-protective properties, and shift work can induce desynchrony of the circadian system, reducing melatonin production. Shift work has been thought to have important health impacts, with evidence linking shift work to an increased risk of several cancers including breast, endometrial, prostate, and colorectal, and non-Hodgkin lymphoma.

2 Mar 2011

Ibuprofen may protect against development of Parkinson's disease

New research suggests that ibuprofen may offer protection against developing Parkinson's disease, according to one of the largest studies to date investigating the possible benefits of the over-the-counter drug on the disease. The study is published in the March 2, 2011, online issue of Neurology®, the medical journal of the American Academy of Neurology.

2 Mar 2011

Study: Fluoride forms on teeth is up to 100 times thinner than previously believed

In a study that the authors describe as lending credence to the idiom, "by the skin of your teeth," scientists are reporting that the protective shield fluoride forms on teeth is up to 100 times thinner than previously believed.

2 Mar 2011

Study identifies key gene mutation responsible for type 2 diabetes in nearly 10% of patients

A multinational study has identified a key gene mutation responsible for type 2 diabetes in nearly 10 percent of patients of white European ancestry.

2 Mar 2011

BigThink.com launches breakthroughs: Discussion highlighting cutting-edge cancer research

Everyone knows someone that has been touched by cancer. Over one and a half million Americans will be diagnosed with some form of cancer in 2011, and more than 560,000 will die from the disease, accounting for 1 out of every 5 deaths.

2 Mar 2011

Researchers find mineral deficiency increases type 2 diabetes risk in African-Americans

Lower potassium levels in the blood may help explain why African-Americans are twice as likely to be diagnosed with type 2 diabetes as whites, according to a new study by Johns Hopkins researchers.

2 Mar 2011

Genetic variants determine severity of HCV-related graft disease and antiviral treatment response

German researchers have found a significant association of IL28B genotypes to interferon-based antiviral treatment outcome, and to graft inflammation caused by hepatitis C virus (HCV). The study determined that the presence of G-allele serves as a marker for severe HCV-induced graft inflammation, as well as a predictor for unsuccessful treatment. Study findings—the largest to report on the role IL28B variants in a transplant cohort with recurrent HCV—are published in the March issue of Liver Transplantation, a journal of the American Association for the Study of Liver Diseases.

2 Mar 2011

Medical Research News

Study reveals expansion of NK cells after acute infection

New research: Weight discrimination may impact physical health

Scientists find reprogramming-associated mutations in hiPSCs

Groundbreaking discovery in lymphoma research

New study examines boxing injuries among children and adolescents from 1990 to 2008

Early diagnosis of juvenile idiopathic arthritis critical to avoid disability, deformity

Birth of healthy child does not resolve depression and anxiety in women who miscarry

New study: Significant deterioration in semen quality during last 10 years in Finland

U-M scientists identify potential target to treat aggressive prostate cancer

ITI, Takeda collaborate to develop and commercialize PDE1 inhibitors for schizophrenia

Scientists provide new insight into mechanisms controlling programmed cell death pathways

Women smokers over 50 at increased risk of breast cancer

New study: Lower potassium levels may help explain racial disparity in type 2 diabetes

Night shift work may reduce risk of skin cancer in women

Ibuprofen may protect against development of Parkinson's disease

Study: Fluoride forms on teeth is up to 100 times thinner than previously believed

Study identifies key gene mutation responsible for type 2 diabetes in nearly 10% of patients

BigThink.com launches breakthroughs: Discussion highlighting cutting-edge cancer research

Researchers find mineral deficiency increases type 2 diabetes risk in African-Americans

Genetic variants determine severity of HCV-related graft disease and antiviral treatment response

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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