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PGDx to identify novel kinase targets in collaboration with Blueprint Medicines

Personal Genome Diagnostics Inc., today announced that it will use its proprietary methodologies and expertise in genomic analysis of defined cancer subtypes to identify novel kinase targets in collaboration with Blueprint Medicines.

21 May 2013

Difficult-to-interpret patterns important for complex brain functions

Many brain researchers cannot see the forest for the trees. When they use electrodes to record the activity patterns of individual neurons, the patterns often appear chaotic and difficult to interpret. "But when you zoom out from looking at individual cells, and observe a large number of neurons instead, their global activity is very informative," says Mattia Rigotti, a scientist at Columbia University and New York University who is supported by the SNSF and the Janggen-Pöhn-Stiftung.

21 May 2013

U-M-led researchers examine factors that contribute to resurgence of pertussis

Whooping cough has exploded in the United States and some other developed countries in recent decades, and many experts suspect ineffective childhood vaccines for the alarming resurgence.

21 May 2013

New research suggests that listening to music lowers anxiety, sedation in ventilated patients

New research suggests that for some hospitalized ICU patients on mechanical ventilators, using headphones to listen to their favorite types of music could lower anxiety and reduce their need for sedative medications.

21 May 2013

Kidneys discarded for transplant can be used for manufacturing replacement organs, say researchers

Nearly 20 percent of kidneys that are recovered from deceased donors in the U.S. are refused for transplant due to factors ranging from scarring in small blood vessels of the kidney's filtering units to the organ going too long without blood or oxygen. But, what if instead of being discarded, these organs could be "recycled" to help solve the critical shortage of donor organs?

21 May 2013

Multiple studies examine ideal biomarkers for Huntington's disease

While Huntington's disease (HD) is currently incurable, the HD research community anticipates that new disease-modifying therapies in development may slow or minimize disease progression. The success of HD research depends upon the identification of reliable and sensitive biomarkers to track disease and evaluate therapies, and these biomarkers may eventually be used as outcome measures in clinical trials. Biomarkers could be especially helpful to monitor changes during the time prior to diagnosis and appearance of overt symptomatology.

21 May 2013

Diachisis can occur during subacute phase of ischemic stroke, find USF researchers

While the effects of acute stroke have been widely studied, brain damage during the subacute phase of stroke has been a neglected area of research. Now, a new study by the University of South Florida reports that within a week of a stroke caused by a blood clot in one side of the brain, the opposite side of the brain shows signs of microvascular injury.

21 May 2013

Nighttime intensivists have no effect on ICU length of stay, find researchers

With little evidence to guide them, many hospital intensive care units have been employing critical care physicians at night with the notion it would improve patients' outcomes. However, new results from a one-year randomized trial from researchers at Penn Medicine involving nearly 1,600 patients admitted to the Hospital of the University Pennsylvania Medical ICU suggest otherwise: Having a nighttime intensivist had no clear benefit on length of stay or mortality for these patients, not even patients admitted at night or those with the most critical illnesses at the time of admission.

21 May 2013

Childhood maltreatment linked to increased risk of obesity in adult life

Children who have suffered maltreatment are 36% more likely to be obese in adulthood compared to non-maltreated children, according to a new study by King's College London. The authors estimate that the prevention or effective treatment of 7 cases of child maltreatment could avoid 1 case of adult obesity.

21 May 2013

Blind people have potential to use echolocation to locate objects, new research shows

New research from the University of Southampton has shown that blind and visually impaired people have the potential to use echolocation, similar to that used by bats and dolphins, to determine the location of an object.

21 May 2013

UIC researchers to study gender differences in how the heart uses and stores fat

Researchers at the University of Illinois at Chicago College of Medicine will study gender differences in how the heart uses and stores fat -- its main energy source -- and how changes in fat metabolism play a role in heart disease, under a new $2 million, 4-year grant from the National Heart, Lung and Blood Institute.

21 May 2013

Researchers develop new mouse model to discover gene pathways that drive MPNST

University of Minnesota Medical School researchers from the Masonic Cancer Center, University of Minnesota, in partnership with the University's Brain Tumor Program, have developed a new mouse model of malignant peripheral nerve sheath tumors that allow them to discover new genes and gene pathways driving this type of cancer.

21 May 2013

Disruption of brain developmental processes caused by premature birth can affect cognitive function

Researchers from King's College London have for the first time used a novel form of MRI to identify crucial developmental processes in the brain that are vulnerable to the effects of premature birth.

21 May 2013

Groundbreaking germ-fighting vaccine research to be presented at National Biotechnology Conference

A novel vaccine study from South Dakota State University will headline the groundbreaking research that will be unveiled at the American Association of Pharmaceutical Scientists' National Biotechnology Conference.

21 May 2013

Research explores pharmaceutical advances for IBS, hepatitis C

Research presented at Digestive Disease Week explores pharmaceutical advances for treating irritable bowel syndrome with diarrhea and hepatitis C.

21 May 2013

Researchers identify novel biomarkers for predicting mortality in ICU patients

A metabolic profile of intensive care unit patients based on biomarkers of four metabolites can be used to accurately predict mortality, according to a new study.

21 May 2013

Men diagnosed with ADHD in childhood are at higher risk to suffer from obesity as adults: Study

A new study conducted by researchers at the Child Study Center at NYU Langone Medical Center found men diagnosed as children with attention-deficit/hyperactivity disorder were twice as likely to be obese in a 33-year follow-up study compared to men who were not diagnosed with the condition.

21 May 2013

UCLA study: Older men with multiple underlying health problems should avoid prostate cancer treatment

Older prostate cancer patients with other underlying health conditions should think twice before committing to surgery or radiation therapy for their cancer, according to a multicenter study led by researchers in the UCLA Department of Urology.

21 May 2013

Lung Volume Reduction Coil may play key role in treatment of emphysema, study finds

A small, easily implantable device called the Lung Volume Reduction Coil may play a key role in the treatment of two types of emphysema, according to a study conducted in Europe. Results of the study indicate the beneficial effects of the device persist more than a year after initial treatment.

21 May 2013

New computer model predicts when avian influenza strain becomes infectious

A new computer model could help scientists predict when a particular strain of avian influenza might become infectious from bird to human, according to a report to be published in the International Journal Data Mining and Bioinformatics.

21 May 2013

Medical Research News

PGDx to identify novel kinase targets in collaboration with Blueprint Medicines

Difficult-to-interpret patterns important for complex brain functions

U-M-led researchers examine factors that contribute to resurgence of pertussis

New research suggests that listening to music lowers anxiety, sedation in ventilated patients

Kidneys discarded for transplant can be used for manufacturing replacement organs, say researchers

Multiple studies examine ideal biomarkers for Huntington's disease

Diachisis can occur during subacute phase of ischemic stroke, find USF researchers

Nighttime intensivists have no effect on ICU length of stay, find researchers

Childhood maltreatment linked to increased risk of obesity in adult life

Blind people have potential to use echolocation to locate objects, new research shows

UIC researchers to study gender differences in how the heart uses and stores fat

Researchers develop new mouse model to discover gene pathways that drive MPNST

Disruption of brain developmental processes caused by premature birth can affect cognitive function

Groundbreaking germ-fighting vaccine research to be presented at National Biotechnology Conference

Research explores pharmaceutical advances for IBS, hepatitis C

Researchers identify novel biomarkers for predicting mortality in ICU patients

Men diagnosed with ADHD in childhood are at higher risk to suffer from obesity as adults: Study

UCLA study: Older men with multiple underlying health problems should avoid prostate cancer treatment

Lung Volume Reduction Coil may play key role in treatment of emphysema, study finds

New computer model predicts when avian influenza strain becomes infectious

Extending the reach of Amperia™

Modular cleanrooms: Enhancing flexibility and compliance

Redefining control and consistency in anaerobic microbiome workflows

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